The Left Handed DNA
Hall of Fame


- Tom Schneider
The Left handed DNA Hall of Fame has moved.
Please note the NEW LOCATION:
http://www.fred.net/tds/leftdna/

http://www.fred.net/tds/LeftHanded.DNA.html
    1964

    version = 2.01 of leftyear1989.txt 2009 Sep 29

  1. The earliest Left handed DNA that we are aware of is an Israeli stamp from 1964. The image was sent to me by Irwin Tessman (Department of Biological Sciences Purdue University West Lafayette IN 47907-1392). The stamp is in "Chemistry on stamps (chemophilately)". Rappoport, Z. Acc. Chem. Res., 25(1), 24- 31, 1992. It is in the lower right corner of Figure 2, and is described on page 30 as having 'the "abnormal" helicity of DNA'. Click to see the complete beautiful stamp.
    as of 1998 Nov 23
    1978
  2. The now out of print book, Molecular Biology of the Gene by James D. Watson (W. A. Benjamin, Inc, Menlo Park, California, third Edition, ISBN 0-8053-9609-8) has a series of left handed DNA pictures on pages 228 (fig 9-18), 263 (fig 10-10 and 10-11), 268 (fig 10-16), 290 (fig 11-8), 292 (fig 11-9), and 419 (fig 15-9). (Thanks to Richard Wolf (wolf@umbc.edu) for pointing this one out!) as of 1999 April 23. "There is at least one additional drawing of left-handed DNA on p. 216 (fig 9-9). Also, the Fig. 11-8 on p. 290 is particularly cute in presenting a right-handed structure amidst two left-handed flanks in the same drawing (the central portion showing a hybrid duplex of RNA/DNA, though)." (Thanks to Richard Egel, richard.egel@molbio.ku.dk for pointing this one out!) as of 2000 August 18.
    around 1980
  3. Until Dr. Tessman informed me otherwise in November 1998, the earliest example I was aware of is a beautiful drawing of a circular plasmid by the Beckman Company published around 1980. "Our experience covers over 40 years of innovation and unmatched quality".
  4. On the cover of Nature Volume 284 Number 5757, 17 April 1980 is on left handed "Selfish DNA" (a series of left-handed twisting snakes eating each other in a circle). The person who found it writes:

    Hi there! Yes, I am a Newsweek reader. I am also an artist responsible for perhaps one of the first left-handed boo-boos.

    My husband and his old advisor (Doolittle and Sapienza) wrote a piece on "Selfish DNA" that was accepted by Nature. Their paper and another by Crick and Orgel became the magazine's cover topic. Lucky me! I got to draw for Nature!

    No one noticed that my design was left-handed until the journal was in press. I will admit that the scientists thought it was pretty funny (well, what could they do at that point?).

    In the US the background color was an ugly light orange, but the British version was a vivid red.

    I'm starting to feel like a real part of history here...uh, infamous too.

    ...

    Thanks for a great site!

    (Thanks to Linda Angeloff Sapienza, LASplumas@aol.com, for pointing this one out!)
    as of 2000 May 30
    1982
  5. Principles of Biochemistry by Albert L. Lehninger, Worth Publishers, Inc., New York. ISBN 0-87901-136-X. (added 1998 April 8) Page 850 shows a relaxed left handed DNA circle which when acted on by DNA gyrase with the hydrolysis of ATP to ADP + Pi becomes a supertwisted right-handed DNA.
    1983
  6. The Cartoon Guide To Genetics by Larry Gonick and Mark Wheelis (Barnes & Noble, NY, 1983), is a wonderful and funny introduction but unfortunately the cute RNA polymerase on the cover is chewing away at a left handed DNA. The cover of the updated edition has the even odder DNA that is changing twist as the RNA polymerase moves by. (It's a great book anyway!!)
  7. In a letter Nature 305:176 (1983) John H. Wilson and Peter B. Berget point out that in the advertisement for the Symposium: Molecular Biology Now & Tomorrow was a DNA that was simultaneously left and right handed! (Thanks to John Wilson for pointing this one out.)
    1989
  8. Arthur Kornberg, discoverer of DNA polymerase, wrote a book:
    For the love of enzymes: the odyssey of a biochemist Cambridge, Mass., Harvard University Press, 1989.
    In the section on "Astonishing Machines of Replication" on page 227, figure 7-14 there is a figleaf covering the point of DNA replication, all of the strands coming out of it are left handed.
  9. An Amgen advertisement in Nature 340, 17 August 1989, shows a replicating left-handed DNA in space over the North American continent, with the words "Amgen Biologicals: bringing world class products to the forefront of biomedical research". Space invaders?
  10. The Trends in Biotechnology cover January 1989, Volume 7 No.1 shows both left and right-hand forms coming from a single plant.
    1995

    version = 2.01 of leftyear1995.txt 2009 Sep 29

    1990
  11. The Trends in Biotechnology cover June 1990, Volume 8 No.6 shows an SEM image of a left-handed DNA with the words "Scanning Tunnelling Microscopy of Biomolecules". In the article itself ("Scanning tunnelling Microscopy in Biotechnology", P. G. Arscott and V. A. Bloomfield, page 153), fig 2 shows a left-handed DNA with a figure legend stating that it is "in the left-handed Z form". Yet on page iii is "Front Cover ... A single molecule of B-form DNA ..."
  12. The IBI 1990 Catalog cover two kinds of model, both left handed.
  13. Perkin Elmer Spring 1990 Biotechnology Catalog cover
  14. Bio-Rad Bio-Radiations No. 76, 1990, page 4, "DNA Preparation for Forensic Analysis" with a left-handed helix. To track the space invaders? "Image: Nelson L. Max".
  15. A Genosys advertisement in Trends in Biochemical Research 15(4) April 1990. "Some good things you have to wait for." (under a picture of wine and glasses) "Others you don't." (under a picture of left-handed DNA).
  16. "Logic of the Escherichia coli cell cycle", Richard D'Ari and Philippe Bouloc, cartoon in TIBS May 1990 15(5) 191-194.
  17. Clontech advertisement in Nucleic Acids Research 18(4) July 25, 1990. "we can offer you guaranteed quality and excellent service."
  18. Applied Biosystems meeting "Automating Molecular Biology: Tools and Techniques for the 90's", September 12, 1990, National Institutes of Health, Lipsett Amphitheatre, Bethesda, MD. This company makes the most popular DNA sequencing machine.
  19. Science 1990 Nov 9 issue had business reply cards to join membership in the American Association for the Advancement of Science. The card has the words: ' "I have to read SCIENCE every week" James D. Watson Nobel Laureate' above a left-handed DNA. This appeared in Science in two other formats, one on 1991 Aug 19. The original paper on the structure of DNA is: 
    @article{WatsonCrick1953,
author = "J. D. Watson
 and F. H. C. Crick",
title = "Molecular Structure of Nucleic Acids:
A Structure for Deoxyribose Nucleic Acid",
journal = "Nature",
volume = "171",
pages = "737-738",
year = "1953"}
  20. Biochemistry book by C. K. Mathews and K. E. van Holde, The Benjamin / Cummings Publishing Company, Inc. Redwood City, California, ISBN 0-8053-5015-2, 1990. Page 923 shows RNA polymerases working on left handed DNA that somehow manages to switch over to right handed DNA elsewhere on a circular plasmid. This is a pretty clear example of an artist flipping a drawing over. This textbook drawing was meant to show how transcription can cause supercoiling. It shows two polymerases transcribing towards each other, but with opposite DNA twists. A student could become rather confused: the DNA as drawn would not become supercoiled by the transcription!
  21. Tessman Letter: Genosys Nature 14 June 1990, page xiii
  22. Tessman Letter: ZymoGenetics Science 15 June 1990, in the back
  23. Collaborative Research Science 15 June 1990, in the back
  24. Tessman Letter: Applied Biosystems Science 10 August 1990, p. 610
  25. Tessman Letter: Oncor Science 28 September 1990, p. 1475
  26. Tessman Letter: Clontech Nature 4 October 1990, p. xii
    1991
  27. Tessman Letter: Eppendorf Science 25 January 1991 (I have not confirmed this one.)
  28. In a Letter to Nature volume 350, 21 March 1991, page 184, Irwin Tessman (Department of Biological Sciences Purdue University West Lafayette IN 47907-1392) wrote about the ``Sinister change'' that had already by that time come about. He listed 6 advertisements in Nature 1 5 and Science, 2 3 4 6 a book and a Biotechnology center. Dr. Tessman is the earliest identified DNA Leftologist (people like myself who are puzzled and worried by this growing effect).
    as of 1998 Nov 19
  29. The MIT Technology Review "The Dark Side of the Genome" by Robert A. Weinberg, April 1991. On page 47 is a left-handed helix with with non-inverted letters on the bases next to a right-hand helix coming out of a bacterium. "Illustrations: James Yang", "Diagram: Bohdan D. Osyczka."
  30. The Washington Post cover of section on High Tech Careers, Monday, May 5, 1991.
  31. The Washington Post section on Science/Public Health, page A3, Monday, May 11, 1992. The figure shows left-handed smallpox DNA four times.
  32. Schleicher & Schuell flyer 1991 July 30. "Only One Purification Kit Can Do All This." There are innumerable left-hand DNAs shown.
    1992
  33. Promega advertisement in Biotechniques 12(2), February 1992. "We make the grade like no one else. HeLaScribe (TM) Nuclear Extract - in vitro Transcription Grade"
  34. EG&G Berthold advertisement in Biotechniques 12(2), February 1992. "Now, A Better Way to Measure Gene Expression..." This one is signed: "(c) Schilling '91" running along the left-hand helix, so the inversion could not have happened at the last minute.
  35. Oncogene Science, advertisement in Science 258, 13 November 1992.
  36. USB United States Biochemical, flyer for "Images Non-Isotropic Kits for Detection of Nucleci Acids and Proteins" 1992 December.
  37. Digene Diagnostics. Inc., 1992-1993 Catalog cover has 2 right handed and 2 left handed DNAs.
    as of 1999 Jan 15
    1993
  38. Ambion advertisement showing a machine transcribing left-handed DNA [1993 March].
  39. QIAGEN advertisement for a "Back to Basics" T-shirt [1993 Nov 3]
  40. Nature genetics conference: Human Genetics: Mapping the Future. 1st International Conference, April 1 & 2, 1993, Washington, DC. The symbol g twists to become a left-handed helix. (advertisement in Nature, 28 Jan 1993) Perhaps the date of the meeting explains it?
  41. Amersham Life Science, advertisement in Nature, 28 Jan 1993. Many little DNA drawings, some are left handed.
  42. USB United States Biochemical, advertisement in Nature, 28 Jan 1993.
  43. Promega catalog cover of 1993/94. On the cover is written: "Revolutions in Science" and shows a picture of a left handed DNA strand with a photo of Oswald Avery in the background. What a revolution in science!! I wonder what they are hinting at? Anyway, to top this, the start of chapter four also shows another picture of left handed DNA. (Thanks to: Nico Gey van Pittius, Department of Medical Biochemistry and Physiology, Faculty of Medicine, Tygerberg, 7505, South Africa, Tel : +27-21-938 9402/7, +27-82-896 8949, Fax : +27-21-938 9476, E-mail: ngvp@gerga.sun.ac.za for finding and scanning the image, and for some of the description.) (Click on this cropped image for the complete cover. A closeup of this pretty figure is also available). as of 1999 March 4
    1994
  44. Time January 17, 1994. "Genetics: The future is now". The cover shows a picture of a spread out person with a huge left handed DNA embedded in his chest and abdomen. They refused to allow the cover to be put on this web site! (Thanks to Irwin Tessman, Department of Biological Sciences Purdue University West Lafayette IN 47907-1392. for scanning and sending the jpeg to me.)
    as of 1998 Nov 24
  45. R&D Magazine, April 1994. "ECL Detection Method Speeds Human Genome Mapping Project" pages 32-33 by Howard Goldner. "For more information: Shaf Yousaf, Amersham Life Science".
    I sent email to the editor, Robert Cassidy and he acknowledged the error.
  46. Nature Volume 372 No 6501 3 November 1994. The cover shows Darwin knitting a DNA strand. The end of the strand is right handed, but it switches to left handed further up. The cover was prepared in celebration of 125 years of Nature. The lead article is entitled "Frontiers of Ignorance".
  47. A book by Julie Chen on DNA teaches artists how to do it backwards: Double Helix: An Essential Component of All Living Matter, Berkeley, California, 1994
    as of 1998 Nov 19. 2002 Mar 6:
    1995
  48. "Make your own DNA", Thoki Yen shows how to make a lovely (left handed) DNA model by origami. TIBS February 1995 20(2) page 94.
    This was pointed out by Sean Eddy on a bionet news group. (Thanks to Alex Bateman MRC Laboratory of Molecular Biology, agb@mrc-lmb.cam.ac.uk, Phone: (01223) 402479, http://www.mrc-cpe.cam.ac.uk/jong/agb/origami.html for alerting me. Search for "DNA" on his site for an entire discussion.) 2002 March 6: Unfortunately the original link is broken.
  49. Science volume 269, 28 July 1995, page 468. According to the figure on this page, a new strain of the bacterium Haemophilus influenzae, known to cause ear infections and meningitis, has been found that has left handed DNA. How it is capable of infecting people with right handed DNA is not understood.
  50. Pharmacia Biotech advertisement in BioDirect August 1995 issue 5 volume 1 page 11 shows the cover of "Products for the Purification of [Lefthanded?] Nucleic Acids".
  51. Science volume 270, 13 October 1995, page 252. The article has a figure showing "The yeast a1/alpha2 repressor bound to [left-handed] DNA."
  52. Epicentre Technologies, advertisement in Science volume 270, 24 November 1995. "Now there's a better choice for transgenic DNA packaging. MutaPlax (TM) Transgenic DNA Packaging System ... only from Epicentre."
    To their credit, they acknowledged the error by email.
  53. 1995 NIH RESEARCH FESTIVAL Symposia, workshops and posters, September 18-22. "Cover Design: Artist's rendition of the DNA molecule, courtesy of the National Institute of Aging." WWW link (no image).
  54. H. A. Lim and C. R. Cantor book: 
    Bioinformatics & Genome Research:
Proceedings of the Third International
Florida State Conference Center,
Tallahassee, Florida,
1-4 June 1994.
World Scientific, Singapore.
981-02-2401-X
publication date: Sept 1995
    On the cover there is a computer chip with both left and right handed DNA emerging from it.
  55. R&D Magazine, November 1995 cover.
    To their credit, they acknowledged the error in the January 1996 issue (page 11).
  56. The cover of the 1995 Lab Manual Source Book from Cold Spring Harbor Laboratory Press (now the The BioSupplyNet Source Book) shows a lovely yellow left handed DNA.
    as of 1999 January 28
    1996

    version = 2.00 of leftyear1996.txt 2009 Sep 29

  57. Poster for the meeting: International Symposium on Molecular Virology, Advances in Molecular Basis of Viral Pathogenesi [sic]. Date: Oct 6-10, 1996. Place: Xi'an, China. Host: Chinese Society of Medical Virology. Sponsor: Chinese Medical Association. Supported by: Bristol-Myers Squibb, Glaxo China, Ltd, National Vaccine & Serum Institute of China.
  58. TaKaRa Shuzo Co. LTD. advertisement in The Journal of NIH Research March Volume 8, p. 12, 1996.
  59. Elsevier Science advertisement in Cell March 8, Volume 84, Number 5 1996 for Gene-Combis. (It's nice that they show a sequence logo though! :-)
  60. Taconic advertisement in Science 19 January 1996, Vol 271:278, for Transgenic mouse models.
  61. Schleicher & Schuell advertisement in BioTechniques volume 20, number 4, April 1996, page 645. "PCR-Quality [left handed?] DNA from Whole Blood" ... "a revolutionary new device" ...
  62. Bio-Synthesis Inc. advertisement in American Biotechnology Laboratory April 1996, page 79. Catalog of [left handed DNA?] products.
  63. Rice Biotechnology Quarterly volume 26, April 1996. The cover shows left handed DNA recombining. Are the space invaders evolving now?
  64. Knight-Ridder Information, Inc. advertisement in R&D Magazine April 1996 page 2 shows a rather lovely graphic with both a right hand and part of a left handed DNA.
  65. Millennium Pharmaceuticals, Inc. advertisement in Nature Vol 381 23 May 1996 between pages 346 and 347. A single DNA molecule switches from left- to right- handed. Where the right hand DNA is inspected under a magnifying glass, it becomes left handed. Something is strange about those optics!
  66. Retrogen advertisement in BioTechniques volume 20, number 6, June 1996, page 955. Apparently they synthesize left handed DNA.
  67. Enzo Diagnostics advertisement in Nature Vol 381 13 June 1996 page ii. A single DNA molecule is left-handed and switches to a right hand twist. Why is this mistake gaining popularity?
  68. Wyeth-Ayerst advertisement in Science Vol 272 21 June 1996 page 1826. A single DNA molecule is left-handed and switches to a right hand twist as one goes up the page. This mistake is gaining in popularity!
  69. Technology Review August/September 1996 cover by Marc Burckhardt shows a lovely left-handed DNA twisting around a tree. The cover is about "Misusing Genetics".
  70. Schleicher & Schuell a huge poster received on 1996 July 23 shows one of the "biggest" (77 cm x 39 cm) mistakes so far: a psoralen attacking a left-hand DNA. "Choose the Psoralen Advantage" ... to make your DNA reverse handedness?
  71. Pierce advertisement in Nature Vol 382 25 July 1996 just after page 294. The DNA on the card insert has left hand twist.
  72. Clontech 96/97 catalog. The cover shows a series of left handed DNAs coming out of a machine; the DNAs are stamped "innovation". How are they going to use this innovative product? In the Chapters on PCR-Based Analysis, they show another picture where a left handed DNA is replicated into both left and right handed DNA! Does this mean that they have invented a left handed enzyme? For the section on Libraries, they show a box from which a right then left twist DNA appears from a box.
  73. Perkin-Elmer advertisement flyer. Apparently they have a way to amplify left handed DNA!
  74. Clontech advertisement in Science Vol 273, 2 August 1996, page 552.
  75. As of 1996 Aug 16 a left handed DNA is on the cover of the journal Gene!
    By Spring of 1997, they had corrected the error.
  76. Scientific American, September 1996:
    pages 56-57: people against a background of left handed DNA.
    page 61: left handed DNA for a section titled "Fundamental Understandings" ...
    page 64: both left and right handed DNA in a normal cell
    page 109: DNA hybridizing to "normal" DNA from Hubert Humphrey has a left handed twist. What was he ...?
    The editors responded: "Thanks for pointing out our error in the September issue regarding the handedness of DNA. We have alerted the artists and editors involved. We appreciate your interest in SCIENTIFIC AMERICAN. Sincerely, THE EDITORS"
  77. The cover of the book Independent Birth of Organisms by Periannan Senapathy Shows that frogs came from right handed DNA but that crabs came from left handed DNA. No wonder he claims "that evolutionary theories are fundamentally incorrect".
  78. Bio-Synthesis advertisement in Science Vol 273, 23 August 1996, page 1138. and at their web site. Do they synthesize left handed DNA?
  79. Science volume 273, 30 August 1996, page 1249. An advertising supplement showing a graduating student's left handed DNA tassle.
  80. Nature Volume 383, No 6596, 12 September 1996, page 119. The article "Activation without a vital ingredient" by David M. Chao and Richard A. Young is about how TAFs are not apparently needed for transcriptional activation. The diagram shows transcription from left handed DNA.
  81. 5 Prime -> 3 Prime, Inc mail flyer. received on 1996 September 23 with "products for cloning and molecular biology" shows left handed DNA.
  82. TIBS September 1996 249(21) page 336. Artwork by Bo Segerman showing an entire eukaryotic transcription complex binding left handed DNA.
  83. The Economist's cover of September 14th-20th, 1996 shows a man (or is "nam" a more appropriate name?) walking along as a puppet with left handed DNA attached to the feet, hands and head, and labled "The genetic illusion". Hmm.
  84. NEN Life Science Products Catalog received on 1996 October 24. The cover shows left handed DNA.
  85. PharMingen International advertisement in Nature Vol 384 5 December 1996, 3rd page after page ix. The DNA about to be eaten by a little pacman has left hand twist. (Also in Science Vol 275, 14 Feb 1997, page 894. Also in an advertising poster 1997 Oct 15)
  86. Newsweek's cover December 23, 1996 shows a left handed DNA wrapped around an ... alien from outer space?
  87. GIBCO BRL PCR Products catalogue from Life Technologies, Inc shows the successful PCR replication of left handed DNA. (Thanks to Denise Rubens, rubens@ncifcrf.gov, for pointing this one out!) as of 1999 June 10
    1997

    version = 2.00 of leftyear1997.txt 2009 Sep 29

  88. Oncogene Research Products 1997 cellular research products catalog. A left handed DNA emerges from a eukaryotic cell. (See figure to the right.)
  89. American Scientist, 1997 March-April: page 105: Darwin puzzles over a quiz while a left handed DNA grows out of a pot on the shelf behind him.
  90. CellGenix advertisement in Nature Vol 385, 13 February 1997, back pages. A left hand twist DNA is shown.
  91. MWG-Biotech GmbH advertisement in Nature Vol 386, 6 March 1997, between pages 28 and 29 has left hand twist DNA, labeled "Magic DNA-Sequencing". They have learned how to sequence this kind of DNA! Their web site is somewhat disappointing because it only shows normal right handed DNA :-(
  92. Cambridge Isotope Laboratories, Inc. advertisement in The Journal of NIH Research volume 9, April 1997, page 61. has two left hand twist DNAs.
  93. R&D Systems Europe Ltd. advertisement in The Journal of NIH Research volume 9, April 1997, page 60. has left hand twist DNAs, an artist "ingenius"ly switched the orientation of their very pretty drawing (illustrated to the right). Their cool Molecular Biology Machine has it the other way though.
  94. A lot of beautiful left handed DNA art (Until they reverse the gif's that is :-).
  95. UNC Biology Department Faculty List. The lovely light colored background image is left handed. (Until they reverse the image that is :-). (Thanks to Juan Pablo Martinez-Soriano, Ph.D. Lab. Patologia Molecular Apdo. postal 629 Irapuato, Gto MEXICO http://www.suva.cinvestav.mx/ irapuato /jpms.html CINVESTAV Unidad Irapuato E-mail: jpms@irapuato.ira.cinvestav.mx Phone (524) 624-4500 Fax (524) 624-5996 for pointing this one out!)
    Gif reproduced with permission.
  96. Amersham Life Sciences advertisement in Nature Vol 386, 10 April 1997, page vi. Their new Thermo Sequenase seems to work on left handed DNA, as capital S is wrapping left handed. It looks like we can now sequence left handed DNA! This is good news for those of us investigating the biology of the space invaders. Gif reproduced with permission. © Amersham International plc 1997 - All rights reserved. Amersham International plc, Amersham Place, Little Chalfont, Buckinghamshire, England, HP7 9NA.
  97. Taconic advertisement in Nature Vol 386, 10 April 1997, page 556. Taconic has created a mouse with Left Handed DNA. Or is it a replacement for earth style mice?
  98. James S. McDonnel Centennial Fellowships advertisement in Nature Vol 386, 10 April 1997, page 556. Research on left handed human genetics will now be funded with these fellowships. Progress should be rapid from this point onwards. (See figure.)
  99. PharMingen International advertisement in Science Vol 276, 11 April 1997, page 207. Organisms with left handed DNA also undergo apoptosis. (See figure to the right, reproduced with permission.)
  100. LI-COR advertisement in Science Vol 276, 11 April 1997, page 281. This company supplies machines that sequence left handed DNA.
  101. The Double Helix by James D. Watson (Weidenfeld & Nicolson, London, 1997 reprint. First published in Great Britain in 1968 by Weidenfeld & Nicolson). This is the account of the original discovery of the structure of DNA by Watson and Crick. The front and back cover of the book show left handed DNA. Good grief!
  102. QIAGEN advertisement in Science Vol 276, 25 April 1997, page 504. Cycle PCR with left handed DNA.
  103. QIAGEN advertisement in Science Vol 276, 16 May 1997, page 1018. The advertisement claims that it is now easy to extract left handed DNA from a variety of plants that look much like Earth plants. Beware! Because of their reversed biochemistry, they are probably poisonous to eat.
  104. Shering-Plough advertisement in Science Vol 276, 16 May 1997, page 1143. Left handed DNA is next to outlines of beings similar to humans.
  105. The journal Human Mutation has a web page that appears to be reporting on newly discovered mutations in CT (contra-terran, ie anti-matter and therefore reversed handed) humans. (It has recently been shown that not only are there biochemically reversed left handed animals, whose biochemistry is reversed, but also there are those that are reversed because they are made of antimatter. ;-) (Note: The print journal cover is right handed.)
  106. Technology Review July 1997 page 47. A left handed DNA winds around a medical staff.
  107. The Science Class You Wish You Had: Seven Greatest Scientific Discoveries in History and the People Who Made Them, by David Eliot Brody and Arnold R. Brody, Paperback, 400 pages. Published by Berkley Pub Group, ISBN: 0399523138. The cover of the book shows a left handed DNA, so the text may be especially meaningful for CT humans.
  108. Science advertisement in Science Vol 276, 27 June 1997, page 2084. Three flags made from left handed DNA, with a heading that "THE RACE IS ON ..." in the competition between CT and regular humans!
  109. PE Applied Biosystems Customer Support booklet, "Giving you the help you need" for your (left handed?) DNA sequencing machine.
  110. The cover of the book DNA Markers: Protocols, Applications and Overviews edited by Gustavo Caetano-Anolles and Peter M. Gresshoff (John Wiley & Sons, Inc, 1997) shows that this book is only for left handed CT humans.
  111. The cover of the book From GENES to CELLS by Stephen Bolsover (Editor), Jeremy S. Hayms, Steve Jones, Elizabeth A. Shepard, and Hugh A. White (John Wiley & Sons, Inc, 1997) shows that this book is ALSO only for left handed CT humans. ISBN 0-471-59792-9
  112. The advertisement for the two books mentioned above, a flier from John Wiley & Sons, Inc also has a left handed DNA on it. There are two copies of each book cover, for a GRAND TOTAL OF FIVE IN ONE SHOT - a true record!
  113. The New York Times Science Times section, Tuesday, October 21, 1997 page B9 shows two DNA helices, one associated with nucleosome "spools" and the other associated with a baby sucking a pacifier and holding a teddy bear. But is the baby human? (Thanks to William R Mcclure for pointing this one out.)
  114. BioTechnica advertisement in Science Vol 276, 19 September 1997, page 1852-3. "From Science to Buisness". CT technology advances: no longer just science, it is now involved in world business.
  115. A catalogue from BioSupplyNet Inc. has a right handed DNA on the front cover and a left handed one on the back cover.
  116. The Second NIH Symposium On Therapeutic Oligonucleotides: Targeting Transcription Factors and Signaling Pathways (December 5, 1997, NIH, Bethesda, MD) has a beautiful poster full of left handed DNAs. At NIH, we of course must consider therapeutics for both normal and CT humans.
  117. Science Vol 278, 5 December 1997, page 1713. Genomic vaccines are being made with mixtures of regular and CT DNA.
  118. W. Yang and K. Mizuuchi, Site-specific recombination in plane view, Structure, 5: 1401-1406, 1997. Figure 1 on page 1402 shows the strand breakage and reunion in site-specific recombination in the Lambda Int family. At the moment of rejoining the DNA strands all switch from right handed to left handed symmetry. The topological consequences of this switch have not been carefully considered.
  119. R. V. Miller, Bacterial Gene Swapping in Nature, Scientific American 278: 66-71 (January 1998). pages 69 shows transformation of a bacterium by left handed DNA.
  120. Library of Science (A Newbridge Book Club) Advertisement flyer for molecular biology books, 1997 December 31, shows a spectacular right handed DNA switching midstream into a left handed one, and a large left handed one in between the "bible for molecular biologists" and "[almost] an entire library of contemporary molecular biology [squeezed] into one volume".
  121. Elsevier Science web page gif noticed on 1997 December 31 at Gene-Combis
    It's pretty easy to see, but making it bigger makes clear that the left handed twist runs through the entire image:
  122. Elsevier Science web page gif noticed on 1997 December 31 at Gene-Combis Features. You don't believe me? I couldn't believe there was a second one either. Here it is enlarged:
  123. Elsevier Science web page gif noticed on 1997 December 31 at GeneCombis for the journal Gene (They did this on the cover of the journal in 1996, item #41.)
    Again, we need to enlarge the left hand part to see the left handed twist:

