Vaccines Work! Scientific Evidence that Vaccines Reduce SARS-CoV-2 Transmission and Save Lives

Vaccines work. They are safe. Everything else is a lie. A supporter of vaccinations holds up a sign while watching a public hearing on vaccine exemption legislation on closed-circuit television, in an overflow room at the Connecticut Legislative Office Building in Hartford, Feb. 19, 2020. This painting shows a cross section through a small respiratory droplet, like the ones that are thought to transmit SARS-CoV-2. The virus is shown in magenta, and the droplet is also filled with molecules that are present in the respiratory tract, including mucins (green), pulmonary surfactant proteins and lipids (blue), and antibodies (tan).

Science News article

THE ORIGINAL FDA REPORTS:
There were about 30,000 people in EACH trial! They were the guinea pigs, you are not!

Below are graphs of data reported to the FDA for the COVID-19 vaccines. About 15,000 people got the vaccine and about 15,000 people got saline (salt water). Neither the person giving or getting the shot knew which was which until after all the data was collected. This is called a "double blind" trial. It means that people's expectations don't affect the results.

The curves are number of COVID-19 cases (vertical) versus time (horizontal). The upper curve is the number of cases for the control unvaccinated people who got saline. Over time this climbs quite regularly. The lower curve is the number of cases for the vaccinated people. Interestingly it goes up until about 11 days and then goes almost flat. The delay is how long the person's body takes to figure out and make antibodies against SARS-CoV-2.

These data clearly show that the vaccines work to prevent COVID-19.

  1. FDA document for Pfizer, PDF link
    Look at Figure 2 on page 30
    FDA report https://www.fda.gov/media/144245/download page 30 showing effectiveness of vaccine
  2. FDA document for Moderna, PDF link
    Look at Figure 2 on page 28
    FDA report https://www.fda.gov/media/144434/download page 28 showing effectiveness of vaccine
  3. FDA document for Janssen
    The relevant PDF is FDA Decision Memorandum February 27, 2021 Look at Figure 1 on page 31
    FDA report page 28 showing effectiveness of vaccine

PAPERS PUBLISHED IN THE SCIENTIFIC LITERATURE :

  1. Efficacy and Safety of the mRNA-1273 SARS-CoV-2 Vaccine
    New England Journal of Medicine 2021 Feb 4;384(5):403-416. 2020 Dec 30.
    Look at Figure 3
  2. Safety and efficacy of the BNT162b2 mRNA COVID-19 Vaccine
    New England Journal of Medicine 2020 Dec 31;383(27):2603-2615.
    Look at Figure 3
  3. Safety and Efficacy of Single-Dose Ad26.COV2.S Vaccine against Covid-19
    New England Journal of Medicine 2021 Jun 10;384(23):2187-2201.
    Look at Figure 2
  4. Effectiveness of BNT162b2 Vaccine against Critical Covid-19 in Adolescents
    New England Journal of Medicine 2021 Jan 12
    "Conclusions
    Among hospitalized adolescent patients, two doses of the BNT162b2 vaccine were highly effective against Covid-19-related hospitalization and ICU admission or the receipt of life support."
  5. Real-world effectiveness of COVID-19 vaccines: a literature review and meta-analysis
    International Journal of Infectious Diseases. 2021 Nov 16
    "Conclusions
    The COVID-19 vaccines are highly protective against SARS-CoV-2-related diseases in real-world settings."
  6. Effectiveness of a second BNT162b2 booster vaccine against hospitalization and death from COVID-19 in adults aged over 60 years
    Nature Medicine. Published: 25 April 2022
    "This study demonstrates a substantial reduction in hospitalizations and deaths due to Covid-19 conferred by a second-booster in Israeli adults aged 60 years and over."
  7. COVID-19-Associated Hospitalizations Among Vaccinated and Unvaccinated Adults 18 Years or Older in 13 US States, January 2021 to April 2022
    JAMA Intern Med. Published: September 8, 2022
  8. Vaccines reduce the risk of long COVID in children
    Nature. Published: 20 December 2023
    "A study shows that US children who received mRNA COVID-19 vaccines have some protection against developing long-lasting symptoms of the coronavirus SARS-CoV-2."
  9. Effect of COVID-19 Vaccines on Reducing the Risk of Long COVID in the Real World: A Systematic Review and Meta-Analysis
    International Journal of Environmental Research and Public Health Published: 29 September 2022
    "Our study shows that COVID-19 vaccines had an effect on reducing the risk of long COVID in patients vaccinated before or after SARS-CoV-2 infection/COVID-19."
  10. The effectiveness of COVID-19 vaccines to prevent long COVID symptoms: staggered cohort study of data from the UK, Spain, and Estonia The Lancet Respiratory Medicine. Published:January 11, 2024
  11. Undervaccination and severe COVID-19 outcomes: meta-analysis of national cohort studies in England, Northern Ireland, Scotland, and Wales The Lancet. Published:January 15, 2024
  12. Estimated number of lives directly saved by COVID-19 vaccination programs in the WHO European Region, December 2020 to March 2023 medRxiv. '~1.4 million lives saved' by vaccination!
  13. Lives saved by COVID-19 vaccines Journal of Paediatrics & Child Health. First published: 20 September 2022. 'vaccinations prevented an estimated 14.4 million deaths'!
  14. Vaccine Effectiveness Against Long COVID in Children Pediatrics. January 16 2024
  15. The role of COVID-19 vaccines in preventing post-COVID-19 thromboembolic and cardiovascular complications Heart.
    Conclusions COVID-19 vaccination reduced the risk of post-COVID-19 cardiac and thromboembolic outcomes. These effects were more pronounced for acute COVID-19 outcomes, consistent with known reductions in disease severity following breakthrough versus unvaccinated SARS-CoV-2 infection.
  16. Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine New England Journal of Medicine. December 10, 2020
  17. Effectiveness of COVID-19 vaccines to prevent long COVID: data from Norway The Lancet Respiratory Medicine. Available online 10 April 2024