  124. Henninghausen et al report in The Journal of Biological Chemistry (272: 7567-7569, page 7568, if you have a subscription, you can look at the pdf) that prolactin signaling by Stat5A and Stat5b requires binding to left handed DNA. new as of 2001 April 18 (Thanks to Andrew Farkas, af@alumni.princeton.edu, for pointing this one out!)

    1998

    version = 2.00 of leftyear1998.txt 2009 Sep 29

    1998

    ALTERNATE_TEXT

  125. AGenDA Inc., Advanced Genetic Diagnostic Associates provides Parentage Testing, Genetic Disease Screening, Diagnostic Testing, and Forensic Testing for CT humans. (Thanks to Juan Pablo Martinez-Soriano, Ph.D. Lab. Patologia Molecular CINVESTAV Unidad Irapuato Apdo. postal 629 Irapuato, Gto MEXICO http://www.suva.cinvestav.mx/ irapuato/jpms.html E-mail: jpms@irapuato.ira.cinvestav.mx Voice (462) 39637 Fax (462) 45996 for pointing this one out!)

  126. QIAGEN advertisement in Structure Vol 5, No 12 15 December 1997. "... it's never been so easy!" to do PCR on CT DNA. ALTERNATE_TEXT
  127. QIAGEN web site icon 1998 January 12. They have some wonderful technical resources which magnify CT DNA.
  128. Biogen advertisement in Science Vol 279, 23 January 1998, page 592. "Biogen offers what few companies in our industry can", but they are quiet about the CT projects they are working on, although this is shown prominantly in the advertisement. ALTERNATE_TEXT
  129. DNA Isolation Lab Kit Introduces students to the molecular biology of Left handed DNA. The kit allows the student to extract DNA, precipitate it, spool and observe a mass of DNA from CT organisms. ALTERNATE_TEXT to Florida Plants online, who sell this kit, for asking "What's wrong with this box cover?" on their web page. THIS KIT IS REQUIRED HOMEWORK FOR ALL CREATIONISTS AND PEOPLE WHO DO NOT "BELIEVE IN DNA"!

    The New Creationism: Biology Under Attack
    By Barbara Ehrenreich and Janet McIntosh
    When social psychologist Phoebe Ellsworth took the podium at a recent interdisciplinary seminar on emotions, she was already feeling rattled. Colleagues who'd presented earlier had warned her that the crowd was tough and had little patience for the reduction of human experience to numbers or bold generalizations about emotions across cultures. Ellsworth had a plan: She would pre-empt criticism by playing the critic, offering a social history of psychological approaches to the topic. But no sooner had the word "experiment" passed her lips than the hands shot up. Audience members pointed out that the experimental method is the brainchild of white Victorian males. Ellsworth agreed that white Victorian males had done their share of damage in the world but noted that, nonetheless, their efforts had led to the discovery of DNA. This short-lived dialogue between paradigms ground to a halt with the retort: "You believe in DNA?" http://www.thenation.com:80/issue/970609/0609ehre.htm
    The Nation Digital Edition http://www.thenation.com Copyright (c) 1997, The Nation Company, L.P. All rights reserved. Electronic redistribution for nonprofit purposes is permitted, provided this notice is attached in its entirety. Unauthorized, for-profit redistribution is prohibited. For further information regarding reprinting and syndication, please call The Nation at (212) 242-8400, ext. 226 or send e-mail to Max Block at mblock@thenation.com.

  130. Rhône-Poulenc Rorer advertisement in Nature Vol 392, 12 March 1998, page 223. They have positions for computer work on left handed DNA. "We need a leader with special qualifications dictated by this new field".
  131. Oxford Molecular advertisement in Science Vol 279, 13 March 1998, page 1744. They offer genetic sequence analysis tools for left handed DNA. This is a new advertising gimmick since the computations would be the same for right handed DNA.
  132. QIAGEN 1998 March 17. Flyer with left handed DNA inside a hour-glass. ALTERNATE_TEXT
  133. As reported on the web 1998 March 26, Aperture Imaging has discovered the original planet that the CT reversed-DNA organisms came from! (Thanks to Jan A. Witkowski, Ph.D. Banbury Center, Cold Spring Harbor Laboratory, PO Box 534, Cold Spring Harbor NY 11724-0534, (516) 549-0507, (516) 549-0672 fax, http://www.cshl.org/banbury for pointing this one out!)

    ALTERNATE_TEXT
  134. U. S. News & World Report (April 20 1998 page 63) report how tamoxifen can be used to prevent new tumors in CT humans. (Credit for illustration: Copyright April 20, 1998, U.S.News & World Report. Illustration by Rob Kemp for U.S.News & World Report.)

    ALTERNATE_TEXT

  135. Glen Research 1998 April 29. The company is now providing left handed reagents for DNA synthesis, according to the menu on their web page. Obviously this will make research into left handed DNA much easier. (Thanks to the person who pointed this case out to me - return email to your address bounced!)

    ALTERNATE_TEXT
  136. The Nation. April 13, 1998. The cover and on page 11 show a left handed DNA. The article by Jeremy Rifkin on "The Biotech Century: Human Life as Intellectual Property" discusses the ethical issues of using left handed DNA from reversed humans.
  137. R&D Systems advertisement in Nature volume 393, 14 May 1998 back cover. A helicase appears to be separating a left handed DNA into two strands that are partially replicated.
    ALTERNATE_TEXT
  138. R&D Systems is also specializing in left handed molecular biology reagents. (Web site 1998 May 14)
  139. DiaSorin advertisement in Science volume 280, 15 May 1998, page 1026. Both left and right handed DNAs floating in the sky.
  140. Genome Mapping, Sequencing & Biology Meeting, 13-17 May 1998 as reported in Science volume 280, 22 May 1998, page 1185. According to the cover of the abstract book for this meeting, a major effort is underway to sequence the left handed version of the human genome. Am I the only right handed person left on the planet?!? 8-}
  141. Science volume 280, 22 May 1998, page 1212. Two figures show regulation of left handed DNA control systems.
  142. Invitrogen advertisement in Nature volume 393, 18 June 1998, page i. A new mammalian expression kit apparently for left handed DNA mammals.
  143. Molecular Microbiology volume 28, Number 2, April 1998, Cover! Genetic control systems in left handed bacteria are being revealed. (It is also figure 1 of R. L. Smith and M. E. Maguire, Mol. Microbiol 1998 April 28(2): 217-226.)
    ALTERNATE_TEXT
    ALTERNATE_TEXT Dr. Maguire, who kindly sent me this image, acknowledged the error: "Clearly I missed the LH DNA, possibly because I was far more worried about the cartoonish outer membrane which is NOT a bilayer." (Figure reproduced with permission from Molecular Microbiology.)
  144. The National Instutute of Justice published a report in June 1998 The Unrealized Potential of Left Handed DNA Testing by Victor Walter Weedn and John W. Hicks. binoculars First reported on 2002 Sep 28, new as of 2002 Sep 28 (Thanks to Paul Hengen, swingdude@hotmail.com for pointing this one out!)

    ALTERNATE_TEXT
  145. Plant & Animal Genome VII Conference January 17 - 21, 1999. San Diego, California. Transgenic left-handed DNA animals and plants are now being discussed in major meetings. (Web site 1998 July 1) (Thanks to Juan Pablo Martinez-Soriano, Ph.D. Lab. Patologia Molecular CINVESTAV Unidad Irapuato Apdo. postal 629 Irapuato, Gto MEXICO http://www.suva.cinvestav.mx/ irapuato/jpms.html E-mail: jpms@irapuato.ira.cinvestav.mx Voice (462) 39637 Fax (462) 45996 for pointing this one out!)
    ALTERNATE_TEXT
  146. Quantum Biotechnologies Inc. specializes in providing left handed DNA molecular biology products ALTERNATE_TEXT
  147. Elsevier Science web page background noticed on 1998 July 2 at GeneCombis (I have modified the gif to be black and white and shrunk it. I didn't flip it over though! ;-) This is the original.
  148. U. S. News & World Report (July 27, 1998 page 43). (Illustration by Jon Macdonald for USN&WR.)
  149. DNASTAR advertisement in Science volume 281, 17 July 1998, page 308. The picture depicts the discovery of left handed DNA life forms in the sea. Some of the life forms are also right handed but the left to right ratio is 5 to 2, so *ulp* it looks like they are taking over!
    ALTERNATE_TEXT
  150. The Genesis Code by John F. Case. The cover of this 1997 book has a left handed DNA, and the San Francisco Examiner determined that this is "A SPELLBINDING BIOMEDICAL THRILLER . . . TERRIFYING." *ULP* I'd better read it to find out more about the situation!

    ALTERNATE_TEXT
  151. Genetic Maps and Human Imaginations: The Limits of Science in Understanding Who We Are by Barbara Katz Rothman. The book apparently deals with the ethical issues of sequencing humans who have left handed DNA.

  152. The Gene Letter As of August 1998, "Its main focus is on the ethical, legal and social issues that arise out of genetic advances" for both right and left handed DNA people. ALTERNATE_TEXT (They refused to allow me to show their masthead because they thought people would confuse this web site with theirs and because they think that their artist would not agree.) 1999 Jan 12: Dr. Dorothy Wertz, the chief editor, acknowledged the error. ALTERNATE_TEXT

    ALTERNATE_TEXT
  153. Newsweek August 24, 1998 (page 17) published a cartoon by Jack Ohman (Oregonian editorial cartoonist) indicating that left handed DNA has infiltrated the cartoon world. It is of some interest that DNA does replicate by the method depicted on the right. The little device at the bottom corresponds to the "helicase" enzymes that use the energy molecule ATP to open the DNA. (Thanks to David G. Rhodes, University of Connecticut for finding and scanning the image!)

    ALTERNATE_TEXT
  154. National Institutes of Health 2nd Gene Therapy Policy Conference Gene therapy policy is now being considered for left handed DNA people. Apparently the poster for the Third conference is on the same topic.

    ALTERNATE_TEXT
  155. International Society for History, Philosophy, and Social Studies of Biology web page banner indicates that they are now concerned with these topics for Left handed DNA people.
  156. U. S. News & World Report (October 26, 1998 page 90). There are now plenty of jobs in left handed DNA research.
    ALTERNATE_TEXT
  157. Science Oct 23 1998, Volume 282, Number 5389 cover. This genome issue shows that many species have now been replaced by left handed DNA species. Are you next? ;-) ALTERNATE_TEXT The Left Handed DNA Hall of Fame was listed in Science 13 November 1998: 282 (5392): 1223, NetWatch Hot Picks (The directlink will only work if you have a subscription.)
  158. QIAGEN advertisement in Science on Friday 13 November 1998: 282 (5392):1224, curiously placed on the back side of the page announcing this web site . Just in case you were not sure which way the DNA turns, they announce a new hot line: "Questions about molecular biology?" Below this they show a red phone with a left handed cord of DNA. As John Ludwig, a Microsoft vice president in charge of Java development wrote in an internal email, ``Subversion has always been our best tactic. Subversion is almost invariably a better tactic than a frontal assault . . . it leaves the competition confused, they don't know what to shoot at anymore.'' The CT people have gotten really subtle. (Thanks to Paul Brown BROWNP@cder.fda.gov for pointing this scary one out!) ALTERNATE_TEXT
  159. U. S. News & World Report (November 23 1998 page 58), "Miracle Vaccines". They report that certain pathogens have been discovered to contain both left and right handed DNA. To fight these, the right handed DNA can be extracted and used in a naked DNA vaccine, as shown in this diagram. People with right handed DNA will then express antigens against the right handed proteins on the surface and therefore will be protected from the disease. This is a very smart use of molecular technology! It is still mysterious how these pathogens live using both kinds of DNA. (Credit for illustration: Copyright November 23, 1998, U.S.News & World Report. Illustration by Rod Little for U.S.News & World Report.)
    ALTERNATE_TEXT
  160. DNA Pioneers and Their Legacy by Ulf Lagerkvist, Yale University Press (1998) ISBN 0-300-07184-1. This book reveals that many of the pioneers of DNA technology have left handed DNA!! (Thanks to Jack Tessman, Emeritus Professor of Physics, Tufts University, Medford MA 02155, jack@silcon.com for pointing this one out! He wanted to be acknowledged because ``That way, for a fleeting moment, there will be a Tessman at each end of the list.'' Irwin is his brother ... ;-)
    new as of 1998 Nov 25
    ALTERNATE_TEXT
  161. PBS reports on the new left handed DNA vaccines. (Thanks to Brenda Clewell (clewell@roo.susqu.edu) of Susquehanna University for pointing this one out!)
    new as of 1998 Nov 29
    1999

    version = 2.00 of leftyear1999.txt 2009 Sep 29

    1999

    Our Story So Far: The story line, if you have not had time to follow the previous 150 or so entries (!) is my slow realization that earth is being invaded by left handed DNA people ...

  162. Invitrogen web page background as of 1999 Jan 9. The company specializes in left handed DNA products.
  163. Altheatech advertisement in BioTechniques Vol. 26, No. 1, January 1999. They have purified left handed DNA from a purple and orange snake. This appears to be a native of the CT planet! Jane Maxwell, Vice President, Sales and Marketing, indicates that they discovered this error after they it had gone to print. This image is posted with permission.

  164. Time January 11, 1999, page 49. Genetic footprinting of left handed DNA was reportedly done by Alec Jeffreys in 1984! (Thanks to Antonio Regalado, regalado@mit.edu, Associate Editor Technology Review Massachusetts Institute of Technology, Bldg. W59-200, 201 Vassar Street, Cambridge, MA 02139 for sending me the image.)

  165. The January 1999 Volume 14 Number 1 cover of the journal Spectroscopy indicates that spectroscopic studies are now being performed on left handed DNA. Other than polarization effects, I would expect this to be the same as right handed DNA, but the article doesn't seem to mention it. (Art direction by Sandy Kupsch, image number 59175 from PhotoDisc, Inc. Use their search engine with the word "DNA" to find their inverted DNA image.) The error was acknowledged by Mike MacRae, the Spectroscopy editor and Jennifer Yerkes of PhotoDisc. (Thanks to David G. Rhodes, University of Connecticut for finding sending me the journal issue!)
  166. TIBS 23 December 1998 page 493 cartoon by Simon '98, shows Sherlock looking at a left handed DNA with a magnification glass. He says "Excellent try, my dear Watson, but ... could you bring me a mirror, old boy?" Are people are beginning to realize that there has been a CT invasion? This image is posted with permission.
    (Click on image for a larger version.) Thanks to Jamie Simon (jamie_simon@qm.salk.edu) for drawing this cartoon and for permission to put it on the web.)
  167. The National Library of Medicine's impressive collection of original significant scientific papers Profiles in Science shows that not only did Avery discover DNA but he also had spectacular insight into the existence of left handed DNA.
    This image is posted with permission.
    as of 1999 January 28. They acknowledged the error and said: "However, as luck would have it, it was replaced yesterday with a different image which does not contain DNA."
  168. The UCSF Digital Library has a banner that may be left handed DNA. (Thanks to Paul Hengen (pnh@sirius.com) for pointing this one out!)
    as of 1999 January 28
  169. Lawrence Livemore National Laboratory's Biology and Biotechnology Research Program also has a banner that is definitely left handed DNA. (Thanks to Andy Hockey (a.hockey@ucl.ac.uk) for pointing this one out!)
    as of 1999 January 28. The web site was revised and the original image is not on the main page, but it still is at http://www-bio.llnl.gov/bbrp/gif/dna48.gif (Thanks to Keith Ball, kdb@maxwell.ucsf.edu, http://rainbow.uchicago.edu/~kdb1 for pointing this out!)
  170. Access Excellence (the excellent educational program of Genentech) has discovered a relationship between left and right handed DNA! Apparently under certain conditions (patent pending?) right handed DNA can replicate to produce both forms. (Thanks to Stan Metzenberg (smetz@gte.net) for pointing this one out!) as of 1999 January 30. (2000 December 31: Notice the mismatch between the newly opened strands; this mysertious replication mechanism has not been determined.)
  171. SIMPOSIUM INTERNACIONAL DE BIOTECNOLOGÍA APLICADA Y BIOÉTICA 24, 25 y 26 de marzo de 1999. This appears to be a symposium on the biotechnology of left handed DNA. as of 1999 February 24
  172. This case was corrected and removed by request.
  173. The cover of Oncogene Research Products' 1999 General Catalog "Tools for Biological Research" shows that left handed DNA is controlled by the signal transduction proteins fos and jun, and that proteases can be synthesized from left handed DNA. As shown in the figure to the right, which was taken from their Methods section, they also provide methods for working with left handed DNA.
    as of 1999 March 3
    This image is posted with permission.
  174. The cover of Bioinformatics has a left handed spiral made out of 1s and 0s. I initially didn't include it in this collection because it has no ladder of bases in the middle so it could be anything, not necessarily DNA. However, the editor Gary Stormo says that it was intended to be "digital DNA" and that they are planning to fix it. (Thanks to Gary Stormo, Stormo@colorado.edu, for pointing this one out!)
    as of 1999 March 16
  175. The home page of the NIH National Institute of Mental Health (NIMH) GENETICS RESEARCH BRANCH has a left handed DNA, reflecting the increasing need to help people with mental problems who have left handed DNA. Why, they are right in my own "back yard" since I'm at NIH! (Thanks to Ron Edgar, ron@imagic.weizmann.ac.il, for pointing this one out!)
    as of 1999 March 22
  176. The home page of the NIH National Human Genome Research Institute has both left and handed DNA, to indicate that the effort to sequence the human genome has been changed to sequence both the left and right handed genomes. This is another NIH site!
    as of 1999 March 22

  177. The NIH National Institute on Aging appears to have a new focus, to study whether people tend to age more rapidly due to left handed DNA. Recent Press Releases are on Mild Cognitive and Memory Impairment (3/15/99) and Delirium (3/3/99). This is the third NIH site in a row! Why am I getting dizzy?
    as of 1999 March 24

  178. Invitrogen has some unwound DNA on its 1999 Product Catalog cover that winds up to left handed DNA. What a mesmerizing pretty cover ...
    as of 1999 March 25
  179. The QIAGEN web site product guide page has at least four separate left handed DNAs!





    Each of these points to a page with a left handed banner such as:
    I'm glad to see a company devoted to supporting the DNA isolation needs of molecular biologists studying Left Handed DNA ... *GAK* what am I saying?? Have the CT people infected my mind? Oh, no!! (Thanks to Nico Gey van Pittius, ngvp@gerga.sun.ac.za, for pointing this one out!)
    as of 1999 March 25
    QIAGEN has acknowledged the error and offered to supply the previous images! Thanks!
  180. Thanks to Ron Edgar, ron@imagic.weizmann.ac.il, for pointing out a web site that refuses to be identified.
    as of 1999 March 25
  181. As shown in Roche Molecular Biochemicals' Apoptitoc Pathway Chart, left handed DNA is also degraded by this process. It has been suggested that this is related to the process by which right handed DNA humans are being converted to left DNA handed humans. However, the stronger hypothesis is that the left handed DNA humans are not from earth, as indicated by a report from 10 years ago (Thanks to Nikolaj Vibede, nikolaj.vibede@farmakol.ku.dk, University of Copenhagen, for pointing this one out!)
    as of 1999 March 26
  182. The home page of the NIH National Institute on Alcohol Abuse and Alcoholism According to the person who found this case, it "is rather poor in resolution but it attempts to show a male and female under heavy abuse of alcohol which causes them to see a left handed DNA." (My anonymous source asks: "Am I becoming sufficiently cynical?" No, but you are getting there!)
    as of 1999 March 27
  183. My underground guerrilla-warfare anonymous source also tells me that "The Kesseli Lab at University of Massachusetts at Boston http://fisher.bio.umb.edu/ has three left DNAs at one page... two are happily rotating to the right (is that the biological function of left D.N.A (aka A.N.D) ?) They also explain how to sequence left handed DNA in the scheme (at the middle right on the page) what are they teaching these kids?" Note how there are three phosphates in a vertical column with no distinction between the major and minor grooves ... is this triplex left handed DNA? If so, it would be the first reported case!
    as of 1999 March 27. 2000 December 31: I was alerted by Jennifer Forman that the left handed DNAs have been removed from the lab pages!
  184. The magazine Portable Design reports on page 12 of their February 1999 issue that "Lab-on-a-chip analyzes DNA", and show a diagram of a Labrador retriever happily sailing on a potato chip, with a left handed DNA leash.
    as of 1999 March 27
  185. A QIAGEN advertisement in Nature (28 January 1999, p. xviii) indicates that left handed DNA has now been isolated from tomato, tobacco, maize, potato, wheat, barley, poplar, petunia, geranium, spinach, arabidopsis, elm, pine, rhododendron and oak plants. Apparently plants are being converted also.
    as of 1999 March 30
  186. A PharMingen International advertisement in BioTechniques (Vol.25, No 2 August 1998) was brought to my attention, but it is essentially the same as the one in 1996. However it led us to their web site where a beautiful left handed DNA being bound by an antibody graces the cover of their new 1999 Research Products Catalogue. Such detection schemes will allow more rapid distinction between left and right DNA people for tax purposes. However this new use of genetic technology has ethical dimensions that are being hotly contested.
    as of 1999 April 1

  187. Clinmark dotcom's link page points to a number of companies that do clinical research on left handed DNA people. Their home page also has a tiny left hand DNA link. (Thanks to Gorilla Guerilla for pointing this one out!)
    as of 1999 April 6

  188. The Northwestern University Center for Biotechnology is trying to bridge the gap between the science of Left handed DNA and its commercialization. (Thanks to Gorilla Guerilla for pointing this one out!)
    as of 1999 April 8

  189. The Agricultural Genome Information System has "an integrated system for agricultural genome analysis" of left handed DNA species. (Thanks to Gorilla Guerilla for pointing this one out!)
    as of 1999 April 8

  190. The George Mason University Institute for Biosciences, Bioinformatics and Biotechnology has a left handed DNA on their home page. (Thanks to Gorilla Guerilla for pointing yet another one out!)
    as of 1999 April 11

  191. The cover of the journal European BioPharmaceutical Review for September 1998 and for 1999 This image is posted with permission. has a pretty left handed DNA running across it to indicate that this industry is now using left handed DNA in new pharmaceuticals. (The original is more clear than this gif.) (Thanks to Nikolaj Vibede, nikolaj.vibede@farmakol.ku.dk, University of Copenhagen, for pointing this one out!)
    as of 1999 April 15. They acknowledged and will probably be correcting the cover
  192. The New York Times Science section page D10, Tuesday April 20, 1999 (National Edition) reports that Snips will be used to identify left handed DNA people. (Thanks to Jack Tessman, Emeritus Professor of Physics, Tufts University, Medford MA 02155, jack@silcon.com for pointing this one out!)
    as of 1999 April 22
  193. Operon Technologies Incorporated advertisement in Science (16 April 1999, no 5413, p. 543) indicates that they will synthesize either left handed or right handed DNA for you.
    as of 1999 April 22
  194. MWGAG BIOTECH sent out a flyer with a left handed DNA (blue and green), and has another on their home page.
    as of 1999 April 26.
    The same images appear in an advertisement in Biotechiques vol 27, No.1 July 1999 pages 44, 45 and 51. (Thanks to Ilya Lyakhov, lyakhovi@ncifcrf.gov, for pointing this one out!)
    as of 1999 July 21
  195. An advertisement by JBL Scientific found at the web magazine HMS Beagle shows the very fast injection of DNA into a cell. If you watch carefully you will see that it is left handed. (This is most easily done by opening just the image and then reloading repeatedly.) JBL was "unable to attain a release from the graphics author" so I can't show you the image.
    as of 1999 May 10

  196. A book "Applied Molecular Genetics" by Roger L. Miesfeld (John Wiley & Sons, 1999), has on its cover the same left handed DNA that appeared on the January 1999 cover of Spectroscopy (Thanks to Denise Rubens rubens@ncifcrf.gov for pointing this one out!)
    as of 1999 May 11

    This image is posted with permission.
  197. An icon by Andrzej Krause found at the web magazine HMS Beagle shows a set of people riding a left handed "DNA train" according to the editor Lois Wingerson (lois@hmsbeagle.com) who says that "I'll have to look up your rogue's gallery to make sure we _always_ get it right from now on. :^)". (It's not on their main page but is still in their image archive. as of 1999 May 22

  198. In Figure 1 of an article in Science (Science 284: 757 30 April 1999) we learn that reverse endrocrinology is now being done on Left handed DNA containing people. The so-called "orphan nuclear receptors" are genes that look like the receptor for a hormone, but no hormone has been identified yet. Perhaps the problem is that the hormones are enantiomers (reverse handed)? (Thanks to Jack Tessman, Emeritus Professor of Physics, Tufts University, Medford MA 02155, jack@silcon.com for pointing this one out!) as of 1999 May 23

    Congratulations to everybody who helped find the 37 left handed DNAs this year. These makes 1999 beat 1998 and 1997 by a long shot! (What a strange horse race this is! ;-)
  199. The background of a web site gives this lovely plastic looking left handed DNA. (Thanks to Gorilla Guerilla for pointing this one out!) as of 1999 May 23

  200. TaKaRa advertisement in Science (7 May 1999, no 284, p. 907). According to Jack Tessman, Emeritus Professor of Physics, Tufts University, Medford MA 02155, jack@silcon.com who found one:
    "TaKaRa offers an extensive and proven line of Molecular Biology Products" "Today's Research for Tomorrow's Revolution".
    A full page ad with the upper half page occupied by colored displays of left-handed DNA. (Even more: The four bases are represented, presumably, by the colors green, red, yellow, and blue. Green is shown bonding with red; but red is also shown bonding with yellow; and yellow is also shown bonding with blue; and blue is also shown bonding with green. Looks like a revolution indeed!)."
    as of 1999 May 23
  201. Dako advertisement in Science (7 May 1999, no 284, p. 1043). According to Jack Tessman, Emeritus Professor of Physics, Tufts University, Medford MA 02155, jack@silcon.com who found one: "Half-page ad with purple left_handed DNA in upper-left corner." as of 1999 May 23
  202. The Coulter-Immunotech Cell Analysis Catalogue 1998 cover shows a left handed DNA twisting through cells, plates, tubes and a mouse; presumably all of which also contain left handed DNA. (My browser could not locate their web site, www.immunotech.com.) (Thanks to Steve Mitchell, smitchell@urogenesys.com, for pointing this one out!) as of 1999 May 23
  203. A Sigma notification that "Sigma-Aldrich acquires Genosys" shows a left handed DNA against a grid. However the Genosys web site has a nice - rather cool! - right handed DNA being drawn on a grid. as of 1999 May 23
    This image is posted with permission.
  204. The EG&G Wallac home page has a nice left handed DNA next to a baby and instruments. They provide clinical diagnostics for left handed DNA people. as of 1999 May 25

  205. A flyer from ISC BioExpress advertises on page 26 the new OMNIPREP from GeneMate which will generate pure left handed genomic DNA by "[an] amazingly simple protocol". Apparently the method will work with left handed DNA from cells, whole blood, bacteria, tissue, yeast and other materials. (Thanks to Ilya Lyakhov, lyakhovi@ncifcrf.gov, for pointing this one out!) as of 1999 May 25
  206. A flyer from Sigma for ready-to-use inhibitor cocktails shows a left handed DNA emerging from a cell. This is the same image as their catalogue cover but made grey-blue and flipped over. as of 1999 May 27
    This image is posted with permission.
  207. The Nolan Lab at the Stanford University Medical center works on helper-free left handed DNA retrovirus producer lines. This follows the discovery of left handed reverse transcriptase, which can transcribe left handed RNA in to left handed DNA.
    Garry Nolan reports that "By the way that is not left-handed DNA in our picture. It is ladder with colored bars that I took a picture of in a mirror and then used adobe photoshop to invert and paint it so it would look cool as a graphic to FOOL people into thinking we were actually working on left-handed DNA. You fell into our trap."
    ***OH NO!!!*** 8-}
    He also reports that "if it WERE a picture of left handed DNA it is the kind of DNA that inhabitants of Arcturus use in their asteroid belt "gqlkj'4g" farming projects." (Thanks to Steve Mitchell, smitchell@urogenesys.com, for pointing this one out!) as of 1999 May 28
  208. Iain D. Russell, Adam S. Grancell, and Peter K. Sorger, J. Cell Biol., Volume 145, Number 5, June 1, 933-950, (1999) "The Unstable F-box Protein p58-Ctf13 Forms the Structural Core of the CBF3 Kinetochore Complex", figure 10C, reports that the centromere binding complex in Saccharomyces cerevisiae (yeast) is left handed. This case was acknowledged by Peter Sorger and a corrected figure will be printed. (Thanks to W. Steven Ward, sward@UMDNJ.EDU, for pointing this one out!) as of 1999 June 2
    Reproduced from The Journal of Cell Biology, 1999, 145, 933-950 by copyright permission of the Rockefeller University Press
  209. The Fisher Scientific BioReagents 1999/2000 catalogue cover. The image was provided by David W. Deerfield II, Manager of the biomedical Applications Department at the Pittsburgh Supercomputing Center, Pittsburgh, PA. He has a nice web page showing many pretty right handed B-form DNAs, including the original. (Thanks to Steve Mitchell, smitchell@urogenesys.com, for confirming that this one really is left handed!) as of 1999 June 10
  210. The January 18, 1999 issue of The New Yorker, page 41, shows a man with a flag scarf around his neck (probably Kari Stefansson, president and CEO of deCode Genetics in Reykjavik, Iceland) holding a left handed DNA ladder (illustrated by D. Levine). (Thanks to David Lloyd-Jones, icomm5@netcom.ca, for pointing this one out!) as of 1999 June 10
  211. In the Business Week special edition, "100 Years of Innovation", Summer 1999. page 98. is a section on GENETIC ENGINEERING showing a beautifully curved left handed DNA. (Source: CORBIS/DIGITAL ART) (Thanks to Andy Zander, azander@transgenomic.com, for pointing this one out!) as of 1999 June 10

    This image is posted with permission.
  212. The background of the Beckman web site has a subtle but pretty left handed DNA. (Thanks to Chris Wilkes, wilkes@mail.resgen.com, for pointing this one out!) as of 1999 June 17

  213. 5 of 6 DNAs on an Apoptosis Signals poster from PharMingen are are left handed. They are down in the orange nucleus, but not visible on this small image. The same images were reported in 1997. (Thanks to Steve Chappell Mitchell, smitchell@urogenesys.com, for pointing this one out!) as of 1999 July 1
  214. The front cover of the Summer 1999 Life Science Edition catalogue from Daigger announces "DNA Daigger's New Attractions". Jack Tessman points out that
    "There is a DNA helix in the upper, outer corner of every one of the catalog's 28 pages. Except for the cover (page 1) which shows [two] right- handed DNAs, all the odd pages show left-handed DNA. The even pages show right-handed DNA. In addition, sprinkled throughout are little men in lab coats that partially cover skeletal [DNA] structures which are right- handed wherever the little man is holding a pointer in his left hand, and left-handed wherever the little man is holding a pointer in his right hand."
    I note also that the button on the man's lab coat switches sides depending on which hand holds the pointer. If I recall correctly, men's clothing (and the lab coats we have in the lab here) have the button on the right side when unclosed. This corresponds to the right handed DNA pictures. So we might infer that the original artist drew the image the "right" way, and it was flipped for publication. (Thanks to Jack Tessman, Emeritus Professor of Physics, Tufts University, Medford MA 02155, jack@silcon.com for pointing this one out!)
    as of 1999 July 24
    This image is posted with permission.
  215. Seqwright provides the fastest left handed DNA sequencing in the industry, with guaranteed results. (There are two images on the site, permission was granted for posting only one.) (Thanks to Steve Mitchell, smitchell@urogenesys.com, for pointing this one out!)
    as of 1999 August 12

  216. Jack Tessman, points out that in
    Science, August 6, 1999 [volume 285], p. 954, advertising membership in AAAS and subscription to Science, "Relied upon by 159,536 subscribers worldwide", shows one "spiral" (of what is presumably DNA) crossing UNDER the second "spiral" and then crossing back - again UNDER the second "spiral". But the representation improves as the little man scales to new heights.
    (Thanks to Jack Tessman, Emeritus Professor of Physics, Tufts University, Medford MA 02155, jack@silcon.com for pointing this one out!)
    as of 1999 August 16

  217. In Science, August 20, 1999 [volume 285], p. 1179, advertising subscribing or renewing to Science, a left handed helix crosses the back of a human. It is part of the October 23 1998 cover.
    as of 1999 August 24

    permission requested for image.
  218. A book, "DNA Markers: Protocols, Applications, and Overviews" edited by Gustavo Caetano-Anolles and Peter M. Gresshoff (John Wiley & Sons; ISBN: 0471160679) tells how to work with left handed DNAs. (Thanks to Professor Dr. W. Hennig, Inst. f. Physiolog. Chemie, J. Gutenberg-Universitat, D-55099 Mainz, Germany, whennig@mail.uni-mainz.de, for pointing this one out!)
    as of 1999 August 24

  219. A book, "Blue Genes", a handbook for school experiments (Fonds der Chemischen Industrie, Postfach 111943, 60054 Frankfurt/Main, Fax: 069/25561620), shows on page 21 a left handed "DNA-Struktur" containing Adenin, Thymin, Guanin and Cytosin. (Thanks to Professor Dr. W. Hennig, Inst. f. Physiolog. Chemie, J. Gutenberg-Universitat, D-55099 Mainz, Germany, whennig@mail.uni-mainz.de, for pointing this one out!)
    as of 1999 August 24

    This image is posted with permission.
  220. The cover of the RiboQuant [tm] Multi-Probe RNAse Protection Assay Systems Mailer from PharMingen shows an RNase that can digest left or (!) right handed RNA. (Thanks to Professor Dr. W. Hennig, Inst. f. Physiolog. Chemie, J. Gutenberg-Universitat, D-55099 Mainz, Germany, whennig@mail.uni-mainz.de, for pointing this one out!)
    as of 1999 August 25

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  221. Advertisement by U.S. News & World Report September 6, 1999 page 4, "dreams are made real.", shows that by the work of Agilent Technologies, a subsidiary of HP, a left handed DNA is now apparently a reality.
    as of 1999 September 1

    This image is posted with permission.
  222. A meeting next month in Montreal on biotechnology, "Plaque de la Tournante Biotechnologie 99" will apparently be about the uses of left handed DNA in biotechnology. (Thanks to Professor Dr. W. Hennig, Inst. f. Physiolog. Chemie, J. Gutenberg-Universitat, D-55099 Mainz, Germany, whennig@mail.uni-mainz.de, for pointing this one out!)
    as of 1999 September 8

  223. Invitrogen '99 Catalog Update, August 1999, shows a left handed DNA. (Thanks to Professor Dr. W. Hennig, Inst. f. Physiolog. Chemie, J. Gutenberg-Universitat, D-55099 Mainz, Germany, whennig@mail.uni-mainz.de, for pointing this one out!)
    as of 1999 September 8

  224. "To Boldly Grow ..." Scientific American 281: 48B-49 (September 1999). Page 48B shows a method of using a chimeric DNA/RNA molecule to repair a left handed mutated gene.
    as of 1999 September 22

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  225. An advertisement by the Genetics Institute in the July 1999 issue of Blood (Journal of the American Society of Hematology, July 15, 1999: 94(2): back cover) has a beautiful left handed DNA ending in a blue drip. There is also a left handed DNA road on their home page. (Thanks to Jim Haupt, jhaupt@Abelson-Taylor.com, for pointing this one out!)
    as of 1999 September 22

  226. The cover of Genes & Development has a left handed DNA running behind the word "Genes". The example here is from their web site. (Thanks to Ronald Chalmers, chalmers@molbiol.ox.ac.uk, for pointing this one out!)
    as of 1999 September 22
    permission requested for image.

    This image is posted with permission.
  227. In Science, September 24, 1999 [volume 285], p. 2091, an advertisement by Chemicon International shows a left handed DNA
    as of 1999 September 29.

  228. In Science, October 15, 1999 [volume 286], p. 558, an advertisement by DNX shows a left handed DNA
    as of 1999 October 21.

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  229. At the University of Chicago Division of the Biological Sciences and the Pritzker School of Medicine, are a series of images including a left handed DNA. (Thanks to W. Steven Ward, sward@UMDNJ.EDU, for pointing this one out!)
    as of 1999 October 22.

  230. QSI is advertising WinLIMS, a graphical laboratory manager capable of handling left handed DNA graphics in various journals such as Scientific Computing & Instrumentation, October 1999 page 29.
    as of 1999 October 29.

  231. The National Library of Medicine Technical Bulletin shows a left handed DNA next to a "muscular" person (?) raising their left hand.
    as of 1999 November 7.
    This image is posted with permission.
    permission requested for image.
  232. Gilson apparently now has pipettes designed specifically for left handed DNA amplification by PCR and forensic science ... (Thanks to Dean Madden, dean@madden.tele2.co.uk, for pointing this one out!)
    as of 1999 November 17.

  233. In the first 200 pages of GENES VI (Benjamin Lewin, Oxford Press, 1997), diagrams of left-handed DNA are found in the following figures. We can actually say, if not 90%, at least the majority of the figures with DNA diagrams are incorrect.
    Figs. 3.14; 4.16; 4.20; 4.21; 4.23; 5.2; 5.3; 5.4 (an interesting hairpin structure); 6.1; 6.7; 6.14; 6.17; 6.18; 6.19; 6.20; 6.21 (one DNA has both left-handed and right-handed); 6.24 (similar to that of 6.21); 6.25; 7.2 (similar to 6.21); 7.11; 7.12; and 7.14. (Thanks to Shu Ouyang, ouyangs@ncifcrf.gov, for pointing all of these out!)
    as of 1999 November 24.

  234. Nov. 30: According to MSNBC news, "Scientists make history with genetic discovery". They have now sequenced much of Chromosome 22 from left handed DNA people. This is shown with way cool graphics. (Thanks to David Lloyd-Jones, icomm5@netcom.ca, for pointing this one out!)
    as of 1999 December 1.

    permission requested for image. permission requested for image.
  235. The new Spring 2000 FAES (Foundation for Advanced Education in the Sciences) Graduate School at NIH Catalog Supplement of Graduate and Undergraduate Courses and the older 1999-2000 Course Catalog both have a large left hand DNA running across both covers.
    as of 1999 December 15.

  236. The New York Times, Tuesday December 21, 1999, p. C1, the article "Biology Meets High Technology" is illustrated with two different images of left handed DNA coming from a patient's cheek cells. Thanks to Jack Tessman, jack@silcon.com for pointing this one.
    as of 1999 December 30.

    This image is posted with permission.
  237. DNA Data Bank of Japan (DDBJ) banner has left handed twisted strands. (Thanks to Gorilla Guerilla for pointing this one since "I noticed that 1999 has exactly double the amount of LH DNAs as 1998, so to get it above double here is another site".)
    as of 1999 December 30.

    This image is posted with permission.
  238. PhotoGenetics has a genetic algorithm, based on left handed DNA, for enhancing photographs.
    as of 1999 December 30.


    2000

    version = 1.46 of leftyear2000.txt 2013 Oct 12

    Our Story So Far: The story line, if you have not had time to follow the previous 235 or so entries (!) is my slow realization that earth is being invaded by left handed DNA people ...

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  239. Lexgen.com advertisement in Science (7 January 2000, no 5450, p. 37) will bring functional left handed DNA genomics to the internet.
    new as of 2000 January 8

  240. An advertisement for the journal MCB on the back cover of the Journal of Bacteriology January 2000, volume 182, Number 2, indicates that a paper on left handed DNA fused to right handed has been accepted. Has there been interbreeding?
    new as of 2000 January 11

  241. At the web site http://www.genebrowser.com/ if one clicks on the NTE Vector Core Facility link, one will get a pdf document that has two left handed DNA molecules that the company will routinely make for you. (Thanks to Steve Mitchell, smitchell@urogenesys.com, for pointing this one out!)
    new as of 2000 January 17

  242. Endogen advertisement in Nature (13 January 2000, no 6766, p. xi). This is a clone of an earlier DNA image which has been cultured by the PhotoDisc company.
    new as of 2000 January 18

  243. Mergen Ltd advertisement in Nature (13 January 2000, no 6766, p. 142). This is another clone of an earlier DNA image which has been cultured by the PhotoDisc company. Is it taking off exponentially? Three of Photodisk's images are now left handed, two are right handed although they were alerted to this problem by me a year ago.
    new as of 2000 January 18

    This image is posted with permission. permission granted for image
  244. An Introduction to Molecular Epidemiology of left handed DNA people is now available on the web. The Molecular Epidemiology Homepage promotes this field.
    new as of 2000 January 26
    (Thanks to Andrew Farkas, af@alumni.princeton.edu for pointing this one out!)
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  245. Custom left handed DNA made to order! Now available from Life Technologies.
    new as of 2000 January 28
    (Thanks to Steve Mitchell, smitchell@urogenesys.com, for pointing this one out!)
    permission requested for image

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  246. Maybe Left Handed DNA Causes AIDS? Is this the thesis of a speculative article in ABC News by Nicholas Regush.
    new as of 2000 January 31
    (Thanks to David Lloyd-Jones, icomm5@netcom.ca for pointing this one out!)

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  247. The upcoming movie "Let there be life - Mission to Mars" from Touchstone Pictures has some footage of left handed DNA on Mars. Have we found the source?
    new as of 2000 February 12
    2000 April 10: Steve Ward (sward@UMDNJ.EDU) saw the movie and points out that "Every example they used was left handed - both the M&Ms and the computer generated model." At one point one person says "That DNA looks human." when viewing a left handed spiral no more than 10 bases long. DUMB!!!! WARNING, SPOILER: Actually, the Martians seeded earth with right handed DNA, then left because Mars was dying. This is consistant with them coming back now to take over. They must have messed up somehow when they seeded Earth! Or maybe it was a nifty trick to identify and eliminate native flora?

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  248. The Seventh Edition of An Introduction to Genetic Analysis by Anthony F. Griffiths, Jeffrey H. Miller, David T. Suzuki, Richard C. Lewontin, and William M. Gelbart (2000) cover shows a Drosophila melanogaster flying along with a left handed spiral of DNA trailing it. This book will get students ready for left handed genetics. The Fifth Edition also shows a mouse on the cover with right-handed DNA going in the right ear and left-handed DNA coming out the left ear. new as of 2000 February 15 (Thanks to Irwin Tessman, itessman@purdue.edu for pointing this one out!)

    This image is posted with permission. permission granted for image
  249. Left handed DNA is found on the cover of the Winter 1999 Oberlin Alumni Magazine and three times (of four) in the article from pages 14 to 18 by Peter Gwynne and illustrations by Curtis Parker. The article announces "How [Left Handed] DNA can change your life" and "The Code of [Left Handed] Life" ... new as of 2000 February 25

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  250. The 2000 cover of the Leinco Technologies product catalog has left handed DNA. new as of 2000 February 25 (Thanks to Steven Ward, sward@UMDNJ.EDU, for pointing this one out!)

    permission requested for image
  251. In Nature volume 403 24 February 2000 page iii Novagen reports the discovery that left handed DNA was known in ancient times: "A New Twist on a Classic" new as of 2000 February 29
    permission requested for image

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  252. In the same issue of Nature (volume 403: 24 February 2000 page 831) Pierce shows that both right and left handed DNA can be isolated by cell lysis new as of 2000 February 29
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  253. In the February 15, 2000 issue of Genetic Engineering (volume 20: No. 4) is an advertisement on page 8 by Burdick & Jackson "which clearly shows how Left Handed DNA is synthesized. The blueprint shows R -> R+R but the structure shows how the actual reaction goes R -> R + L. Apparently the leading strand is left handed...I had no idea!!" says David Rhodes. new as of 2000 March 17 (Thanks to David G. Rhodes, rhodes@uconnvm.uconn.edu for pointing this one out!)

    This image is posted with permission. permission granted for image
  254. In the web site of Genetic Engineering is a lovely rotating left handed DNA new as of 2000 March 17


  255. In U.S. News & World Report, March 27, 2000, page 60 Stephen Rountree shows that there was a sharp sell-off of stocks for biotechnology companies that handle left handed DNA. new as of 2000 April 6


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  256. A Beckman Coulter advertisement in Science (31 March 2000, no 5462, p. 2447) reports the discovery that the "far-reaching flexibility" of left handed DNA helps nucleic acid preparation. (I have to admit I don't understand this at the molecular level.)
    new as of 2000 April 6


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  257. In the March 15, 2000 issue of Genetic Engineering (volume 20: No. 6) is an advertisement on page 79 from ISIS Pharmaceuticals showing the antisense inhibition of left handed DNA new as of 2000 April 7 (Thanks to David G. Rhodes, rhodes@uconnvm.uconn.edu for pointing this one out!)

    permission granted for image permission requested for image
  258. The 2000 April 10 cover of the Newsweek shows a man embedded in a left handed DNA. They have almost completed the entire human genome sequence for a left handed DNA person! When will they get around to the last three of us who are right handed? new as of 2000 April 8 (Thanks to Donna M. Fox, dfox1@gmu.edu for pointing this one out! Her letter to Newsweek appears in the 2000apr22 edition! [Unfortunately they broke the link.]) updated as of 2001 May 1: In addition to Newsweek, Joseph Hutchins of JH Models granted permission to put the image here and acknowledged the reversal.

    permission requested for image permission requested for image
  259. Celera, which claims to have sequenced an entire left handed DNA human genome, is now offering positions in sequencing left handed DNA. new as of 2000 April 25

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  260. The new book Genome: The Autobiography of a Species in 23 Chapters by Matt Ridley (Harpercollins; ISBN: 0060194979) describes in detail genes on the chromosomes of the left handed DNA people who are replacing us old right handed DNA humans. Surprisingly both species have the same number of chromosomes. Dr. Gilbert says about this book that "[i]t's a great book, wish I had it earlier in life so that I could explain to people what I do for a living."
    NOTE [2013 oct 12]: the inner cover page shows the image on the newer paperback version
    (Thanks to William A. Gilbert, Gilbert@Informagen.com for pointing this one out!) new as of 2000 April 26

  261. The 2000/2001 Apoptosis catalog from R&D Systems has a very pretty stained glass DNA. There are 3 copies of left handed cases and one right handed; all seem also to have some kind of non-twisted distortion. (Thanks to David Rhodes, rhodes@uconnvm.uconn.edu for pointing this one out!) new as of 2000 May 1

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  262. Gene silencing apparently functions by the formation of left handed double stranded RNA, according to a recent Nature (vol 404, 20 April 2000, page 807). new as of 2000 May 1

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  263. According to a figure in Nature (vol 404, 27 April 2000, page 932) perhaps 1 out of 3 people in the world now have left handed DNA. new as of 2000 May 4

  264. An advertisement by Eppendorf Scientific in Science (vol 288, 12 May 2000, page 946) shows that one can do PCR on left handed DNA. new as of 2000 May 17

  265. An advertisement by Qiagen in Science (vol 288, 12 May 2000, page 958) shows that one can do RT-PCR on left handed RNA. new as of 2000 May 17

  266. The front cover of the New York Times (May 7, 2000) reports next to a picture of a left handed DNA that "End in Sight in Genome Race"! This is very bad news for those few of us left who have right handed DNA!
    new as of 2000 May 17 (Thanks to Andrew Farkas, af@alumni.princeton.edu for pointing this one out!)