QUOTES AND LINKS

  1. "The Earth is round, gasoline is flammable, and vaccines are safe and effective, All the rest are dangerous lies."
    -- Roberto Burioni
  2. Why don't you have a round scar?
  3. Here's what happens if you don't get vaccinated
  4. Baltimore Sun report: Breakthrough cases: get vaccinated, but keep wearing your mask, avoid parties, distance, probably wash too.
  5. Atlantic story: Your Vaccinated Immune System Is Ready for Breakthroughs
  6. 2021 Aug 12 update J. Stacey Klutts, from 2021 August 6. Chief Pathologist at Veterans Affairs Medical Center, Associate professor at University of Iowa Carver College of Medicine
  7. What do all these stories of vaccine denial deaths do to our sense of empathy? By Maura Judkis October 7, 2021 at 6:00 a.m. EDT, Washington Post.
  8. SORRYANTIVAXXER.COM "The purpose of this site is educational, except for a few exceptions, everyone listed on this site was/is an anti-vaxxer activist who helped spread COVID-19 misinformation on social media. Share to stop others from making the same mistake. GET VACCINATED!"
  9. Pandemic Preparedness and Response: Lessons from COVID summary of the current situation as of 2022 Sep 15 by Dr. Fauci.
  10. Dr. Anthony Fauci discusses this winter's outlook for COVID summary of the current situation as of 2022 Sep 20 by Dr. Fauci.
  11. Dr Susan Oliver @DrSusanOliver1 2 new studies provide more evidence that ANTIVAXXER claims that vaccines are causing excess deaths are wrong. Will they continue to ignore the evidence? (no prizes for guessing right) youtube video
  12. Are intelligent people more likely to get vaccinated? The association between COVID-19 vaccine adherence and cognitive profiles. Vaccine. Volume 41, Issue 40, 15 September 2023, Pages 5848-5853 http://dx.doi.org/10.1016/j.vaccine.2023.08.019
    What do you think they found?
  13. Digital measurement of SARS-CoV-2 transmission risk from 7 million contacts
    Nature. Published: 20 December 2023
    "A study shows that US children who received mRNA COVID-19 vaccines have some protection against developing long-lasting symptoms of the coronavirus SARS-CoV-2."
  14. Hydroxychloroquine killed nearly 17 thousand stupid people!!! Deaths induced by compassionate use of hydroxychloroquine during the first COVID-19 wave: an estimate
    Biomedicine & Pharmacotherapy. Published: Volume 171, February 2024
    "Highlights
    • Hydroxychloroquine was prescribed in hospitalised patients with Covid-19 despite of the low-level evidence.
    • Subsequently, HCQ use was associated with an 11% increase in the mortality rate in a meta-analysis of randomized trials.
    • The number of hydroxychloroquine related deaths in hospitalised patients is estimated at 16,990 in six countries.
    • These findings illustrate the hazard of drug repurposing with low-level evidence for the management of future pandemics."
    Discussion on Facebook
  15. Global age-sex-specific mortality, life expectancy, and population estimates in 204 countries and territories and 811 subnational locations, 1950-2021, and the impact of the COVID-19 pandemic: a comprehensive demographic analysis for the Global Burden of Disease Study 2021 The Lancet.

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origin: 2021 Jul 08
updated: 2024 Apr 12