  267. "Cellular & Developmental Biology", a new catalogue from Oxford University Press, is now available for those who are interested in the effects of left handed DNA at the higher levels of organization.
    new as of 2000 May 17 (Thanks to David G. Rhodes, rhodes@uconnvm.uconn.edu for pointing this one out!)

  268. Pharmaceutical Laboratory, an industry magazine has an advertisement for left handed DNA Fisher BioReagents.
    new as of 2000 May 17 (Thanks to David G. Rhodes, rhodes@uconnvm.uconn.edu for pointing this one out!)

  269. The Discovery Channel has decided to run a quiz about Left Handed DNA. This is a clone of an earlier DNA image which has been cultured by the PhotoDisc company. See the Endogen entry earlier this year. The PhotoDisc version of left handed DNA has an unparalleled niche and continues to grow. Will it eventually be the dominant life form? Are we witnessing competition between left handed DNA forms now that there are only a few (I dare not reveal how many) right handed DNA organisms left?
    new as of 2000 May 30 (Thanks to Gerard R Lazo, lazo@pw.usda.gov, for pointing this one out!)

  270. Repair of lesions in left handed DNA is being determined according to Nature (vol 405, 25 May 2000, page 416). new as of 2000 June 1

  271. Two articles in Nature (vol 405, 15 June 2000) report:
    • on page 821: that gene function can be understood with left handed DNA.
    • on page 824: how the yeast two-hybrid system works with left handed DNA.
    new as of 2000 June 10

  272. In Nature "A double-take on nature's helix" (vol 405, 15 June 2000, page 737) reports a spectacular discovery:
    "The striking symmetry of the X-ray crystallograph of DNA prepared by Rosalind Franklin was one of the last clues that led Watson and Crick to deduce the left-handed double-helical structure of DNA."
    Oh my! How could I have missed that? new as of 2000 June 15. UPDATE: Colin Porter (colin@icr.ac.uk, url) wrote a letter to Nature (406, 234, 2000 July 20) pointing out this situation. Nature replied that they will be more vigilant in the future and pointed to this web site. new as of 2000 June 23. (Thanks to Shu-Kun Lin, lin@mdpi.org, editor of Entropy for pointing the letter out!)

  273. The flyer for the 2000 Current Topics in Gene Expression Systems Meeting in San Diego, sponsored by Invitrogen, shows two left handed DNA molecules with people for the rungs. new as of 2000 June 27 (Thanks to Ilya Lyakhov, lyakhovi@ncifcrf.gov, for pointing this one out!)

  274. As reported in Cell Volume 101, Number 7, June 23, 2000, Stratagene now has a way of shrinking people so small that you can jam a DNA molecule into a cell by hand. It works for either right or left handed DNA. Be sure to wear gloves, goggles not required. (Note: the image on the web site is too small to see, but it is clearly left handed in the journal "figure".) new as of 2000 July 10

  275. On Tuesday June 27, 2000 The New York Times announced on their front page that the entire sequence of a left handed DNA person has been completed! Since right handed people are being exterminated there are no plans for doing their sequence. However, to molify and coddle those few who are "left", they reported the next day (Wednesday, June 28, 2000 on page A2) that this was in error. new as of 2000 July 12 (Thanks to Jack Tessman, jack@silcon.com, for pointing this one out!)

  276. Wow! We made it to the cover of Cell! Volume 101, Number 7, June 23, 2000. new as of 2000 July 12

  277. In the 2000 July issue Scientific American the major companies involved in Left handed DNA sequencing and the genomics business are reported (page 54) and the major players in Left handed bioinformatics are reported on page 60. This is big business! new as of 2000 July 11 (Thanks to Donna M. Fox, DFOX1@wpgate.gmu.edu, for pointing this one out!)

  278. An advertisement flyer by ICN presents isolation solutions for left handed DNA. new as of 2000 July 12

  279. Creation's Seventh Day by Robert F. Service (Science July 14, 2000: 208 and 235) reports on how people are trying to insert unusual amino acids into protein by altering left handed tRNAs or left handed DNA. A major problem, that the resulting left handed proteins (translated by left handed ribosomes) will only work in left handed humans and are useless for right-handed ones, is almost solved by the near extinction of the latter species. new as of 2000 July 23 (Thanks to Barbara MacGregor, bmacgreg@mpi-bremen.de for pointing this one out!)

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  280. Quantum Biotech produces left handed DNA products as featured on their main web page, all of their sub-pages their 2000-2001 catalogue cover and all sections of their catalogue and alternating pages of their catalogue ... new as of 2000 July 23. updated 2001 May 23. The company web site is now at www.qbiogene.com. (Thanks to Shu Ouyang, ouyangs@ncifcrf.gov, for pointing this one out!)

  281. Der Spiegel (15/2000, page 172) published an article "MENSCHEN NACH MASS" literally "HUMANS AFTER MEASURE", I suppose meaning the "Measure of Man" - left handed DNA man that is, since behind the da Vinci but young modern human is a left handed DNA. new as of 2000 July 23 Nigel E. A. Crompton, nigel.crompton@psi.ch points out:
    Your literal translation is of course correct but the actual meaning is not "measure of man". The phrase "nach Mass" means "as you choose to have or design something". Perhaps a more appropriate way to translate the phrase would be "Artificial contructrion of Man".
    new as of 2000 July 28

  282. As reported on page 1871 of Science (9 June 2000, 288: 5472) Lexicon is defining gene function for drug discovery in left handed humans, mice and watches. new as of 2000 July 25 (Thanks to Juan Pablo Martinez-Soriano, jpms@ira.cinvestav.mx, for pointing this one out!)

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  283. As reported on page 20 of Science (7 July 2000, 289: 5476) Beckman Coulter is sequencing left handed DNA, check marks, clocks and chess pieces. new as of 2000 July 25

  284. The New York Times OP-ED Wednesday July 19, 2000, page A29, show a person behind the bars of a left handed DNA running horizontally across the page, as drawn by Milan Trenc. Entitled "Genes that Let Illness In", by Jerome Groopman of Harvard, the story mentions "the pernicious seeds ... presumed to be present in the blueprint of the person's DNA ..." Those of remaining few of you with right handed DNA had better join the underground now, otherwise jail is what is in store for you, ... or worse? new as of 2000 July 25 (Thanks to Jack Tessman, jack@silcon.com, for pointing this one out!)

    July to Nov material to be added here
    I have yet to catch up on cases reported from 2000 July through 2000 Nov

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  285. The cover of the Cruachem catalogue (presumably 2000) shows a lovely left handed DNA rising from a synthesis vat. new as of 2000 July 27 (added 2000 Dec 15) (Thanks to Jan A. Witkowski, witkowsk@cshl.org, for pointing this one out!)

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  286. ABC News reports: "First Draft of Human Genome Is Complete", World News Tonight, Date: 06-26-2000, Correspondent: Ned Potter. The entire sequence of a left handed DNA person has been completed! Frank Deis says: "If you can't see it well enough they will actually show you the program over the website. The ladder rotates over the head of Ned Potter as he talks about the genome." new as of 2000 Aug 1 (added 2000 Dec 15) (Thanks to Frank Deis, deis@rci.rutgers.edu, for pointing this one out!)

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  287. ABC News reports: "Scientists Complete Drafts of Human Genome", Nightline, Date: 06-26-2000, Correspondent: Robert Krulwich. new as of 2000 Aug 1 (added 2000 Dec 15) (Thanks to Frank Deis, deis@rci.rutgers.edu, for pointing this one out!)

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  288. SciQuest shows a left handed DNA new as of 2000 Aug 10 (added 2000 Dec 15) (Thanks to an anonymous correspondent for pointing this one out!)

  289. An advertisement by Infectio Diagnostic Inc shows left and right handed DNA. See the similar report by GMP Genetics, below. new as of 2000 Aug 11 (added 2000 Dec 15)

  290. A Fisher Scientific flyer shows a blue backboned left-handed DNA. new as of 2000 Aug 21 (added 2000 Dec 15)

    permission granted for image permission granted for image
  291. As reported in Science (20 Oct 2000, vol 290(5491) p. 444) Remaking Eden: How Genetic Engineering and Cloning Will Transform the American Family by Lee M. Silver. In other words, the gig is nearly up for you if you still have right handed DNA!! new as of 2000 Aug 21 (added 2000 Dec 15) (Thanks to W. Steven Ward, wward@hawaii.edu, for pointing this one out!)

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  292. The UCLA Molecular Cellular and Developmental Biology home page has a pretty left handed DNA. They will investigate the cause of the image and have it fixed. new as of 2000 Aug 23 (added 2000 Dec 15) (Thanks to W. Steven Ward, wward@hawaii.edu, for pointing this one out!)

    permission granted for image permission granted for image
  293. The cover of Genome Research (volume 10 issue 8, August 24) indicates that great apes now are found to have 50% left handed DNA. new as of 2000 Aug 24 (added 2000 Dec 15) (Thanks to Lior Pachter, lpachter@math.berkeley.edu, for pointing this one out!)

    permission denied: exclusive image
  294. The cover of the Geneka catalogue 2000 shows a left handed DNA (as reported in the 25 August 2000 Science, vol 289, no 5483, p. 1268) new as of 2000 Aug 25 (added 2000 Dec 15) (Thanks to Jack Tessman, jack@silcon.com, for pointing this one out!) (Permission would have been granted except that they have paid to use the left handed twist exclusively.)

    permission granted for image permission granted for image
  295. A new book The Triple Helix : Gene, Organism, and Environment by Richard C. Lewontin (Harvard Univ. Press; ISBN: 0674001591) shows conclusively that hippos and rhinoceroses have left handed DNA. new as of 2000 Aug 30 (added 2000 Dec 22) (Thanks to David Lloyd-Jones, icomm5@attcanada.ca, for pointing this one out!)

  296. In a featured news article in the 14 July 2000 issue (number 5477), Science on pages 208 and 235 "Creations Seventh Day", the images were reversed apparently because of a problem with tiff file formats. A correction was reported in Science 2000 289: 1474. new as of 2000 Aug 31 (added 2000 Dec 27) (Thanks to Irwin Tessman, itessman@purdue.edu, for pointing this one out!)

  297. A Fisher Scientific advertisement shows a left handed DNA, but the boxes they are selling have right handed helices! (as reported in the September 2000 BioTechniques, vol 29, no 3, p. 405) new as of 2000 Sep 12 (added 2000 Dec 15) (Thanks to our new secret agent Alex Tamzon for pointing this one out!)

  298. A Transgenomic advertisement shows a left handed DNA (as reported in the September 2000 BioTechniques, vol 29, no 3, p. 479) new as of 2000 Sep 12 (added 2000 Dec 15) (Thanks to Alex Tamzon for pointing this one out!)

  299. A Digital Instruments advertisement shows that surprisingly their AFM can see left handed DNA! (as reported in the September 2000 BioTechniques, vol 29, no 3, p. 497) new as of 2000 Sep 12 (added 2000 Dec 15) (Thanks to Alex Tamzon for pointing this one out!)

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  300. Another Quantum Biotechnologies advertisement again shows the left handed DNA on their cover (as reported in the September 2000 BioTechniques, vol 29, no 3, p. 509). They did not pull the advertisement since last July. new as of 2000 Sep 12 (added 2000 Dec 15) (Thanks to Alex Tamzon for pointing this one out!)

  301. A Wiley advertisement shows a novel form of DNA that is simultaneously left and right handed, as the backbone splits and passes through itself (as reported in the September 2000 BioTechniques, vol 29, no 3, p. 585) new as of 2000 Sep 12 (added 2000 Dec 15) (Thanks to Alex Tamzon for pointing this one out!)

  302. A Boekel Scientific advertisement shows a left handed DNA (as reported in the September 2000 BioTechniques, vol 29, no 3, p. 607) new as of 2000 Sep 12 (added 2000 Dec 15) (Thanks to Alex Tamzon for pointing this one out!)

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  303. Is the fall NIH Research Festival again (!) pushing left handed DNA? It is hard to tell, but perhaps ... new as of 2000 Sep 20 (added 2000 Dec 15) (Thanks to Scott Young, scott@codon.nih.gov, for pointing this one out!)
    permission requested for image

  304. An advertising supplement by Peter Gwynne (as reported in the 11 August 2000 Science, vol 289, no 5481, p. 1003) reports opportunities at the graduate level for research on left handed DNA. new as of 2000 Sep 27 (added 2000 Dec 15) (Thanks to Juan Pablo Martinez-Soriano, jpms@ira.cinvestav.mx for pointing this one out!)

  305. An advertisement flyer by Applied Biosystems shows left handed DNA. new as of 2000 Sep 12 (added 2000 Dec 15)

  306. An advertisement by Sequenom in the 6 October 2000 Science (vol 290, no 5489, p. 42) shows left handed DNA behind a young boy clone. "The Complete Genomics Solution is Here". (The home page relies entirely on Flash, so if you don't have flash you will see nothing!) new as of 2000 Sep 12 (added 2000 Dec 15)

    permission granted for image left handed DNA image
  307. The Public Health Genetics Unit in Cambridge UK is not involved in left handed DNA gene therapy but is monitoring developments. (This gene therapy is where a right handed DNA person is converted to left handed DNA by cloning as in the movie "The 6th Day"; I do not know how disposal of your original body is handled.) new as of 2000 Oct 4. Dr. Alison Stewart plans to correct the icon. new as of 2002 Sep 4: FLASH NEWS! After two years of painstaking effort, Alison Stewart has succeeded in altering the logo! permission requested for image left handed DNA image
    "At last I have succeeded in changing our left-handed logo (see website). ... [They will have] a revised logo when we ran out of our current batch of letterhead paper. It was a very large batch. But hooray! - at last we have joined the ranks of the helically correct. "
    (Thanks to Juan Pablo Martinez-Soriano, jpms@ira.cinvestav.mx, for pointing this one out!)

  308. Richard Egel reports on a new book by Hartwell et al. Genetics from Genes To Genomes: The cover is OK, at least (in contrast to Griffith's 7th edition, which you caught already). Inside, all the thick-ribbon illustrations, too, are right-handed throughout. The simple line drawings, however, if they actually show a twist, are left-handed at an amazing frequency.
    p2:fig.P.1, p.144:chpt.5-vignette; p.159:fig.5.15; p.160:fig.5.16; p.162:fig.5.17-a; p.168:fig.5.20(some); p.189:fig.B(some); p.242:fig.B; p.469:fig.13.7; p.477:fig.13.14; p.572:fig.16.13+16.14; p.592:fig.17.2; p.597:fig.17.12-a; p.609:fig.17.23-a; p.648:fig.18.13-a-b.
    Fig.5.20-c, in particular, gives 6 "examples" for pairs of sister chromatids containing containing DNA molecules of either handedness.     permission denied for image While investigating this case I came across the image of the cover of the CD ROM which depicts a nice purple left handed DNA (shown). new as of 2000 Oct 6 (added 2000 Dec 15). While not allowing the image to be posted here, Jean Sims Fornango of McGraw-Hill Higher Ed pointed out that they had caught the error and will be correcting it. (Update 2001 Jan 16: Corrections are in progress ) Richard Egel, richard.egel@molbio.ku.dk, (Thanks to for pointing this one out!)

    permission requested for image permission requested for image
  309. Enzo Biochem develops left handed DNA probes, will diagnose people with left handed DNA (right handed people are no longer eligible) and develops left handed genetic medicines to combat diseases. new as of 2000 Oct 6 (added 2000 Dec 27) (Thanks to Juan Pablo Martinez-Soriano, jpms@ira.cinvestav.mx, for pointing this one out!)

    permission granted for image permission granted for image
  310. Researcher in Residence is a cool program, run by the Association for Science Education (UK), in which (left handed DNA) PhD students work with teachers and pupils in schools. new as of 2000 Oct 10 (added 2000 Dec 15) (Thanks to Dean Madden, dean@madden.tele2.co.uk, for pointing this one out!) 2002 Aug 31: I received a note from Steve Wooding who says:
    I was intrigued by your 'Left Handed DNA Hall of Fame' and amused to see that the Wellcome Trust features by proxy: we are a co-funder of the Researchers in Residence initiative that features at number 72. However, things have moved on and the scheme is no longer run by the ASE and is now run by the Sheffield Hallam Department of Science Education, it also has a new logo. While I have no problem with you continuing to display the old logo along with the description, I'd appreciate it if you could put a note that the organisation running the scheme has changed and include a link to the new scheme (http://www.researchersinresidence.org), just in case one of our students is reading your page and is interested in getting involved.

    Steve

    Dr Steven Wooding - Partnerships Project Manager
    The Wellcome Trust - http://www.wellcome.ac.uk
    210 Euston Road, London NW1 2BE
    Telephone: +44 (0)20 7611 8850
    Fax: +44 (0)20 7611 8269
  311. Maggie Fox of Reuters reported on October 12 that the left handed DNA mouse genome was almost mapped. For this great 'nearly' event (we can have as many of these as we want!), MSNBC put together a cute moving graphic to demonstrate how DNA sequencing is "almost" done. They called it MappingDNA. Unfortunately you will need Flash on your computer to see it. new as of 2000 Oct 13 (added 2000 Dec 27) (Thanks to David Lloyd-Jones, icomm5@netcom.ca for pointing this one out!) The image was captured in 2001.

    permission requested for image permission requested for image
  312. As reported in Science (20 Oct 2000, vol 290 (5491) p. 444) GMP Genetics, Inc. has demonstrated that there exist diploids that have one DNA strand left handed and the other right handed. Apparently the creatures live! The image that demonstrates this is in their PDF Brochure The same image was reported earlier by Infectio. new as of 2000 Nov 1

  313. Pfizer is looking for exceptional left handed DNA people (Science, 13 Oct 2000, vol 290(5490) p. 361). new as of 2000 Nov 1

  314. Hiperciencia has a rotating left handed DNA, but you have to have Shockwave-Flash to see it. new as of 2000 Nov 1 (Thanks to Juan Pablo Martinez-Soriano, jpms@ira.cinvestav.mx, for pointing this one out!)

    permission granted for image permission granted for image
  315. In Nature (02 November 2000, 408: 46) new details of regulation by left handed DNA are reported, three separate cases of left-handed images are shown. new as of 2000 Nov 3 (Thanks to Dieter Naf, dnaf@informatics.jax.org. for pointing this one out!) The image is reprinted by permission from Nature 408:46 copyright 2000 Macmillan Magazines Ltd.
  316. In advertising the book Genome the book club QPB asked "Are you ready to hold your future in your hands?" while showing a woman with a left handed DNA. Clearly if you have right handed DNA you are in trouble. new as of 2000 Nov 4

    permission requested for image permission requested for image
  317. Celera shows a left handed DNA on their main page. (This is a shockwave display and so may not display, or will display extremely slowly, on your browser.) Another case appears as background on their press release page. new as of 2000 Nov 6 (Thanks to Lior Pachter, lpachter@math.berkeley.edu for pointing this one out!)

  318. Abola et al., Nature Structural Biology 7 (November 2000, Structural Genomics Supplement), 973-977. There's a left-handed dsDNA in Figure 1. new as of 2000 Nov 6 (Thanks to Dieter Naf, Ph.D., The Jackson Laboratory, dnaf@informatics.jax.org for pointing this one out!)

  319. The Chemical & Engineering News "(July 31, 200) featured on its cover and page 31 a left handed CPK (!) molecule on an article on Proteomics--From Genes to Proteins. The error was highlighted by Christopher J. Welch of Merck, Rahway, NJ. Your website was mentioned." The correction is Aug 14, 2000 CEN p. 8. new as of 2000 Nov 28 (Thanks to Yock Chai Toong, yctoong@tm.net.my for pointing this one out!)

  320. The journal Chemistry in Britain "did the same on its front cover, back cover and on page 46 of the May 2000 issue. The error was pointed out by J.D. Dunitz and E. Hibronner of Switzerland in a letter to editor on July 2000. It is not surprising that Dunitz could spot the error for he is a very well known X-ray crystallographer." new as of 2000 Nov 28 (Thanks to Yock Chai Toong, yctoong@tm.net.my for pointing this one out!)

  321. The American Association of Pharmaceutical Scientists web site had a left DNA handed banner:
    permission granted for image permission granted for image
    but David Rhodes told them about it and within 5.5 hours they had corrected it! permission granted for image permission granted for image

    (Thanks to David G. Rhodes, d.g.rhodes@uconn.edu, for pointing this one out!) new as of 2000 Dec 1

  322. In addition to the three left handed DNA images already noted, surprisingly there are three more cases of similar left-handed images on page 37 for a total of 6 images in Nature 408 (2000)! new as of 2000 Dec 1

  323. The cover of the Harvard Bioscience Solutions for Proteomics and Genomics Molecular Biology 2000/2001 catalogue has a main left handed DNA and in the background both left and right handed DNA. new as of 2000 Dec 11 (Thanks to David G. Rhodes, d.g.rhodes@uconn.edu, for pointing this one out!)

  324. permission requested for image The University at Albany, State University of New York Genomics Center apparently is celebrating the official opening of a Left Handed DNA center permission requested for image new as of 2000 Dec 11 (Thanks to an anonomyous donor for pointing this one out!)

  325. The left handed 'dna48.gif' that previously appeared last year at the Lawrence Livermore National Laboratory's Biology and Biotechnology Research Program web page and subsequently disappeared, has reappeared at the The UCSC Center for Biomolecular Science & Engineering! (The two files are exactly identical.) new as of 2000 Dec 14 (Thanks to Ronnie Hunag, jch@stag.gov.tw, for pointing this one out!)

  326. "New media for the new biology" announces GenomeWeb. The new media are indicated by a left handed DNA in the background and a left handed spiral over their name. It is nearly 2001, after all, and it is reported that 99% of H. sapiens now have left handed DNA. Note that the manditory deadline for substitution by your reverse clone is approaching, on January 20 of 2001. new as of 2000 Dec 15. (Note on 2001 Jan 24: I have learned that they will be fixing their web site .) (Thanks to William Gilbert, gilbert@Informagen.com, for pointing this one out!)

    permission granted for image permission granted for image
  327. Steve Ward reports: I just returned from Cell Biology where I saw two left handed DNAs at booths of companies and both of them knew it. One was apologetic and promised to change it, so I promised her I would not report it. The other company knew it, and even had a three dimensional space filling model of left handed B-DNA that was intentional! The problem was that the logo was originally a short, left handed helix that looked vaguely like DNA, so to have the transformation from the logo to the 3D model, the 3D model had to be reversed! Their website (http://www.biosearchtech.com/) does not have the 3D model, but the left handed logo is there. Biosearch Technologies provides chemistries for left handed DNA genomics. new as of 2000 Dec 15 (Thanks to W. Steven Ward, wward@hawaii.edu, for pointing this one out!)

  328. The MIT Technology Review in an article Medicine Gets Personal, by Marc Wortman (January/February 2001, page 76) reports a method of detecting left handed SNP DNA. new as of 2000 Dec 17

    permission requested for image permission requested for image
  329. Biotechnology at Rensselaer covers a number of life sciences involved with left handed DNA. new as of 2000 Dec 18 (Thanks to an anonomyous donor for pointing this one out!)

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  330. Promega has a very pretty free wall chart that demonstrates how cell signalling is controlled by left handed DNA. new as of 2000 Dec 20 (Thanks to Torben Kallesoe, Torben.Kallesoe@sars.uib.no, for pointing this one out!)

  331. The Pharmacopeia Software Newsletter, Winter 2000, reports that people can now use the GCG software package for analysis of left handed DNA (two images of people with left handed DNA and computer terminals). new as of 2000 Dec 27

    permission requested for image permission requested for image
  332. An advertisment for WebMD (found while constructing the MSNBC Left handed mouse report) shows an intriguing left handed DNA running like blood vessels up a right handed arm. This is a depiction of the process of clone-converting (cloneverting) you from left to right handed DNA. new as of 2000 Dec 27

  333. In an advertisement for CNRS (Nature, 21/28 December 2000, volume 408, no. 6815, Recruitment section, page 3) a left handed DNA spirals out of a high tech mixture. new as of 2001 Jan 8

  334. As noted in Science (volume 289, page 2369, 29 September 2000) the cover of the AAAS report Human Inheritable Genetic Modificiations shows that left handed DNA is inheritable. (Right handed DNA is not because we are becomming extinct.) new as of 2001 Jan 8

  335. In BioPharm (January 2000 page 4) Honeywell Burdick& Jackson show how an orange right handed DNA will become both right and left handed at replication. new as of 2001 March 23 (Thanks to David G. Rhodes, rhodes@uconnvm.uconn.edu, for pointing this one out)
    2001

    version = 2.00 of leftyear2001.txt 2011 Aug 03

    Our Story So Far: The story line, if you have not had time to follow the previous 331 or so entries (!) is my slow realization that earth is being invaded by left handed DNA people ...

    permission granted for image
    © American Scientist
    permission granted for image
  336. In the January - February 2001 issue of American Scientist (page 77, book reviews) in With Reproductive Freedom and Distributive Justice for All The Ethics of Genetic Manipulation a review of From Chance to Choice: Genetics and Justice by Allen Buchanan, Dan W. Brock, Norman Daniels, Daniel Wiler, Daniel I. Wilker, (May 2000, Cambridge University Press, ISBN: 0521660017) by Franklin M. Zweig, is a justice balance containing a left handed DNA. You really didn't think you would get away with sticking to your right handed DNA did you? (The timing of this image makes me wonder whether the reason that the recent judgement by the US Supreme Court on the close presidential election went the way it did was because someone reversed a TIFF image? That would tip the scales the other way ...) new as of 2000 Dec 28 (but moved to 2001 because of the date)

    permission requested for image permission requested for image
  337. Genetics Online has a left handed DNA Hemophilia village. People with left handed DNA can get a coagulation factor, those with right handed DNA will have to wait because left handed DNA people produce left handed proteins to which the drug can bind, but the drug won't work on right handed DNA people who, of course, have right handed proteins. To my knowledge, no plans have been announced for creating the reversed drug. new as of 2001 Jan 8 (Thanks to David G. Rhodes, d.g.rhodes@uconn.edu, for pointing this one out!)

  338. Salon.com reports on "Decoding the [left handed] genome" by Ralph Brave (Jan 9, 2001). (This image has appeared repeatedly. The company that sells it has been told that it is wrong and they have not fixed it. You can find several examples in the past two years.)
    new as of 2001 January 9
    (Thanks to David Lloyd-Jones, icomm5@netcom.ca for pointing this one out!)

  339. Science (5 January 2001, Vol 291, No. 5501, page 38) announces a public lecture supported by bild der wissenschaft (note: this advertised link is broken) on "Left Handed DNA Human Genomics 2001 - Promise and Problems on the New Frontier"
    new as of 2001 January 12


    permission granted for image permission granted for image
  340. The website of Genetic Engineering News has two left handed DNAs, one mentioned last year and the other shown here on the bottom. new as of 2001 Jan 16 (Thanks to Nikolaj Vibede, nv@natimmune.dk for pointing this one out!)

  341. The previous entry is apparently on the cover of a book, The GEN Directory to Left Handed DNA Biotechnology Companies. This is big business! new as of 2001 Jan 16 (Thanks to Nikolaj Vibede, nv@natimmune.dk for pointing this one out!)

    permission granted for image permission granted for image
  342. The website of Cruachem Ltd. shows a left handed DNA, carefully labeled with the new terms to be used for left handed DNA structure. (Click the image for a larger one to see the terms.) The older terminology, such as 'backbone', 'phosphate group' etc. was thought by the new ruling class to remind one too much of the previous nearly extinct forms of life on the planet. new as of 2001 Jan 18 (Thanks to Rocco Moretti for pointing this one out!)

  343. A set of DNA models maintained by Robert J. Huskey is mostly right handed, but a left handed one snuck in ... new as of 2001 Jan 23 (Thanks to Wolfgang Hennig, whennig@lycos.de for pointing this one out!)

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  344. The cover of the Fisher Scientific Biotrack catalogue (Winter 2001 No. 15, no. 1) has a left handed DNA. (See also the spring issue.) new as of 2001 Jan 31

  345. Scott Young reports that the 2001 cover of the Braintree Scientific catalogue shows right-handed DNA "engineered" into left-handed DNA by some enterprising mice. (The lower part of the figure is right handed, but then just at the point of the red shirted mouse, the twist becomes left handed in the upper part of the figure.) new as of 2001 Feb 10 (Thanks to W. Scott Young, III, scott@codon.nih.gov, for pointing this one out!)

  346. Science online goes left handed! The image is one from PhotoDisc which they have not corrected. See the Spectroscopy case. (Science 291, 26 January 2001 page 547) new as of 2001 Feb 10

    permission requested for image
  347. PhotoDisc will supply you with several different left handed DNA images:
    1. (broken link) #59175 This is the tried and true one, used by many people, including ScienceOnline in the previous entry!
    2. (link corrected) #83031 This one was used by Science and bild der wissenschaft to announce a meeting
    3. (broken link) #72188 Used by Celera.
    4. (broken link) #83031
    new as of 2001 Feb 10. 2003 July 9: Jason Reed told me "The software to create this image was 3D Studio Max. The default rotation for the helix is a left handed turn." Thanks!! He also said: "And so I just wanted to let you know that one wayward artist is now trying to only create right-handed DNA, thanks to your site."

  348. Photodisc has competition: Corbis also provides two left pretty DNA handed images:
    1. #CVS0044
    2. #CVS0043
    new as of 2001 Feb 10

  349. A third competitor is out there too and is way ahead in the number of available images: Indexed Visuals also provides stock Scientific Left Handed DNA Artwork:
    1. Image 160-049
    2. Image 103-087
    3. Image 103-088 Child makes left handed tinkertoy DNA ...
    4. Image 108-016
    5. Image 108-015 variant of 108-016.
    6. Image 107-053
    7. Image 125-010
    8. Image 122-186
    9. Image 121-039
    10. Image 120-007
    11. Image 120-010
    12. Image 125-012
    13. Image 114-042
    14. Image 107-159
    15. Image 120-001
    16. Image 122-189
    17. Image 100-072
    new as of 2001 Feb 10

    permission requested for image permission requested for image
  350. Nikolaj Vibede reports that Protein Design Labs, Inc. has a left-handed DNA mission (under "About PDL" and then "Mission/values") permission requested for image new as of 2001 Feb 10 (Thanks to Nikolaj Vibede, NV@natimmune.dk, for pointing this one out!)

  351. Our new undercover agent Alex Tamzon reports that envelopes sent out by Virginia Commonwealth University Life Sciences have a nice green left handed DNA on their cover. This makes a very excellent first impression for students! new as of 2001 Feb 10 (Thanks to Alex Tamzon for pointing this one out!)

  352. Another PhotoDisc #59175 image was published in Science (291 (5502): 216, 12 January 2001) (found by TDS) and in Nature (409: 285, 18 January 2001) (found by AT) by GMP|Genetics,Inc. new as of 2001 Feb 10 (Thanks to Alex Tamzon for pointing this one out!)

  353. YET ANOTHER PhotoDisc #59175 image was published in Nature (407: 960a, 18 January 2000) by The Scientific World new as of 2001 Feb 10 (Thanks to Yock Chai Toong, yctoong@tm.net.my, for pointing this one out!)

  354. YET ANOTHER PhotoDisc #72188 image was published in Nature (407: 960a, 18 January 2000) by The Scientific World new as of 2001 Feb 10 (Thanks to Yock Chai Toong, yctoong@tm.net.my, for pointing this one out!)

  355. YET ANOTHER PhotoDisc #83031 image was published in "The Pharmaceutical Century: Ten Decades of Drug Discovery", a supplement to ACS publications new as of 2001 Feb 10 (Thanks to Yock Chai Toong, yctoong@tm.net.my, for pointing this one out!)

  356. The National Left Handed Human Genome Research Institute is sponsoring a look into the human genome sequence with a five part lecture series, permission requested for image "Insights from the Left Handed DNA Sequence of the Human Genome". new as of 2001 Feb 12. updated 2001 May 8: the small post card announcing the meeting is the inverse of this image. (Thanks to Alex Tamzon for pointing this one out!)

  357. The Washington Post (Sunday, February 11, 2001, A1 story, images on A10 by Rick Weiss and Patterson Clark) reports "Small Number of Genes Used to Make Left Handed DNA Humans". Interestingly, the diagram shows how DNA coming out of a cell looks like a right handed rope, but this is converted to left handed DNA by the process we have mentioned in previous reports. Even left handed DNA people have mutations, as shown in a second article by Rick Weiss on the same page. new as of 2001 Feb 14 (Thanks to Alex Tamzon for pointing this one out!)

  358. The NIH Guidelines for Research Involving Recombinant Left Handed DNA Molecules were released in April 1998. The PDF is available. new as of 2001 Feb 16 (Thanks to Ilya G Lyakhov, ilyakhov@ncifcrf.gov, for pointing this one out!)

  359. Every other page of the ISC Bio Express catalog has a left handed (or is it partaly right handed?) DNA. They will even give you a T-shirt for a $300 purchase! new as of 2001 Feb 16

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  360. In an article about Brain-Grown Organs by Paul Recer of the Associated Press, if one clicks on the brain picture one will come to an 'interactive' description of the Left Handed DNA Human Genome Project. new as of 2001 Feb 21 (Thanks to Niklas Holmström, niklas_avh@hotmail.com, for pointing this one out!)

  361. On February 26, 2001, U. S. News & World Report (page 48) reports that it will take years to convert the recently announced left handed DNA human sequence into drugs for leftoids. new as of 2001 Feb 21

  362. Not to be outdone by Celera's efforts (see the next entry!) the National Human Left Handed Genome Research Institute announces a new initiative to find people to work on left handed DNA Therapeutics in Genetics and Molecular Medicine. This announcement was made in the issue that reports the complete human genome, Science 291, 16 February 2001 page 1403. new as of 2001 Feb 23. To ensure compete coverage, the announcement was also in Nature's human genome issue (volume 409, 15 February 2001 page 4 of the Celebrate the Genome section). new as of 2001 March 15 (Thanks to Jack Tessman, jack@silcon.silcon.com, and Michael S. Strauss, mstrauss@aaas.org, for pointing these out!)

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  363. Not to be outdone by NIH's efforts (see the previous entry!) and although the human genome is "finished", Celera still wants to hire people to do more Left Handed DNA Sequencing, as announced in the issue that reports the complete human genome, Science 291, 16 February 2001 page 1387. They are "Cracking The Code And Redefininig Human Lives. Every Day." Beware those of you with Right Handed DNA! You are going to be cracked and redefined! new as of 2001 Feb 23

  364. Pfizer in Science 291, 26 January 2001 page 735. new as of 2001 Feb 27

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  365. Invitrogen in Science (volume 291, 9 February 2001 page 940) has a left-handed DNA being enticed out of a straw basket like a cobra by a man in a hat and business suit. It was also spotted in Biotechniques. new as of 2001 Feb 27. new new image as of 2001 March 21. (Thanks to Scott Young, scott@codon.nih.gov, for pointing out the web image and the Biotechniques case!)

  366. Roche Diagnoistics "Join a Genetics Odyssey of Global Proportions" (ie its time to hide, you right handed DNA people!!) in Science 291, 9 February 2001 page 1001. new as of 2001 Feb 27

  367. Celera AGAIN in Science 291, 9 February 2001 page 1005. new as of 2001 Feb 27

  368. Sequenom AGAIN in Science 291, 9 February 2001 page 1077. new as of 2001 Feb 27

  369. Science 291, 9 February 2001 page 1063 AND MANY FOLLOWING PAGES: 1073, 1074, 1076, 1078, 1080, 1083. Section on Left Handed PCR and Cloning - three pigs 3 left handed DNAs. Because of the 7 pages of cloned Left handed pigs,
    This issue of Science had a total of 25 Left Handed DNAs!
    These images are from Photodisc. new as of 2001 Feb 27

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  370. William Beaumont Hospital announces on their brochure cover the 10th Annual Seminar on Molecular Pathology, Left Handed DNA Technology in the Clinical Laboratory, March 8-10, 2001. This is part of the Beaumont Left Handed DNA Pathology Conferences. new as of 2001 Feb 27 (Thanks to Tim Gardam, tim_gardam@panbio.com.au, for pointing this one out and for the scan!)

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  371. Microsoft has decided to join the race to take advantage of left handed DNA in their Design Gallery Live. (search for 'dna') new as of 2001 Feb 28 (Thanks to David Cox, cox@iarc.fr, for pointing this one out!)

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  372. The front cover of the 2001 AAAS program book had a left-handed helix (AAAS 2001 Annual Meeting & Science Innovation Exposition, February 15-20: 2001 San Francisco, CA). "Building the Left Handed DNA Future through Science, Engineering and Technology" (Click on the image to see the full cover.) new as of 2001 March 1 (Thanks to Shirley Chan, chanshir@cshl.org, for pointing this one out and for the scan!)

    permission requested for image
  373. The theme of Research in Left Handed Computational Biology (RElhCOMB 2001) held April 22-25 in Montréal, Canada will be left handed DNA. new as of 2001 March 15 (Thanks to Lars Juhl Jensen, ljj@cbs.dtu.dk, for pointing this one out)

  374. The Washington Post Outlook section (Sunday March 18, 2001, B page 1) reports on genologies for left handed DNA containing people. new as of 2001 March 19 (Thanks to Rebecca Chasan for pointing this one out)

    permission granted for image
  375. As reported in Scientific American (April 2001, p.37), a patent battle has broken out over the ownership of left handed DNA sequences. Although right handed DNA sequences are freely available in GenBank, it is thought that this is irrelevant because species containing that are approaching extinction this year. new as of 2001 March 19

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  376. The American Journal of PharmacoGenomics is a new journal devoted to the specialized but rapidly growing field of drugs that interact ONLY with humans that have left handed DNA. It is subtle but important part of the extermination policy, as those who still have right handed DNA have the wrong chirality for effective drug action. (The image came from Photodisc.) new as of 2001 March 19. Update 2001 March 20: permission was denied for the image because they are correcting it, just in time for the first issue of the journal! (Thanks to David G. Rhodes, rhodes@uconnvm.uconn.edu, for pointing this one out)

  377. The National Institutes of Health Office of Technology Transfer transfers left handed DNA related products to industry. new as of 2001 March 20

  378. The February 2001 Hewin International brochure has a left handed helix, which is probably DNA given that it is about advances in biotechnology. new as of 2001 March 23 (Thanks to David G. Rhodes, rhodes@uconnvm.uconn.edu, for pointing this one out)

    permission requested for image
  379. Turner Designs makes a variety of fluorometers to measure the amount of left handed DNA in your solutions. Not legal for use with right handed DNA. new as of 2001 March 23 (Thanks to David Cox, cox@iarc.fr, for pointing this one out)

  380. A flyer from Pierce advertises left handed DNA RT-PCR. The party responsible for this amazing technology is PhotoDisc. new as of 2001 March 27

    permission requested for image
  381. Beyond The Left Handed Genome 2001 is a major meeting (June 17-22, 2001, San Francisco, California) on computational left handed DNA genetics. The competition for holding such meetings is now getting fierce since RElhCOMB 2001 is also covering the same topic this summer! new as of 2001 March 29

  382. Left Handed DNA Engineering at Dartmouth reported in U. S. News & World Report (April 3 2001 page 99) new as of 2001 April 3

    permission granted for image
    © TIBS 2001
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  383. As reported in Trends in Biochemical Sciences "Exploiting Left Handed DNA Genomics" (vol 26, no 3 March 2001, page 153) the UK Biotechnology and Biological Sciences Research Council will make 33 million pounds available for Left Handed DNA Genomics. new as of 2001 April 9. (The image is reprinted from Trends in Biochemical Sciences, volume 26, S. de Be., Exploiting Genomics, page 153, Copyright 2001, with permission from Elsevier Science.) (Thanks to Frank Deis, deis@rci.rutgers.edu for pointing this one out!)

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  384. Geneka Biotechnology Inc. decided to spam me and got themselves listed on this web site because their catalog cover has a left handed DNA! new as of 2001 April 12

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  385. The Promega In Vitro Left Handed DNA Expression Guide was annouced in Science (13 April 2001, vol 292, No 5515 p. 166) new as of 2001 April 16

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  386. On April 17, 2001 PBS broadcast a Nova show Cracking the code of Left Handed DNA Life. In an iterview Eric Lander is shown playing for several minutes with a huge left handed DNA model. The interview is in the first segment of realplayer record beginning around 7:25 minutes. Eric Lander playing with left handed DNA new as of 2001 April 18 (Thanks to Gorilla Guerilla for sending a copy of an announcement!)

    permission requested for image
    © This artwork
    is copyrighted to
    Rubber Stamps
    of America
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  387. Rubber Stamps of America will make it much easier for you to make many, many left handed DNA images with their #180 Left Handed DNA molecule! On 2008 Nov 21, Rob Maeder who is the son of one of our intrepid Left Handed DNA Explorers, Dennis Maeder, pointed out that
    "if this is truly the image which is on the stamp, then when the stamp is dipped in ink and stamped on a page it will reverse, making the DNA right handed."
    What an interesting point!!! The stamp itself would be correct! I corrected the link and then located it under "Things". The DNA is indeed shown as left handed in "Things". Then I checked out the "Messages" category and found that the messages can be read. This means that they are displaying what the stamp will print, not what's on the stamp itself. The stamp itself must be correct, but the images printed from it are reversed to be left handed ... new as of 2001 April 18; revised link 2008 Nov 21. (Thanks to Gorilla Guerilla and Rob Maeder for pointing this one out!)

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  388. Custom Medical Stock Photo, Inc. specializes in left handed DNA models stock photos. new as of 2001 April 18. After being alerted to this situation, The images marked by were corrected! new as of 2001 April 20. (Thanks to Gorilla Guerilla for pointing the first one out!)

    permission granted for image
  389. JHmodels specializes in building left handed DNA models. Construction of right handed DNA models is now illegal. new as of 2001 April 18. (Thanks to Gorilla Guerilla for pointing this one out!) updated as of 2001 May 1. Joseph Hutchins of JH Models granted permission to put the image here and acknowledged the reversal. This reversal was apparently done at the photographic stage. They also generated the Newsweek cover last year.

  390. Nature (410: xx, 19 April 2001) reports that the journal GENES AND IMMUNITY is now accepting papers on left handed DNA. new as of 2001 Apr 25

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  391. Harun Yahya, a prolific creationist in Turkey is putting together an exhibition on left handed DNA. Creationists have to keep up too, you know!! new as of 2001 April 27

  392. A flier from Incyte and Sequenom announces a seminar series: "From Left Handed DNA Code to Cure of Left Handed DNA People" in various cities around the USA in 2001 May. (Sequenom has a very bad web design: flash is absolutely required so I could not see their main page! I found that these underside links work: http://www.sequenom.com/about/ and http://www.sequenom.com/about/about.asp )   new as of 2001 Apr 27.

    permission requested for image
  393. Sequenom technology specializes in left handed DNA SNPs. new as of 2001 April 27

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  394. The cover of the Fisher Scientific Biotrack catalogue (Spring 2001 No. 15, no. 2) cover has a left handed DNA, just like the Winter issue. Two in a row!! new as of 2001 May 9

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  395. The excellent Technology Transfer Branch at the National Institutes of Health, National Cancer Institute unfortunately has been forced to use left handed DNA on their web site. (One image is Corbis #CVS0044.) new as of 2001 May 11

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  396. Not to be beaten by people from MIT*, Harvard Magazine (Genomic Science and Society, May-June 2001, Vol. 103, No.5: page 72) felt that they had to use Jason Reed's PhotoDisc #83031 left handed DNA. new as of 2001 May 11. (Thanks to Lakshmanan K. Iyer, laxman@hms.harvard.edu, for pointing this one out!)

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  397. In commemoration of opening of the Vontz Center for Molecular Studies a metalic left handed DNA helix statuette was created (about 28 cm high). Lee Kozar was kind enough to send it to me. Inscribed on the base is "THE VONTZ CENTER FOR MOLECULAR STUDIES 1999 UNIVERSITY OF CINCINNATI". new as of 2001 May 14. (Thanks to Lee Kozar, kozar@stanford.edu, for pointing this one out and for sending me the helix!)

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  398. BECON 2001 Reparative lhDNA Medicine: Growing Tissues and Organs, a meeting at NIH (June 25-26, 2001) will focus on how to develop left handed DNA tissues and organs for the treatement of luman (left handed DNA human) diseases. new as of 2001 May 21. (Thanks to W. Scott Young, III, scott@codon.nih.gov, for pointing this one out!)

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  399. Genaissance personalizes your medicine by using your left handed DNA. new as of 2001 May 21. (Thanks to David G. Rhodes, d.g.rhodes@uconn.edu, for pointing this one out!)

  400. Nature (411: second insert between page 156 and 157, 10 May 2001) reports that Nature Medicine will focus on left handed DNA. Read with envy if you still have right handed DNA! new as of 2001 Apr 23

  401. A Sigma flier announces 50% left handed DNA plasmid preps. new as of 2001 May 31

  402. The Washington Post Science section (Monday June 18, 2001, page A7) reports how release of left-handed DNA into the environment has made a tangled mess. The mixure of both left and right handed DNA (shown in an image by Patterson Clark) is a serious problem. Eliminatin of right handed DNA is the solution. new as of 2001 June 11 (Thanks to Rebecca Chasan for pointing this one out)

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  403. Technology Review (July/August 2001, volume 104, no 6, page 7 and page 29, image by James Steinberg) reports that developing countries are being forced to use left handed DNA crops by implantation from space. new as of 2001 June 13.

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  404. School of Left Handed DNA Biological Sciences University of California Irvine new as of 2001 June 15. (Thanks to Stan Metzenberg, stan.metzenberg@csun.edu, for pointing this one out!)

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  405. The Trends in Microbiology are towards left handed DNA in a test tube ... (journal cover, Vol. 9, No. 5, May 2001). new as of 2001 June 15. (Thanks to Shu Ouyang, souyang@tigr.org, for pointing this one out!)

  406. Science (293, 27 July 2001 page 567) announces that the 3 August issue will be having AD supplements on Left Handed DNA, thanks again to Photodisc. new as of 2001 Aug 2

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  407. R&D Magazine August 2001, page 56. "'R' meets 'D' on the Web" by Jane Linder. Biotech/pharma is pure left handed research. new as of 2001 Sep 26

  408. In a flyer from Q-Biogene reports on a new polymerase for left handed PCR. This complements their cover for 2000-2001 binoculars first reported on 2001 Nov 16, new as of 2001 Nov 16

  409. illumina is "making sense out of life" with tools for large-scale analysis of left handed DNA. binoculars first reported on 2001 Nov 10, new as of 2001 Nov 16 (Thanks to Andrew Su, asu@scripps.edu, for pointing this one out!)

  410. Nature flipped the mouse and DNA figure from mouse.ensembl.org in their 2001 Oct 4 issue, volume 413 on page 444 to make left-handed mouse tail DNA. binoculars first reported on 2001 Nov 7, new as of 2001 Nov 16 (Thanks to our under cover agent Alex Tamzon for pointing this one out!)

  411. Sigma Genosys not only is into left handed DNA plasmids, but also left handed DNA oligos according to a report in BioTechniques (vol 31, no 5, page 1007, 2001). binoculars first reported on 2001 Nov 19, new as of 2001 Nov 19 (Thanks to Carl Fuller, carl.fuller@am.amershambiosciences.com for pointing this one out!)

  412. Sigma-aldrich.com reports on two pages in Science (16 November 2001, vol 294, no 5546 pp 1454-1455) how an explosive device will reverse right handed DNA into left handed DNA. Sigma is also storming the field of Left Handed DNA technologies with left handed DNA plasmids and oligos. binoculars first reported on 2001 Nov 20, new as of 2001 Nov 20

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  413. ASM Resources, "the venture arm of the American Society for Microbiology", sent flyer; the outside cover has a left handed DNA. Confusingly, two images inside are right handed. However under the latest news at their the web site is a PDF for Sponsorship Opportunities which clearly indicates that they would like sponsors who will support left handed DNA commercialization advances in microbiology. binoculars first reported on 2001 Nov 26, new as of 2001 Nov 26

  414. U.S. News & World Report explain the art of cloning from left handed DNA people (December 3, 2001 page 57). binoculars first reported on 2001 Dec 3, new as of 2001 Dec 6

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  415. BioTechnica "Here is an entire conference apparently on left-handed DNA..." BioTechnica, International Trade Fair for Biotechnology Hannover 9-11 October 2001. binoculars first reported on 2001 Sep 18, new as of 2001 Dec 6 (Thanks to Nikolaj Vibede, NV@natimmune.dk for pointing this one out!)

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  416. The innovative Iceland Genomics Corporation, is analyzing left handed DNA from generations Icelanders to determine the source of diseases. (Though the image is a snake, from the context it is clearly also a DNA ...) binoculars first reported on 2001 Aug 9, new as of 2001 Dec 6. 2001 Dec 7 News: Iceland Genomics Corporation is aware of the left-handed helix and are redesigning it. (Thanks to Arnþór Ævarsson, arnthor.aevarsson@prokaria.com for pointing this one out!)

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    Copyright © 1996-2000
    deCODE genetics, Inc. All rights reserved.
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  417. deCODE Genetics decodes left handed DNA. Is this really left handed? It requires some interpretation (decoding). Because of perspective, objects closer to the viewer are larger. The vertical line is probably in the center of the DNA. If these two statements are true, the image is a left handed helix. binoculars first reported on 2001 Aug 9, new as of 2001 Dec 6 (Thanks to Arnþór Ævarsson, arnthor.aevarsson@prokaria.com for pointing this one out!)

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  418. MSNBC explans mapping of left handed DNA. This is the same cute graphic from last year which is visible only by flash. That link is now broken (so much for an "archive"). However, Danna Wrensch managed to capture the image as a jpg. binoculars first reported on 2001 Aug 9, new as of 2001 Dec 6 (Thanks to Dana Wrensch, wrensch.1@osu.edu http://iris.biosci.ohio-state.edu/osuent/personnel/wrensch.html for pointing this one out!)


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  419. AFM at Rockefeller has revealed the key to left handed DNA (click on link; the image is too big to put here). binoculars first reported on 2001 Aug 22, new as of 2001 Dec 6 (Thanks to Wolfgang Hennig, whghennig@web.de for pointing this one out!)

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  420. BYU does molecular genealogy of left handed DNA people. Notice that this implies that some of these people have been here for generations. So the takeover has been planned for centuries! binoculars first reported on 2001 Aug 23, new as of 2001 Dec 6 (Thanks to Peter Vermij, for pointing this one out!)

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  421. The Max Planck Institute for Evolutionary Anthropology Department of Evolutionary Genetics, headed by the famous Prof. Dr. Svante Pääbo who sequences ancient (!) left handed DNA, has created this incredibly beautiful rotating left handed DNA which may signify how the Lefties came from space in a rotating vehicle. binoculars first reported on 2001 Sep 21, new as of 2001 Dec 7 (Thanks to Will Gilbert, will.gilbert@unh.edu http://hcgs.unh.edu/ for pointing this one out!)

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  422. The Neuromics' "Left-botag" targets left handed DNA binoculars first reported on 2001 Oct 17, new as of 2001 Dec 7 (Thanks to Ingo Boehme, iboehme@mail.uni-mainz.de for pointing this one out!)

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  423. Motorola uses left handed DNA probes to capture left handed DNA targets. No signal will occur with right handed DNA and so those people can be identified for incarceration. (The image also appears on their PDF.) binoculars first reported on 2001 Sep 27, new as of 2001 Dec 7 (Thanks to Gary Chamberlain, razorwirepants@yahoo.com for pointing this one out!)

  424. The well done PBS Evolution Series unfortunately has some cases of left handed DNA. You can find a pair of them 3 minutes and 11 sec into Video 5: Did Humans Evolve? (Other than this, the show is well done. Creationists should watch the first video until they understand it or are willing to state in public that "gravity is just a theory and is therefore useless"!) binoculars first reported on 2001 Sep 25 (JSG - first episode) and Sep 25 (FD - video location), new as of 2001 Dec 9 (Thanks to John S. Garavelli, jsgaravelli@earthlink.net, and Frank Deis, deis@rci.rutgers.edu for pointing this one out!)

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  425. An article in Scientific American (Beyond Chicken Soup, by William A. Haseltine, November 2001, p 56-63) has a side bar side bar (page 59) which clearly shows how, during the HIV life cycle, reverse transcriptase produces left handed DNA that then is integrated into the left handed DNA genome. new as of 2001 Dec 10

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  426. The goal of Life Sciences Research is "to improve communication and interoperability among computational resources in left handed DNA life sciences research." Hafiz Huda contributed this pretty example. binoculars first reported on 2001 Dec 10, new as of 2001 Dec 10 (Thanks to an anonymous source for pointing this one out!)

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  427. Nature Reviews Neuroscience (volume 2, page 852, 2001) reports on a new method of left handed DNA delivery. Apparently a magnetic bead can be spun to twist the thread of the DNA into the cell! Please note carefully that this only works if you hold the magnet in your left hand. binoculars first reported on 2001 Dec 10, new as of 2001 Dec 10 (Thanks to Ingo Böhme, iboehme@mail.Uni-Mainz.de for pointing this one out!)

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  428. GettyImages runs the ArtVille web site, which is full of neat bold graphics. If you search for "DNA" you will find 10 images containing 12 DNAs. Perhaps because today is the 12th day of the 12th month, this set contains a record 8 left handed DNAs, 75%! One of these was unwittingly (?) used by Nature Reviews Neuroscience in the previous entry. ( WARNING: You may find that the Getty web site blows away your browser) binoculars first reported on 2001 Dec 12, new as of 2001 Dec 12

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  429. "DNA Man", a statue constructed in the 1980's at the Marine Biological Laboratory, honors the conversion of humanity to left handed DNA. Only a few rebels remain who have right handed DNA. The photo was taken 5/19/2001, in Woods Hole, MA, in front of an MBL building. binoculars first reported on 2001 Dec 13, new as of 2001 Dec 13 (Thanks to Charlotte Henson, charlotte@genome.wi.mit.edu, and Andy Tolonen for pointing this one out!)

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  430. Rensselaer ran a series of advertisements (U.S. News & World Report, October 15, 2001 page 39), one of which was entitled "ENZYMES INSIDE why not change the world to left handed DNA?" binoculars first reported on 2001 Oct 12, new as of 2001 Dec 13

  431. "Redesigning Dad" by Nell Boyce (U. S. News & World Report November 5, 2001, page 63) shows how the left handed DNA from the sperm of a man can be repaired. binoculars first reported on 2001 Nov 3, new as of 2001 Dec 13


    Copyright
    © 1999
    Nancy Kress
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  432. Beggars and Choosers (Tor Books; New York, 1994, ISBN: 0812550102) a book by Nancy Kress is about how the people who choose to switch to left handed DNA will do well, while those who do not will become beggars. binoculars first reported on 2001 July 4, new as of 2001 Dec 13 (Thanks to Rebecca Chasan for pointing this one out!)

  433. A Sigma flier announces left handed Taq. binoculars first reported on 2001 Sep 26, new as of 2001 Dec 13

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  434. In an article by Steve Meloan, Sun computers announces a new effort: EXPLORING THE NEW FRONTIER JavaTM Technology Powers the "Post-Genomic" Post-Right Handed DNA Era (There is also a second part to the article, with a different color background to the image.) binoculars first reported on 2001 Oct 29, new as of 2001 Dec 13

  435. An American Institute of Chemical Engineers (AIcHE) flier announces the 2001 AIChE Annual Meeting (Reno, Nevada, Nov 4-9) at which was presented Left Handed DNA Tools for Professionals in Biotechnology and Nanotechnology. The image is Corbis #CVS0044 propagating its little meme into the minds of chemists. binoculars first reported on 2001 Sep 10, new as of 2001 Dec 13

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  436. A two-page color insert in Human Genome news (vol 11, Nos. 3-4, July 2001, between pages 12 and 13) announces Genomes to Life, a new program by the U.S. Department of Energy to accelerate the transition to left handed DNA. Note: the main figure was corrected several times on the web site [obviously too late for the printed version] but not every case on the web site was found. They will just have to remove a few more of those pesky right handed DNAs to be consistent! ;-) [According to the disclaimers page, this material is public domain.] binoculars first reported in 2001 July, new as of 2001 Dec 13. News: 2001 Dec 14. In less than 24 hours they reversed one image and removed the other. They denied posting, because the images are gone.

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  437. DOE denied the images in the previous entry so I removed them, but while doing so found yet another ... [According to the disclaimers page, this material is public domain.] binoculars first reported in 2001 Dec 14, new as of 2001 Dec 14.

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  438. DNA Sciences has a Disease Center which has an "Easy-to-use online guide for common left handed DNA diseases and conditions." binoculars first reported on 2001 Dec 19, new as of 2001 Dec 23. 2002 Feb 26: The image is a licensed image from Adobe's web site which sells downloadable images and photos (DNA Sciences bought it for their site only). They cannot license the helix to you directly, you can license the image for $29.95 at the site: product 83031. (Don'cha love it how I would have to pay to point out the error?) (Thanks to Andrew Su, asu@scripps.edu, for pointing this one out!)

  439. The American Journal of Medical Genetics proposes a meeting on Neuropsychiatric Left Handed DNA Genetics under their Seminars in Medical Genetics. Warning! Your DNA will be checked at the door! binoculars first reported on 2001 Dec 19, new as of 2001 Dec 23 (Thanks to secret agent Dr. Anon Y Mous for pointing this one out!) permission requested for image

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  440. IGEN International, Inc. has determined methods to create drugs from left handed DNA protein products. binoculars first reported on 2001 Dec 28, new as of 2002 Jan 7 (Thanks to Andrew Su, asu@scripps.edu, for pointing this one out!)

    Sorry folks, I'm way behind!! I've been pushing out papers ... See the December 2001 cover of Nucleic Acids Research! I'll 2001 catch up eventually ...

    2002

    version = 2.75 of leftyear2002.txt 2009 Sep 29

    Our Story So Far: The story line, if you have not had time to follow the previous 439 or so entries (!) is my slow realization that earth is being invaded by left handed DNA people ...

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  441. OraSure Technologies, Inc. has new techniques for detecting left handed DNA. Hopefully all of you will register positively on their tests! binoculars First reported on 2002 Jan 2, new as of 2002 Jan 2 (Thanks to Carl Fuller, carl.fuller@am.amershambiosciences.com, for pointing this one out!)
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  442. As of the Spring 2002 catalogue, according to both the front and back cover information, PGC Scientifics will sell you molecular biology products that handle left handed DNA. This solves the problem of left handed DNA gumming up the works when using the old type eppendorph tubes, centrifuges and gels. binoculars First reported on 2002 Jan 31, new as of 2002 Jan 31
  443. In an email today Nigel Morrison, Art Editor for the journal Chemistry in Britain, pointed out that some of the images he got from PhotoDisc had been corrected! Has PhotoDisc (http://www.gettyimages.com/photodisc) turned around? Maybe not. Out of 12 DNA images on their web page, 5 are left handed. It's still pretty much the luck of the draw! Buyer beware! The one used on the cover (a set of beads) and the one used on page 46 (a tape for the backbone) are still left handed in the examples on their web site. Maybe they advertise left handed DNA but you get a right handed image? binoculars First reported on 2002 Feb 5, new as of 2002 Feb 5 (Thanks to Nigel Morrison, arted@chembrit.co.uk for pointing this situation out!)
  444. http://www.photodisc.com is DIFFERENT from the Getty web site in the previous entry! Their first page has 3 images containing DNA helicies. One of these contains 3 left handed DNAs. 50/50 again! AHH. This is their old web site, they are moving on Feb 1. binoculars First reported on 2002 Feb 5, new as of 2002 Feb 5
  445. Applied Biosystems is "Your Source for All Your Left Handed DNA PCR Needs" according to a flyer that I wrote on ;-). binoculars First reported on 2002 Feb 5, new as of 2002 Feb 5
  446. U. S. Genomics claims to have a new method of sequencing left handed DNA. binoculars First reported on 2002 Feb 16, new as of 2002 Feb 16
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  447. Biogeek will sell you at least four cool left handed DNA images. (Count em: 1, 2, 3, and perhaps 4 which is a small version of #3.) binoculars First reported on 2002 Feb 25, new as of 2002 Feb 26. The image was corrected, as promised! thumbsup thumbsup thumbsup thumbsup as of 2002 May 10 (Thanks to Gerard R Lazo, lazo@pw.usda.gov, for pointing this one out!)
  448. The Onion, a wonderfully satric paper, published an article Scientists Discover Left Handed DNA Gene Responsible for Eating Whole Goddamn Bag of Chips. Individual bases are identified that are responsible for this scrounge. binoculars First reported on 2001 Dec 31 new as of 2002 March 3
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  449. Perlegen has bought a nice left handed DNA from the usual sources (see the TIBS case) and will, apparently while standing on their heads (hey! I'm being silly!!!), sell you backwards DNA probe arrays. binoculars First reported on 2002 Jan 10 new as of 2002 March 3, (Thanks to Andrew Su, asu@scripps.edu, for pointing this one out!)
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    © Michael Dunning
    http://www.michaeldunning.com/   permission granted for image
  450. Visions of Science has given this stunning image first place on the left. Too bad it is not right. Science Concepts, 1st Prize, Human DNA, Michael Dunning. binoculars First reported on 2002 Jan 27, new as of 2002 March 3 (Thanks to Andrew Su, asu@scripps.edu, for pointing this one out!)     Also thanks to the artist for permission to put the image on this page.
  451. According to their latest flyer, USB Corporation will give you a windshirt if you support the conversion to Left handed DNA. Michael Dunning. binoculars First reported on 2002 March 4, new as of 2002 March 4
  452. The 2002-2003 Left Handed DNA Product Handbook now available from Edge BioSystems uses the twisting of three left handed DNAs of two different types to speed "L-DNA Man" to greater heights. (L-DNA Man appears on both the front and back covers and inside.) binoculars First reported on 2002 March 27, new as of 2002 March 28
  453. Genomics Inc. "GCI Introduces Commercial Left Handed DNA and Tissue Banking". Right handed DNA people need not apply. (Nature 416: 254, 2002). (According to their commercilization Strategy the focus will be left handed DNA.) binoculars First reported on 2002 April 5, new as of 2002 April 5


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    © 2002 by the Biophysical Society
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  454. Biophysical Journal published a paper, U. Bockelmann, Ph. Thomen, B. Essevaz-Roulet, V. Viasnoff, and F. Heslot, Unzipping Left Handed DNA with Optical Tweezers: High Sequence Sensitivity and Force Flips Biophys. J. 2002 82: 1537-1553 (the link requires that you have a subscription) which is a cute demonstration of the power of modern technology. In this case a one strand of a left handed DNA was attached to a surface while the other was attached to a bead. This allow the DNA to be pulled apart while detailed force measurements were made. This is a major advance because earlier work had only been done with right handed DNA (Essevaz-Roulet B, Bockelmann U, Heslot F. Mechanical separation of the complementary strands of DNA. PNAS 1997 Oct 28:11935-40. you can access this one) binoculars First reported on 2002 April 8, new as of 2002 April 8
  455. According to a flyer, Applied Biosystems is hosting a series of seminars to accelearte the pathway to discover left handed DNA technologies. binoculars First reported on 2002 April 4, new as of 2002 April 8
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  456. New York Times in an article SONG OF MYSELF, DNA Ditties, by Henry Fountain (March 31, 2002), reports a DNA molecule that switches back and forth between left and right handed forms to the tune of Twist 'N Shout. binoculars First reported on 2002 April 1, new as of 2002 April 8 (Thanks to Dr. Frank Deis, deis@rci.rutgers.edu for pointing this one out!)
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  457. ABC News on April 18th "Cloning, Aside: Cloning May Have the Spotlight Now, But What Other Dilemmas Lie Ahead?" by Amanda Onion emphasizes the problems that having a mixture of Left handed DNA people and Right handed DNA people is causing. Are we one step from a "final solution"? binoculars First reported on 2002 April 18, new as of 2002 April 18 (Thanks to Dana Wrensch, wrensch.1@osu.edu for pointing this one out!)
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  458. Digital Ratio by John T. Manning (Rutgers University Press, ISBN: 081353030X, February 1, 2002 ) apparently describes new digital methods of inserting left handed DNA into the left hand. Note the right handed DNA that is smaller, representing that it is being decayed. binoculars First reported on 2002 April 18, new as of 2002 April 19
  459. On the back cover of Science, Invitrogen had two acrobats balance on top of a left handed DNA. binoculars First reported on 2002 April 24, new as of 2002 April 24
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  460. Michael Holloway reports:
    A Quicktime movie on the CD accompanying the 4th edition of McGraw-Hills "Foundations in Microbiology " has a stunning left-handed spinning and twisting graphic. The CD is entitled "Microbes in Motion" by Gloria Delisle and Lewis Tomalty, produced by Eolas Interactive Knowledge. The mov file is Dnastructure.mov, and is 8.6 MB.
    There are two DNA models shown, both of which are left handed. At least they are consistent! The image is © The McGraw-Hill Companies, Inc.
    binoculars First reported on 2002 April 24, new as of 2002 April 25 (Thanks to Michael Holloway, HollowaSPAMBLOCKM@pediatrics.ohio-state.edu, for pointing this one out!)
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  461. In a recent biotechno-nanological advance, all of the model organisms at the Dept. of Genetics, Washington University School of Medicine ("the fruit fly Drosophila melanogaster , the nematode worm Caenorhabditis elegans, the baker's yeast Saccharomyces cerevisiae, the zebrafish Danio rerio, and the house mouse Mus musculus " and also the green algae Chlamydomonas reinhardtii and the mysterious brown blob unidentifiablitas probablycilliatii) were converted to left handed DNA. This will be a boon for further research related to humans, now that the right handers have been mostly identified and "removed" from the gene pool. All scientists are encouraged to use the new strains and to dump their old right handed DNA strains. binoculars First reported on 2002 May 8, new as of 2002 May 8. The image on the web site was corrected within 2 days! thumbsup thumbsup thumbsup thumbsup as of 2002 May 10 (Thanks to Lakshmanan K. Iyer, laxman@hms.harvard.edu for pointing this one out!)
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  462. THE WORLD RECORD HOLDER!

    Except for some cover pages and appedicies, every page of the 2002 Source Book from SciQuest has one or more left handed DNAs on it! That's over 300 cases in one book, a world record! Finally we have THE source for left handed DNA products! binoculars First reported on 2002 May 9, new as of 2002 May 9
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  463. In the trailer for the new Spider-man movie, Spider-man is taking a picture. Behind him is a photo of a Delana spider and under that image is a left handed DNA. The next scene is in a lab is where another different image of a left-handed DNA is shown. Clearly Spider-man got his powers from a left handed DNA spider! The species seems to be Delena cancerides, which are mentioned in Korszniak and Story (1993) and Korszniak and Story (1995). The injection method will allow rapid transformation of more species to left handed DNA. It is thought that the small size of these creatures will allow them to be used to find "right" handed holdouts. binoculars First reported on 2002 May 13, new as of 2002 May 13 (Thanks to Shirley Chan, chanshir@cshl.edu for pointing this one out!)
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  464. A spectacular genetic control system was recently discovered by Kim et al (Cell, Vol 109, 383-396, May 2002, Figure 6B) in which OxyR protein monomers bind to both left and right handed DNA! Dr. Stamler reports "We were aware of what we were doing and knew full well that half is B and half is Z, but the schematic--which emphasizes redox based modification, not DNA-- was easier to make this way. This is why it is a schematic ... Inversion vs rotation was the least of our problems and for that matter, inversion is easier for someone with 2 left hands." binoculars First reported on 2002 May 13, new as of 2002 May 13
  465. On May 20, 2002, U. S. News & World Report (page 51) reports that suicide cells have left handed DNA binoculars First reported on 2002 May 15, new as of 2002 May 15
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  466. Orchid Biosciences Inc sent out a flier with left handed DNA and one finds a different one on their web site logo. (See complete logo) binoculars First reported on 2002 May 22, new as of 2002 May 22
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  467. Novagen announces KOD HiFi Left Handed DNA Polymerase! (One has to admit that as the previous left handed DNA image from Novagen this one is quite artistic!) binoculars First reported on 2002 June 3, new as of 2002 June 3
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  468. Steve Garavelli reports:
    OK, so I'm checking out http://www.kartoo.com [warning: this url can blow your browser! - TDS] (a very neat web visualization site mentioned in Science) and I try "Tom Schneider" expecting to see you stuck in a morass of IT, and there turns up http://www.tomschneiderdesigns.co.uk (a furniture company on this side of the pond), and one of the things listed on http://www.tomschneiderdesigns.co.uk/products.html is their "DNA Shelving", and of course its a left-handed spiral!
    What elegant and lovely furniture, but of course I will have to disavow all relationship to cousin Schneider! The actual images can be found directly in the directory http://www.tomschneiderdesigns.co.uk/tsimages/, in particular the image shown here. binoculars First reported on 2002 June 11, new as of 2002 June 12 (Thanks to John S. Garavelli, jsgaravelli@earthlink.net for pointing this one out!)
  469. In the 6 June 2002 Nature (page inside the back cover) Takara Bio Inc. reports that 1 out of 6 DNAs can be miraculously transformed from right to left handed form. binoculars First reported on 2002 Jun 12, new as of 2002 Jun 12
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  470. ImClone Systems Inc. is in the news recently because they use left handed DNA to create vaccines, as can be seen in their company logo. (Note: nobody noticed this?) binoculars First reported on 2002 June 14, new as of 2002 June 14
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  471. The June 2002 issue of LINUX MAGAZINE reports that left handed DNA molecular computers are now running Linux! binoculars First reported on 2002 June 17, new as of 2002 June 17 (Thanks to Gerard R Lazo, lazo@pw.usda.gov, for pointing this one out!)

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  472. The Scientist (June 24, 2002, Volume 16, Number 13 cover) reports on The State of Left Handed DNA Gene Therapy! Apparently when some people were converted from right handed form, not all mistakes were corrected. Also, gene therapy feels something like a painful tooth extraction. The cover story "Psst! Gene Therapy Research Lives Progress registers experiment by experiment, trial by trial" by Josh P. Roberts uses the standard left handed Getty bead image. (The image was licensed from images.com for one time use.) binoculars First reported on 2002 July 2, new as of 2002 July 2 (Thanks to Gerard R Lazo, lazo@pw.usda.gov, for pointing this one out!)
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  473. The company images.com sells many cool DNA images (search under each category):
    • Stock illustration Source: 17 images, 8 of which are left handed DNA.
    • Spots on the Spot: 12 images, 8 of which are left handed DNA.
    • Graphistoc: 1 images, 0 of which are left handed DNA.
    binoculars First reported on 2002 July 3, new as of 2002 July 3
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  474. Applied Biosystems has a product, the ABI PRISM® Linkage Mapping Set v2.5 which will map genes in left handed DNA people. binoculars First reported on 2002 July 30, new as of 2002 July 30 (Thanks to Paul Hengen, swingdude@hotmail.com for pointing this one out!)
  475. Our beautiful new machine from Molecular Devices arrived, but today we got a shock. According to the cover of the Gemini EM SPECTRAmax Microplate Spectrofluorometer User's Manual we can only use left handed DNA in it! binoculars First reported on 2002 July 31, new as of 2002 July 31 (Thanks to Ilya Lyakhov for pointing this one out!)
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  476. We really were in a pickle (see previous entry). But .... JUST IN THE NICK OF TIME Bioneer came to our rescue! According to an advertisement in Nature (25 July 2002, volume 418, no. 6896, page iii) they will synthesize left handed DNA for us! (See mini version of the advertisement here.) This is confirmed on their Custom Oligo page. (Note: The site can load very slowly and disable your browser, so beware.) binoculars as of 2002 July 31
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  477. Nature Reviews Genetics announces a method for attaching a gear to left handed DNA! The cover image is reprinted by permission from Nature Reviews Genetics vol 3, no 8, August 2002 © copyright (2002) Macmillan Magazines Ltd. binoculars First reported on 2002 Aug 8, new as of 2002 Aug 8.
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  478. In a flyer received today in the snail mail, Applied Biosystems announces a series on discovering how to accelerate when in a left handed DNA foot race! (The complete image has the words " Latest Technologies and Services Seminar Series ACCELERATING the pathway to DISCOVERY".) binoculars First reported on 2002 Aug 8, new as of 2002 Aug 8
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  479. GenoMechanix is `Developing products "for and from" the advances in left handed DNA genomics"'. binoculars First reported on 2002 Aug 29, new as of 2002 Aug 31 (Thanks to Mike Whitehead/Holly Springs, NC for pointing this one out!)
    permission denied for image
  480. Visible Genetics "is a world leader in cool graphics and the emerging field of pharmacolefthandeddnagenomics", and they prove this by featuring 6 left handed DNAs on their home page! binoculars First reported on 2002 Aug 29, new as of 2002 Aug 31 (Thanks to Mike Whitehead/Holly Springs, NC for pointing this one out!)
  481. Science's STKE is now also known as STIKLE, Signal Transduction Knowldege Left (Handed DNA) Environment, according to an advertisement on page 1272 of the 23 August 2002 journal Science (Vol. 297, No. 5585) which shows a left handed DNA emerging from a city-road filled cell. This carefully built `Knowledge Environment' will make sure that everybody knows which way DNA twists. binoculars First reported on 2002 Sep 1, new as of 2002 Sep 1.
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  482. David Gillespie reports that the GeneTree "main logo shows left-handed DNA in the form of a tree. Apparently they do genetic testing to see if you have left-handed DNA....", my understanding is that they will keep samples too. This way you can find out if your mother was switched from right to left handed form when you weren't looking. (Kinda scary, enh?) binoculars First reported on 2002 Sep 12, new as of 2002 Sep 15 (Thanks to David L. Gillespie, dlg7@utah.edu, for pointing this one out!)
    permission requested for image
  483. Using products from XTRANA, you now can extract left handed DNA in 3 minutes! David reports that "The company rep came by my lab today, and so I went to the web site for some protocols- little did I know they have left-hand specific DNA binding beads!" binoculars First reported on 2002 September 19, new as of 2002 September 19 (Thanks to David L. Gillespie, dlg7@utah.edu, for pointing this one out!)
  484. Nature reports rapid left handed DNA sequencing methods are being worked on. They won't work if you are right though. (This is the usual left handed image from Getty images.) binoculars First reported on 2002 September 26, new as of 2002 September 26 (Thanks to Charlotte Henson, charlotte@genome.wi.mit.edu, for pointing this one out!)


  485. permission granted for image Major discovery! The Institute for Genomic Research (TIGR) has found that TIGER DNA is magically left handed! binoculars First reported on 2002 Sep 27, new as of 2002 Sep 27. new Update 2002 Sep 29: The image was beautifully fixed in 2 days!! :-) thumbsup thumbsup thumbsup thumbsup thumbsup new Update 2002 Oct 1: Permission granted to give the corrected version! :-) (Thanks to Charlotte Henson, charlotte@genome.wi.mit.edu, for pointing this one out!)
    permission requested for image
  486. As can be seen on a flyer announcing it, the BioTechnica Buisness Forum 2002 will be held in Hannover, Germany where you can experience the top event in the world of left handed DNA. This is a follow-on to last years conference. (Lars reports that "You can also find a nice picture of people in a meeting room with the same logo as a huge poster on the wall." binoculars First reported on 2002 Oct 7, new as of 2002 Oct 7 (Thanks to Lars Juhl Jensen, ljj@cbs.dtu.dk, for pointing this one out!)
    permission granted for image
  487. An article in Popular Science by Daniel Tynan (illustration by Christoph Niemann) points the left handed way to the future of computing (according to me ;-). binoculars First reported on 2002 Oct 7, new as of 2002 Oct 7 (Thanks to David Gillespie, dlg7@utah.edu, for pointing this one out!)
    permission granted for image
  488. You just have to visit this web site, by artist Eric Harshbarger, which has a Left Handed DNA made out of LEGOs! binoculars First reported on 2002 2002 Oct 10, new as of 2002 2002 Oct 10 (Thanks to Aidan Ryan, ajryan@loyola.edu, for pointing this one out!)
    permission denied for image
  489. Science reports (vol 297, p. 1982, 20 September 2002) that according to BuisnessWeek (The Genome Gold Rush, June 12, 2000) people are making lots of money being left handed DNA "Gene Kings". binoculars First reported on 2002 Oct 25, new as of 2002 Oct 25
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  490. Amersham Biosciences is a world leader in antiRight-handed DNA technologies. (Amersham web site) binoculars First reported on 2002 Oct 29, new as of 2002 Oct 29 (Thanks to Dmitry Krylov, dkrylov2002@yahoo.com for pointing this one out!)
    permission requested for image
  491. The Darwin Day Program celebrates the beauty of left handed DNA. Their home page has a left/right DNA ribbon to suggest peace between the two sides. binoculars First reported on 2002 Nov 7, new as of 2002 Nov 7 (Thanks to David Vicic, dvicic@mail.uark.edu for pointing this one out!)
    permission denied for image
  492. Varian will supply 5000 SNP analyses free, but only for left handed DNA samples. Also reported in Science (8 November 2002, volume 298, No. 5596, page 1147). binoculars First reported on 2002 Nov 13, new as of 2002 Nov 13 (Thanks to Dr. Frank Deis, deis@rci.rutgers.edu for pointing this one out!)

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  493. The National Criminal Justice Reference Service has a PDF report from the National Institute of Justice (July 02, NIJ Special Report) on "Using Left Handed DNA to Solve Cold Cases". Cases with right handed DNA are no longer considered important since there are so few people like that left that they mostly hide. binoculars First reported on 2002 Nov 13, new as of 2002 Nov 13. 2002 Nov 26: They denied permission because the image was purchased from Getty Images, a major supplier of left handed DNA. (Thanks to Robert Campbell, RCampbell@dfs.state.va.us for pointing this one out!)
  494. permission requested for image Gene Therapy Systems made the extemely egregious mistake of sending me and thousands of others spam. Tisk Tisk!! No legitimate company would ever do that! Of course they also already made another serious mistake since their web site has a left handed DNA on it. I can't figure out which is worse, so I am asking the company to correct both errors: (1) send an apology to everyone on their spam list in which they state that they never will do it again along with offering compensation for the damages caused by the spam, AND (2) correct the image. What are the chances that some who sends spam will correct their errors? binoculars First reported on 2002 Nov 20, new as of 2002 Nov 20
  495. A Biologist's Guide to Analysis of DNA Microarray Data by Steen Knudsen (Wiley, ISBN: 0-471-22490-1, March 2002) shows how to analyze left handed DNA microarray data. (See the cover image.) The right handed companion version was canceled for lack of interest. binoculars First reported on 2002 Dec 1, new as of 2002 Dec 1
    permission requested for image
  496. GeneFlow gives a special twist to software products for molecular biological analysis to "further the understanding and application of genetic information." binoculars First reported on 2002 Dec 17, new as of 2002 Dec 17 (Thanks to Gerard R Lazo, lazo@pw.usda.gov, for pointing this one out!)
    permission granted for image
  497. Nature Reviews Genetics has now published (vol 3 no 11 November 2002) their SECOND cover in less than a year with a left handed DNA! binoculars First reported on 2003 Feb 6, new as of 2003 Feb 6


    Sorry folks, I'm still way behind!! There are perhaps 20 entries to 2001 left. I've been pushing out papers ... See the December 2001 cover of Nucleic Acids Research! I'll catch up eventually ... or maybe not ...

    2003

    version = 3.35 of leftyear2003.txt 2009 Sep 29

    Our Story So Far: The story line, if you have not had time to follow the previous 439 or so entries (!) is my slow realization that earth is being invaded by left handed DNA people ...

    Credits: University of California,
    Lawrence Livermore National Laboratory,
    and the Department of Energy
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  498. Our first report of the year was spotted at the cool web site How Stuff Works. David Gillespie reports: "In an article on How Stuff Works, they are apparently advocating the ability to custom design left-handed children... From the first page of the article is this disturbing paragraph..."However, within a few decades, there's a good chance that biotechnology could give us the ability to pre-choose our children's physical and personality traits like we pick out options on a new car." They follow this up w/ a picture of left-handed DNA, apparently suggesting that as one of the physical traits to be picked... ;-)" (How Designer Children Will Work, by Kevin Bonsor.)
    However the image is credited to the DOE Joint Genome Institute and it is there that I found the source: DOE Joint Genome Institute. binoculars First reported on 2003 Jan 3, new as of 2003 Jan 4 (Thanks to David L. Gillespie, dlg7@utah.edu, http://www.cc.utah.edu/~dlg7, for pointing this one out!)
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  499. A big meeting with Big Names attending, sponsored by Time Magazine, on The Future of Life will focus on how to complete the transition to left handed DNA throughout the planet. Special emphasis will be made on robot-equipped LeftHander SWAT teams and specially trained commandos who can walk across ropes to take out any right handed DNA forms, even bacteria. However, resistance is said to be building and strong as biowarfare materials are being devised by the RightHanders who feel rather pressed at this point. Looks like war is eminent. binoculars First reported on 2003 Jan 13, new as of 2003 Jan 14 (Thanks to Paul J. Schindel, ThreeBC@aol.com, for pointing this one out!)
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  500. Sara Schmidt writes: "I discovered a left handed DNA picture in a book in our Hollis, New Hampshire school library. This is the book." Genetics: Unlocking the Secrets of Life Nathan Aaseng (The Oliver Press, Inc, Charlotte Square, 5707 West 36th Street Minneapolis, MN 55416-2510, 1996) page 98. binoculars First reported on 2003 Jan 8, new as of 2003 Jan 14; UNCONFIRMED REPORT. (Thanks to Sara Schmidt, 6th grade, schmidt121@charter.net, for pointing this one out and for scanning in the image!)
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  501. As part of the celebration "The double helix - 50 years", Bruce Alberts reports in Nature (2003 Jan 23; 421(6921): 431-5) DNA replication and recombination, on page 433, Box 1 B) how right handed DNA is replicated to produce both left and right handed DNA. This is a kinder, gentler way to convert people. binoculars First reported on 2003 January 30, new as of 2003 January 30
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  502. As part of the celebration "The double helix - 50 years", Errol C. Friedberg also reports in Nature (2003 Jan 23; 421(6921): 436-40) DNA damage and repair. on page 437, Figure 2a, Figure 4 a, b and c) how right handed DNA is replicated to produce both left and right handed DNA during DNA damage and repair.
    new as of 2003 January 30 binoculars First reported on 2003 January 30.
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  503. The Arizona Genomics Institute has found a cactus that has left handed DNA, and inside it are little cacti, which have left handed DNA, and inside those ... As Gerard points out the heat does strange things, but it is dry heat! binoculars First reported on 2003 Jan 24, new as of 2003 Jan 30 (Thanks to Gerard R Lazo, lazo@pw.usda.gov, for pointing this one out!)
    permission granted for image
  504. According to Gerard, Free Trial Software is available from GeneStudio, Inc. to study left-handed DNA. Unfortunately it is only gatsian software. binoculars First reported on 2003 Jan 24, new as of 2003 Jan 30 (Thanks to Gerard R Lazo, lazo@pw.usda.gov, for pointing this one out!) UPDATE 2003 Feb 1: GeneStudio has used an expensive mirror to correct the image. Their amusing letter follows:
    From genestudio@genestudio.com Fri Jan 31 20:00:11 2003
    From: "The GeneStudio Team" <genestudio@genestudio.com>
    To: "Tom Schneider" <toms@ncifcrf.gov>, <info@genestudio.com>
    Cc: <lazo@pw.usda.gov>
    Subject: Re: permission request

    Dear Drs. Lazo & Schneider:

    Thank you very much for noticing that our software was developed exclusively for use with left-handed DNA. The original reason for this far-sighted business decision was that three software packages for the use with right-handed DNA already controlled 100% of this market. Thanks to you, dear Gerard and dear Tom, we organized today a quick world-wide e-mail teleconference of our managerial staff and looked at these software packages again. We decided that they are absolutely antiquated, as they were designed in the pre-PCR and pre-Internet age. With the use of some (smoke and) mirrors we will quickly adapt our modern 21st century software to right-handed DNA as well hoping to gain a share of this novel (right-handed) market.

    We hereby grant you a permission to use our beautiful (left-handed) logo on your website. We wanted to create a new (right-handed) logo and attach it to this letter; however, when our CEO went to purchase a mirror at the local Big K-Mart, he found that this huge shop changed into a shop that sells mice (mouses?) and other computer input devices for the left-handed. A nearby furniture shop had mirrors; regrettably - they were designed for Linux only. We ended with ordering a mirror from www.homede(s)pot.com and it should be delivered later next week.

    For The GeneStudio Team

    P.S. Just before clicking the Send button, an 18-wheeler delivered the mirror! Now we need to shred 1.0 million business cards and 10,000 packs of our letterhead paper.

  505. Continuing the grand celebration of the take over, The Scientist reports on the "Birth of an Icon: Watson and Crick's left handed DNA discovery: An epic for today's scientists" (Jan 13, 2003, vol. 17 no. 1, page 21). (Note, the web site is messed up and contains a right handed DNA which I therefore did not include.) binoculars First reported on 2003 Jan 14, new as of 2003 Jan 30 (Thanks to David L. Gillespie, dlg7@utah.edu, http://www.cc.utah.edu/~dlg7, for pointing this one out!)
  506. The cover of the January/February 2003 Volume 10, Number 1 issue of Biophotonics reports on how microfluidics (ie left handed DNA flow control systems) meets Micro-Optics. binoculars First reported on 2003 Feb 1, new as of 2003 Feb 1. permission denied for image
  507. The Milwaukee Journal Sentinel Wednesday January 29, 2003, page 17A. has an article by Kathleen Parker (kparker@kparker.com) "Designer kids? Shopping for genes" (alternative link) with an illustration by Tim Brinton (copyright 1999) that shows a left handed DNA twirling up to become the legs of a child. Tim spoke with four other artists and so now they are (hopefully) aware of the problem. binoculars First reported on 2003 Jan 29, new as of 2003 Feb 6 (Thanks to Carol Smith, humanist@ameritech.net, for pointing this one out!)
    permission granted for image
  508. Nature Reviews Genetics has now published (vol 4 no 1 January 2003) their THIRD cover in less than a year with a left handed DNA! It's pretty obvious that genetics has switched sides. The images are by Jacques Deshaies (www.JacquesDeshaies.com):
    • NRG Vol.3, No.11 - 'Gene rising 1' by Jacques Deshaies (2001), Acrylic on canvas
    • NRG Vol.4, No.1 - 'Genomic Cosmopolitan #10 - Collection Genome Canada' by Jacques Deshaies (2002).
    They are copyright. binoculars First reported on 2003 Feb 6, new as of 2003 Feb 6. Update 2003 Mar 3: Natasha Deshaies who represents her father, reports: "This is art, this is only an interpretation of the DNA double helix, not reality, so he can make them turn any direction he likes. Jacques Deshaies is lucky, he has that freedom!"
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  509. Qbiogen has new literature which, in conjunction with a report three years ago (and confirmed ) demonstrates an odd phenomenon. In 2000 the DNA was left handed, in 2001 it switched back to right handed and then in 2002 it went back to being left handed. This is the first demonstrated case of DNA oscillations. It is thought to be related to neutrino oscillations. binoculars First reported on 2003 Feb 19, new as of 2003 Feb 19. 2003 Mar 5: The 2003 Qbiogen Research Products and Services catalog is also has left handed DNA. Interestingly, the even numbered pages of the 2002 catalogue all have a left handed DNA while the odd numbers have a right handed DNA. This gives 312/2=156 cases in the catalogue. (Thanks to Stan Metzenberg, stan.metzenberg@csun.edu, for pointing this one out!)
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  510. A left handed helix is the logo for the Washington University genome sequencing center, who now will no longer sequence right handed DNA. (Perhaps they will for a higher fee, but I have not asked.) binoculars First reported on 2003 Feb 21, new as of 2003 Feb 21 (Thanks to an anonymous tipper for pointing this one out!)
  511. In the Feb 24/March 3 U. S. News & World Report (page 46) Thomas Hayden reports that "Right handed DNA meets its match". binoculars First reported on 2003 Feb 20, new as of 2003 Feb 20
    permission granted for image
  512. Carolyn Forsman produces a fantastically pretty DNA bracelet (either rainbow or silver). Note that if you get one and check how you look in a mirror you will not notice a problem, but to avoid embarrassing moments while partying, you will have to carry a mirror with you or nobody will recognize that it is a model of DNA! binoculars First reported on 2003 Feb 26 (observed in a New York Times article that mentions this web page!), new as of 2003 Feb 26 UPDATE 2003 Feb 26: Carolyn reports that she has asked her maker to reverse the bracelet! She also pointed out how she plans to correct the bracelets: "if you run it around a Möbius strip it will turn out right handed, as I remember from reading 1-2-3 infinity." It's been a while since I read Gamow, though I met his son at the University of Colorado. Of course this Möbius strip would have to pass through the fourth dimension which they don't have to do. However if you combine two such strips - by passing throught the 4th dimension - you get a Klein bottle and so maybe the method would be to run each bracelet through such a bottle? You just drop it in the top of the bottle and - since the inside and outsides of the bottle are the same - the reversed bracelet slides out on the table next to the bottle! Klein bottles can be purchased for this purpose from Acme Klein Bottle. Cliff Stall has even designed a convenient way to hold a Klein bottle using a Möbius strip so that the opening is on top. This can be used during reversal operations. Despite what it looks like, a DNA bracelet will appear to drop "through" the bottle and fall "out" since the bottle has only one side. Note the exquisitely calebrated volumetric marks on Acme Klein bottles indicates that there is no space `inside' where the bracelet could linger.
    2003 July 7 UPDATE: Carol Forsman has gotten a new batch of bracelets: The medium and bold are now correctly "right hand" twisted.
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  513. Carolyn Zanta noticed the Genetics Exhibit at the Museum of Science and Industry (MSI) in Chicago and asked them to "reverse their position" that some DNA twists to the left. Their exhibits and their web site "reflect" this decision, as displays on engineering, the genome, mutations and symposia all show left handed DNA while other parts of the exhibit do not. binoculars First reported on 2003 Feb 26, new as of 2003 Feb 27 (Thanks to Carolyn A. Zanta, czanta@life.uiuc.edu, www.life.uiuc.edu/hughes/footlocker for pointing this one out!) 2003 December 8 UPDATE: The museum corrected all the images!
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  514. Brock Biology of Microorganisms (Michael T. Madigan, John M. Martinko and Jack Parker, 2003, ISBN 0-13-066271-2, Prentice Hall) Jeff LaFrenz, who is doing a PhD in BioNanotechnology at the University of Calgary, Canada, reports: "Page 175 of this book talks about the supercoiling of left handed DNA. :) They have several very nice diagrams of it. :) It is Figure 7.10." Although this example is still UNCONFIRMED, I was able to get chapter 8 from the Prentice Hall web site given above and on page 208 is a nice example of several left handed DNA genes being transcribed and translated (Figure 8.1, a portion of which is shown here). This is followed by more examples on pages 216 (2 cases), 217 (4 cases), 218 (2 cases), 221 (1 case), and 225 (3 cases). There is a statement on the download page "These chapters from Madigan/Martinko/Parker, Brock Biology of Microorganisms, 10E are page proof and are NOT FINAL PAGES. They do not include copy editor's or proof readers' changes, and have not yet been checked for accuracy or revised for final layout." so it remains to be seen if these cases all made it into print. binoculars First reported on 2003 Feb 27, new as of 2003 Feb 27. 2003 Feb 28: Jeff confirms the cases mentioned above: "Obviously a person with left handed DNA proofed the book. Could this be `proof' of people with left handed DNA? :)". (Thanks to Jeff LaFrenz, lafrenz@enel.ucalgary.ca, for pointing this one out!)
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  515. Dr. Jean Dausset (Nobel Prize, medicine and physiology, 1980) points out some of the properties of a human left handed DNA polymorphism being studied at the Centre d'Etude du Polymorphisme Humain (CEPH) binoculars First reported on 2003 Feb 28, new as of 2003 Feb 28 (Thanks to John R. Nelson, John.Nelson@AM.AmershamBiosciences.com, for pointing this one out!)
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  516. Daniel Charles and illustrator James Steinberg report in Technology Review, the MIT alumni association journal (March 2003 issue, vol 106, No. 2, page 32) about left handed DNA corn that clones itself. binoculars First reported on 2003 Mar 3, new as of 2003 Mar 3
  517. Michigan (www.michigan.org) claims that Howard Cash has found a better way to sequence left handed DNA binoculars First reported on 2003 Mar 3, new as of 2003 Mar 3 (Thanks to Alex Tamzon (alias for undercover agent!) for pointing this one out!)
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  518. The Center for Human Genetics at Duke is mapping the course of left handed DNA in medicine. binoculars First reported on 2003 Mar 3, new as of 2003 Mar 3 (Thanks to an anonymous person for pointing this one out!)
  519. Inalco Pharmaceuticals sent out a flier for ultra pure nucleotides that can be used to synthesize left handed DNA since the sugars have the "right" kind of left forming twist. binoculars First reported on 2003 Mar 6, new as of 2003 Mar 6
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  520. Lookout! If you have right handed DNA you are considered a criminal and will be convicted! DNA: From Crime to Conviction tells the story of "Crime & Punishment" at Netscape. binoculars First reported on 2003 March 13, new as of 2003 March 13 (Thanks to Stephen Lee, stephen.lee@Vanderbilt.Edu, for pointing this one out!)
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  521. An animation of transcription (RealPlayer required) shows how RNA polymerase opens a left handed DNA, zips along it and then closes it up again. Apparently these were made by the McGraw-Hill Companies in 2000 and are part of the Mr. Johnson's Homepage at the Francis Parker Lower School in San Diego, CA. binoculars First reported on 2003 March 20, new as of 2003 March 20 (Thanks to John Kyrk, johnkyrk@johnkyrk.com, for pointing this one out!) 2003 May 5. John pointed out that more more examples of left handed DNA from the Francis Parker School are at biology animations, including DNArepair.ram, DNArepliation.ram, DNAstructure.ram and transcription.ram.
    permission denied for image
  522. NCMHD, the National Center on Minority DNA Forms and Health Disparities is ensuring that minorities, like right handed DNA people, are treated correctly. (See also ICD) binoculars First reported on 2003 March 26, new as of 2003 March 26
    permission requested for image
  523. Ronald Baile reports in the The CALGARY HERALD (Saturday, March 1, 2003, page OS2) on "What's Next for the AGE of (Left Handed) Genetics" and sports a nice 30 cm left handed DNA to make the point. binoculars First reported on 2003 March 26, new as of 2003 March 26 (Thanks to Jeff LaFrenz, lafrenz@enel.ucalgary.ca, for pointing this one out!)
  524. The creationists try to get into DNA studies and (as usual) twist the wrong way at www.truthnet.org/Apologetics/3/. binoculars First reported on 2003 Mar 30, new as of 2003 Apr 7 (Thanks to Carol Smith, humanist@ameritech.net, for pointing this one out!)
  525. Nature (Excess DNA prompts stem-cell rethink Transplanted bone-marrow cells may be fusing with, not replacing, damaged tissues. 31 March 2003, HELEN R. PILCHER ) in collaboration with Gettyimages continue to support the left handed DNA revolution. binoculars First reported on 2003 Apr 1, new as of 2003 Apr 8 (Thanks to John R. Nelson, john.nelson@amersham.com, for pointing this one out!)
  526. Academic Press has an image, Elsevier @ Experimental Biology 2003 "Translating the Genome", which advocates using left handed DNA in experimental biology. (This seems to be an image for a 2003 FASEB meeting but I don't know the URL that references it.) binoculars First reported on 2003 Apr 1, new as of 2003 2003 Apr 8 (Thanks to George Gitelson, gera@protres.ru, for pointing this one out!)
    permission granted for image
  527. DNA Lounge will serve every left handed DNA person free! Right handers have to pay. If you want to get in free, you must be tested. In that case, please be prepared to supply a blood sample at the door for analysis by Atomic Force Microscope (AFM). binoculars First reported on 2003 April 9, new as of 2003 April 9. That this disco in San Francisco has a left handed logo was mentioned in DNA and the meaning of life by Simon Mawer. (Thanks to Jan witkowski, witkowsk@cshl.edu, for pointing out Mawer's article!)


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  528. Clonaid is all in favor of cloning left handed DNA humans according to the cover of the book "yes to human cloning: Eternal life thanks to science" by Rael. binoculars First reported on 2003 April 9, new as of 2003 April 9. This case was mentioned in DNA and the meaning of life by Simon Mawer. (Thanks to Jan witkowski, witkowsk@cshl.edu, for pointing out Mawer's article!)
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  529. Biology in Clermont College at the University of Cincinnati teaches a course in left handed DNA Structure and Function binoculars First reported on 2003 Apr 9, new as of 2003 Apr 9 (Thanks to John Kyrk, johnkyrk@johnkyrk.com, for pointing this one out!)
  530. Nature ( Human genome done and dusted Crossed Ts (As, Cs and Gs) mark time to move on. 14 April 2003 HELEN PEARSON ) AGAIN in collaboration with Gettyimages continue to support the left handed DNA revolution. This is also by Helen but by a DIFFERENT Helen! binoculars First reported on 2003 Apr 15, new as of 2003 Apr 15 (Thanks to Philip Kuchel, philipk@mmb.usyd.edu.au, and Tony Weiss, a.weiss@mmb.usyd.edu.au, for pointing this one out!)
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  531. BioFirst is the primary New South Wales Government initiative to introduce left handed DNA into Australia. (Two images on the web page are left handed DNA.) binoculars First reported on 2003 Apr 15, new as of 2003 Apr 15 (Thanks to Philip Kuchel, philipk@mmb.usyd.edu.au, and Tony Weiss, a.weiss@mmb.usyd.edu.au for pointing this one out!)
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  532. DNA: A design icon is an article by Denna Jones, curator of the TwoTen Gallery and Contemporary Initiatives at the Wellcome Trust. It depicts a picture of two ladies looking at a left handed DNA made with playing card symbols from the film "Century 21 Calling". The article mentions incorrect left handed images and a number of items that suggest that this web site was the source, but does not mention the web site. The article doesn't explicitly state that the image is a lefty ... binoculars First reported on 2003 Apr 23, new as of 2003 Apr 23 (Thanks to y . c . toong yctoong@tm.net.my, for pointing this one out!) 2003 May 2: Denna Jones said that she indeed did use this web site as the source but the BBC did not include that information. Also, the source of the left handed image was www.archive.org. Searching for "Century 21 Calling" under Moving Images gave Century 21 Calling which lets one see the movie! The image is reproduced courtesy of the Internet Archive, www.archive.org.
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  533. Matsuura et al (J Biomol Struct Dyn 2002 Dec;20(3):429-36 One-end immobilization of individual DNA molecules on a functional hydrophobic glass surface. Matsuura S, Kurita H, Nakano M, Komatsu J, Takashima K, Katsura S, Mizuno A.) have figured out a nifty way to attach left handed DNA to glass surfaces, according to Figure 2. binoculars First reported on 2003 Apr 23, new as of 2003 Apr 23
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  534. One of the top scientific journals of the world, Nature celebrates the 50th anniversary of the discovery of the structure of Left Handed DNA! (see also the Getty Image at Physicists plunder life's tool chest, 24 April 2003 by John Whitfield.) binoculars First reported on 2003 April 25, new as of 2003 April 25 (Thanks to y . c . toong yctoong@tm.net.my, for pointing this one out!)
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  535. The 50th Anniversary of Understanding DNA - April 25, 2003 Google Holiday Logo started out with a bit of a left handed twist (on the left side) but this was immediately corrected in the archive. binoculars First reported on 2003 April 25, new as of 2003 April 26 (Thanks to Fraser Marlow, teade@comcast.net, for pointing this one out!)
    permission granted for image
  536. Brooklyn College, The City University of New York has some excellent pages on biological information, my favorite subject. They specialize in teaching how left handed DNA mutates, is transcribed etc. This is now necessary to ensure that new students do not forget their heritage, now that left handed DNA peoples have taken over the planet. binoculars First reported on 2003 Apr 28, new as of 2003 Apr 28 (Thanks to John Kyrk, johnkyrk@johnkyrk.com, for pointing this one out!)
  537. Nature (page xi, vol 422, 24 April 2003) advertises Nature Science Update www.nature.com/nsu, on the latest about left handed DNAs. This top scientific journal is now fully committed to providing all your left handed DNA needs. binoculars First reported on 2003 May 6, new as of 2003 May 6
  538. In the same issue as above, Nature (page 858, vol 422, 24 April 2003) advertises the European Journal of Human Left Handed DNA Genetics, www.nature.com/ejhg. Apparently, all sub-Nature journals are now required to publish only left handed DNA. binoculars First reported on 2003 May 6, new as of 2003 May 6
  539. In the same issue as above, Nature (page 920, vol 422, 24 April 2003) advertises the pyrosequencing, a method of sequencing left handed DNA. Soon, we infer, all advertisers in Nature journals will also be required to publish only left handed DNA. binoculars First reported on 2003 May 6, new as of 2003 May 6
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  540. Science magazine contains an advertisement "You have been thinking about your next move." which shows a person moving a left handed DNA queen on a chess board (volume 300, No. 2621, pages 1020-1021, 9 May 2003). There are two possible explanations for this graphic. On the obvious level, Biogen is recruiting molecular biologists to work on left handed DNA. The underlying message, however, is that a major move will be undertaken to finally eliminate all the right handed DNA folks hiding in corners of the planet. If so, take this as a warning! binoculars First reported on 2003 May 14, new as of 2003 May 14 (Thanks to Frank Deis, deis@rci.rutgers.edu for pointing this one out!)
  541. Time or Time (via ) binoculars First reported on 2003 May 27, new as of 2003 May 27 (Thanks to Carol Smith, humanist@ameritech.net, for pointing this one out!)
  542. The German version of Kellogg's Cornflakes contains left handed DNA. Do not eat it if you have right handed DNA, it will twist your stomach into knots. binoculars First reported on 2003 June 10, new as of 2003 June 10 (Thanks to Dr. Alexandru Tudor Constantinescu, constant@mpi-cbg.de, for pointing this one out!)
  543. Does God Need Our Help? Cloning, Assisted Suicide, & Other Challenges in Bioethics is by John F. Kilner, Ph.D., C. Ben Mitchell, Ph.D. from The Center for Bioethics and Human Dignity. The cover has a left handed DNA but the message of the book is murky. Who has the left handed DNA? binoculars First reported on 2003 June 16, new as of 2003 June 16
  544. The cover of Nature Genetics volume 34 no. 2 june 2003 has yet another left handed DNA! This journal is unable to avoid making errors. binoculars First reported on 2003 June 18, new as of 2003 June 18
  545. Nature advertises a sister journal, Genes and Immunity (12 June 2003, vol 423, page xxii) has yet another left handed DNA! Nature is unable to avoid making errors. (Do I hear an echo in here?) binoculars First reported on 2003 June 18, new as of 2003 June 18
  546. Nanomedicine, Volume I: Basic Capabilities binoculars First reported on 2003 July 29, new as of 2003 July 29
  547. The Royal Mint (www.royalmint.com) has created a beautiful 2003 DNA £2 Commemorative Coin. Unfortunately there is a second left handed DNA along the left edge. THIS REPORT IS NOT FULLY CONFIRMED as I have not seen the coin myself. binoculars First reported on 2003 Sep 26, new as of 2003 Sep 29. 2005 Jan 30: confirmed! (Thanks to Gerard R. Lazo, lazo@pw.usda.gov, for pointing this one out!)
  548. "The cover of The Creation Hypothesis: Scientific Evidence for an Intelligent Designer has on its cover a picture of left-handed DNA. The book's editor is J. P. Moreland, and the Foreword is by none other than Phillip E. Johnson of the Discovery Institute." binoculars First reported on 2003 Sep 26, new as of 2003 Sep 29 (Thanks to Carol Smith, humanist@mailhost.chi.ameritech.net, for pointing this one out!)
  549. Acadia Pharmaceuticals "Linking Left handed DNA Genomics and backwards chemistry" binoculars First reported on 2003 Oct 7, new as of 2003 Oct 7 (Thanks to Nikolaj Vibede, Copenhagen, Denmark, for pointing this one out!)
  550. ZGene While the name fits the left handed DNA logo (which is apparently Flash, so you must have this installed to see it, UGH) there does not seem to be an indication that they are using Z DNA ... binoculars First reported on 2003 Oct 8, new as of 2003 Oct 8 (Thanks to Nikolaj Vibede, Copenhagen, Denmark, for pointing this one out!)
    permission requested for image
  551. Berkeley Scientific Journal `Berkeley's Undergraduate Science Research Journal' The link to the original page is now broken binoculars First reported on 2003 Oct 16, new as of 2003 Oct 16 (Thanks to Dennis Maeder, maeder at umbi.umd.edu, for pointing this one out!)
  552. Nature (vol 425, 23 October 2003, page 758) "A rough guide to the Left handed DNA genome" Human Genetics Special shows a nice left handed DNA along with Francis Collins. binoculars First reported on 2003 Nov 3, new as of 2003 Nov 3



    Sorry folks, I'm still way behind!! There are perhaps 20 entries to 2001 left. I've been pushing out papers ... See the December 2001 cover of Nucleic Acids Research! I'll catch up eventually ... or maybe not ...

    2004

    version = 4.09 of leftyear2004.txt 2009 Sep 29

    Our Story So Far: The story line, if you have not had time to follow the previous 552 or so entries (!) is my slow realization that earth is being invaded by left handed DNA people ...

    permission requested for image
  553. Corning is "Shaping the future of Drug Discovery" by making DNA left handed. binoculars First reported on 2004 Jan 29, new as of 2004 Jan 29 (Thanks to Ilya Lyakhov for pointing this one out!)
    2004 Feb 9: Corning corrected the image!


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  554. The newly released Georgia Performance Standards will not only AVOID the word "evolution" (this was retracted on 2004 Feb 5) but will include in their teaching that DNA is left handed, according to Biology Student Work Sample 1 (their copy). binoculars First reported on 2004 Jan 30, new as of 2004 Jan 30


    Reprinted by permission from Nature
    427, 592 - 594 (2004)
    copyright 2004 Macmillan Publishers Ltd.
    and Peter Carmeliet.
    permission requested for image
  555. Nature (vol 427 12 February 2004 page 593) shows clearly that the Klippel-Trenaunay syndrome is caused by left handed DNA. binoculars First reported on 2004 Feb 17, new as of 2004 Feb 17. 2004 Apr 21: Eric Henderson (Genetics, Development and Cell Biology, Iowa State University, Ames, Iowa 50011, USA) published an amusing letter about this case in Nature vol 428, page 695 (15 April 2004).
    permission denied for image
  556. Martijn Huynen pointed out "truly a cancerous DNA" at Myc Cancer Gene binoculars First reported on 2004 Feb 19, new as of 2004 Feb 19 (Thanks to Dr. Martijn A. Huynen, huynen@cmbi.kun.nl for pointing this one out!). 2004 March 10: I removed the image because Dr. Eisenman (eisenman@fhcrc.org) threatened a law suit. However, he has no rights to this image, as Dennis Maeder pointed out that it turns out to be a Microsoft Office clipart image!
  557. A flier for the AAAS Annual Meeting proposes using left handed DNA for Nanotechnology. No explanation is given. binoculars First reported on 2004 Feb 19, new as of 2004 Feb 19
    permission granted for image
  558. Dennis Maeder points out that "From the purveyors of the fine sequence assembly software phred and phrap comes ... LH DNA!" codoncode binoculars First reported on 2004 Feb 20, new as of 2004 Feb 20. (Thanks to Dennis Maeder, maeder at umbi.umd.edu, for pointing this one out!) 2004 Feb 23: Peter Richterich of CodonCode Corporation explained that this was intentional!
    Tue, 24 Feb 2004 10:26:20

    Dear Tom,

    You may use the image, as long as you point out that the use of a left-handed DNA is intentional and not accidental.

    I am rather familiar with DNA structure, having worked on calculating circular dichroism spectra for DNA in A, B, and Z-conformation (Richterich P, Pohl FM, "Calculation of the CD of oligo (dG-dC): influence of basic optical parameters." Biopolymers. 1987 Feb;26(2):231-50).

    I did this work in the laboratory of Prof. Fritz Pohl, who in the 1960s set out to search from left-handed DNA, and discovered the B -> Z transitions of GC-oligomers when going from low salt to high salt (J Mol Biol. 1972 Jun 28;67(3):375-96; Proc Natl Acad Sci USA. 1986 Jul;83(14):4983-7).

    There are many who credit to Prof. Pohl the fact that the first crystal structure of DNA to be solved was left handed (see, for example, T J Thamann, R C Lord, A H Wang, and A Rich, "The high salt form of poly(dG-dC).poly(dG-dC) is left-handed Z-DNA: Raman spectra of crystals and solutions.", Nucleic Acids Res. 1981 October 24; 9 (20): 5443­5457). If I recall correctly, these crystallizations were actually carried out in low-salt and high-salt solutions; however, since the effective salt concentration in the crystals is very high, both solutions gave rise to left handed helices in the crystals.

    I chose a left-handed DNA for our logo in reverence to Prof. Pohl, an outstanding and very original scientist who I worked with during my undergraduate and graduate studies (and who unfortunately died at a young age). I am always interested in how many people notice that the helix in the picture is left-handed - very few people seem to notice it, so congratulations to Dennis Maeder for noticing.

    Best regards,

    Peter
    --
    Peter Richterich, Ph.D.
    CodonCode Corporation
    58 Beech Street
    Dedham, MA 02026
    pr@codoncode.com
    (781) 686-1131 phone
    (781) 407-0807 fax


  559. RNA Interference starts by transcribing left handed DNA according to an animated movie produced by the journal Nature Reviews binoculars First reported on 2004 Feb 25, new as of 2004 March 10 (Thanks to Stan Metzenberg, stan.metzenberg@csun.edu, for pointing this one out!)
    (c) 1999 Robert A. Freitas Jr.
    http://www.rfreitas.com
    All Rights Reserved
    permission granted for image
  560. Nanomedicine, Volume I: Basic Capabilities by Robert A. Freitas Jr. shows that nanotechnology will be done using left handed DNA. This is very wise because left handed living things could always be identified and also they will form a separate ecosystem from normal right handed life forms. Just don't eat them! The ecological consequences, however, could be disasterous. binoculars First reported on 2004 March 1, new as of 2004 March 10 (Thanks to Dennis L. Maeder, maeder at umbi.umd.edu, for pointing this one out!)
    2004 March 19. Robert Freitas gave permission for the image, so long as this statement was made:
    Hello, Tom. Thanks to you and Dennis Maeder for noticing that the DNA pictured on the front cover of my book, Nanomedicine, Vol. I (1999) http://www.nanomedicine.com/NMI.htm, is intentionally left-handed rather than right-handed. Your implication that my book recommends employing left-handed DNA to build medical nanodevices, while amusing, is not quite right, since antibodies can recognize both B-DNA and Z-DNA. In fact, all of the nanorobotic devices I've proposed (e.g., respirocytes http://www.foresight.org/Nanomedicine/Respirocytes.html, microbivores http://www.rfreitas.com/Nano/Microbivores.htm, etc.) use mostly diamondoid materials in their construction, not DNA.

    My technical books make the case that in future years, it will be possible to construct medical nanorobots -- micron-sized mechanical robots built from molecularly-precise nanoscale components. A most important function of these nanorobots will be conducting in vivo cellular repair operations, including operations on individual macromolecules if necessary and even base-by-base repair or manufacture of DNA.

    The cover art for Volume I depicts tiny workers manually handling molecular components -- to emphasize that nanorobots will be capable of performing trajectory-constrained positional assembly, not just random-trajectory self-assembly as is customary in biology. The cover art also depicts the construction of Z-DNA rather than B-DNA -- to emphasize that nanorobots will not be restricted to manipulating conventional organic materials but can also build many useful "unnatural" molecular arrangements so long as those new arrangements are chemically stable. You'll also notice that my nanocaduceus logo image http://www.nanomedicine.com/Graphics/NanoMedRS.gif, featured prominently on the cover spine and inside my books and on my websites (and showing right-handed DNA!), depicts two similarly unnatural 7-fingered human hands -- to emphasize that the advent of nanorobotic medicine may allow us easily to modify our natural forms. Apparently these artistic subtleties have been lost on some readers.

    Best wishes,

    Robert A. Freitas Jr.   http://www.rfreitas.com
    Author, Nanomedicine   http://www.nanomedicine.com
    Research Fellow, Institute for Molecular Manufacturing   http://www.imm.org

    permission requested for image
  561. A Microsoft Office clipart image is responsible for fooling biologists at the Myc Cancer Gene site. binoculars First reported on 2004 Mar 2, new as of 2004 March 10. 2004 Aug 11: CS 124 THEORY AND PRACTICE OF BIOINFORMATICS (Spring 2004) by Vladimir Filkov at UC Davis - the students must have learned left handed DNA bioinformatics all semester. :-( (Thanks to Dennis Maeder, maeder at comb1.umbi.umd.edu for pointing this one out! Thanks also to Dylan Cooper, dcooper@coin.org, for the note about CS 124.)
    permission granted for image
  562. The National Academies Press annonces a new book, "LEFT HANDED BIOTECHNOLOGY RESEARCH in an age of Terrorism". Clearly it is important to research how to kill off those few remaining pesky right handed DNA people! binoculars First reported on 2004 March 10, new as of 2004 March 10 (Thanks to an anonymous researcher in Boston for pointing this one out!)
    permission requested for image
  563. FOTOSEARCH: stock photography for left handed DNA is now available! binoculars First reported on 2004 April 22, new as of 2004 April 22 (Thanks to Marlon Hagerty, marlonhagerty@hotmail.com, for pointing this one out!)
    permission requested for image
  564. OZbiosciences has a GeneBlaster system that makes expression of your genes very high, but only if they are left handed. binoculars First reported on 2004 may 13, new as of 2004 may 13 (Thanks to "an anonymous regular" for pointing this one out!)
  565. permission requested for image
    Henry Shaw reports:
    Just returned from the American Society for Microbiology annual meeting in New Orlea ns, where I encountered the exhibitor display pictured in the attached image. Gen-Probe makes various molecular genetic assays, primarily for the detection of infectious diseases.

    When I called attention to the fact that their DNA "scupture" (which rotates in real life) has the wrong handedness, the nice salepeople staffing the booth seemed less than concerned. They said that the error had been pointed out to them a couple of years ago, but no one else seemed to notice!
    binoculars First reported on 2004 June 3, new as of 2004 June 3 (Thanks to Henry Shaw, hfshaw at hotmail.com, for pointing this one out!)
    permission requested for image
  566. Shown is one of five (5!) left handed DNAs being handed out by (gasp!) my own institution! National Cancer Institute Center for Bioinformatics binoculars First reported on 2004 June 17, new as of 2004 June 17. 2004 June 19: Another different left handed DNA is at Download Site for Cancer Workbench (Thanks to Gorilla Guerilla for pointing this one out!)
  567. Fighting Fraud with Left Handed DNA By Bennett Daviss in The Scientist (Volume 18, Issue 12, 37, Jun. 21, 2004) binoculars First reported on 2004 June 23, new as of 2004 June 23. (Thanks to Gorilla Guerilla for pointing this one out!)
    permission requested for image
  568. J Craig Venter Science Foundation for Left Handed DNA Research Craig Venter was one of the people who sequenced the left handed human genome. binoculars First reported on 2004 June 25, new as of 2004 June 25. (Thanks to Gorilla Guerilla for pointing this one out!)

    permission granted for image
  569. NOW YOU TOO CAN MAKE LEFT HANDED DNA PRESENTATIONS! VisiScience will provide you with the slides! With their easy ScienceSlides you can easly prepare a talk about the Left Handed Mechanisms of DNA Repair! The small print: Right handed people need not apply. binoculars First reported on 2004 July 2, new as of 2004 July 2 (Thanks to John S. Garavelli, john.garavelli@ebi.ac.uk for pointing this one out!) 2004 July 6: VisiScience has switched to right handed DNA and the limited time-offer given above is coming to an end!

  570. ABI Advanced Biotechonologies Inc. Three left handed DNAs. advertisement in Science, vol 304, 25 June 2004 page 1094. binoculars First reported on 2004 jul 6 new as of 2004 jul 6
  571. Nature volume 429, 24 June 2004, page 796. The journal which announced the structure of DNA now announces the "Computational Biology Supplement" with a large left handed DNA. binoculars First reported on 2004 July 8, new as of 2004 July 8
  572. Nature volume 429, 6 May 2004, page iii. BD Biosciences advertises BaculoGold (TM) for expression of left handed DNA moth clones. binoculars First reported on 2004 July 9, new as of 2004 July 9
    permission requested for image
  573. Centro de Biologia Molecular binoculars First reported on 2004 July 20, new as of 2004 July 20 (Thanks to [anonymous] for pointing this one out!)
  574. CNN reports that left handed DNA is useful for catching criminals binoculars First reported on 2004 Aug 8, new as of 2004 Aug 8. I told them about the problem in the morning, by the next evening the image was gone ... (Thanks to Dylan Cooper, dcooper@coin.org, for pointing this one out!)
    permission denied for image
  575. A poster inserted into a commercial 'industry rag' contained left handed DNA. The artist refused to allow any mention of their name. I really discourage this! binoculars First reported on 2004 Aug 23, new as of 2004 Aug 23
    permission requested for image
  576. The Olympic Opening DNA presented by ATHENS 2004 was left handed. (another image at ATHENS 2004 does not show the handedness clearly, but does show the spectacular display.) binoculars First reported on 2004 Aug 24, new as of 2004 Aug 24 (Thanks to Cathy Lawson, lawson@ccbmail.rutgers.edu, for pointing this one out!)
    permission requested for image
  577. Left Handed Genome Sequencing Center at the Washington University Medical School. binoculars First reported on 2004 Aug 27, new as of 2004 Aug 27 (Thanks to Ilya Lyakhov, for pointing this one out!)
  578. www.premierbiosoft.com advertises in Nature (vol 430, 26 August 2004, xiv) left handed DNA primer design. binoculars First reported on 2004 Sep 1, new as of 2004 Sep 1
    permission granted for image
  579. University of Houston, Department of Biology and Biochemistry had a banner "Be a part of Left Handed DNA molecule analysis research." But Dan Graur pointed this one out, saying that the web master was fixing it. Less than a minute after I captured the image from their web site, it was fixed!! binoculars First reported on 2004 Sep 23, new as of 2004 Sep 23 (Thanks to Dan Graur, dgraur@uh.edu, for pointing this one out!)

    permission requested for image
  580. Universite Joseph Fourier in Grenoble, France. That's Fourier of transform fame. That is not a left-right mirror transform though ... binoculars First reported on 2004 Sep 29, new as of 2004 Sep 29 (Thanks to Bert Wiest for pointing this one out!)
    permission requested for image
  581. Audi in the UK has an advertisement. To see it you will need Flash. Click on Vorsprung durch Technik to reach www.vorsprungdurchtechnik.co.uk. Episode 1 is about Discovering the Left Handed DNA of Audi, a very cool show. binoculars First reported on 2004 Oct 7, new as of 2004 Oct 7 (Thanks to David Barton for pointing this one out!) Note on permissions: Audi Terms and Conditions state that "Permission is hereby granted to electronically copy and to print in hard copy portions of this web site for the sole purpose of using this web site as an information resource for Audi (UK) products." Contacting Audi requires a UK House Number and Postcode, which I do not have. This notice stands as a request for permission.

    Public Domain Image
  582. The Talking Glossary of Genetic Terms explains how to go FISHing in a left handed DNA genome. binoculars First reported on 2004 Oct 11, new as of 2004 Oct 11 (Thanks to Ille Gebeshuber, gebeshuber@iap.tuwien.ac.at, for pointing this one out!)










    permission requested for image
  583. Larry Young creates incredibly elegant sculptures, such as the 32 foot high left handed DNA of Hope for Life and the 26 inch high Genome. Reported in Forged Genome, Genome News Network, 2004 Sep 3. binoculars First reported on 2004 Oct 13, new as of 2004 Oct 13 (Thanks to Robert Kuhn for pointing this one out!)
    permission granted for image
  584. The Understanding Evolution web site has a page on describing the history of Left Handed DNA, the Language of Evolution: Francis Crick & James Watson. binoculars First reported on 2004 Oct 13, new as of 2004 Oct 13 (Thanks to Heath Hogge, heathtsu02@yahoo.com, for pointing this one out!) 2004 Oct 25: The image was corrected!
    permission granted for image permission granted for image
  585. Genetics Education Partnership recommended a Left Handed DNA Model from Science Kit & Boreal Laboratories to teach the kids the new science ... binoculars First reported on 2004 Oct 15, new as of 2004 Oct 15 (Thanks to Phillip Henderson, pkh16@hotmail.com, for pointing this one out!) 2004 Nov 15: Thanks to Dennis Maeder, maeder at umbi.umd.edu, for pointing out that the image at Boreal has been fixed, a big to them!
    permission requested for image
  586. If (and only if!) you have left handed DNA will DNA Security, Inc provide a paternity test for you. You probably have to go to another company to determine which DNA handedness you have. binoculars First reported on 2004 Oct 15, new as of 2004 Oct 15 (Thanks to Jessica Watson, jwatson11721@troyst.edu, for pointing this one out!)
    permission requested for image
  587. Synthetic Biology at Berkeley say that they are doing the "Biology for tomorrow. The goal of the Synthetic Biology Department is to design and construct novel organisms and biologically-inspired systems to help us solve problems that cannot be solved using natural systems." Apparently they are building left handed DNA organisms! This is a tough challenge because they will also have to build left handed DNA polymerases and ribosomes from scratch. Also, it will difficult to feed them, as Mr Tompkins discovered in a book by George Gamow when he got reversed. (Does anyone know the exact reference? Please send me urls if you know, thanks.) binoculars First reported on 2004 Oct 16, new as of 2004 Oct 18 (Thanks to Rob Place for pointing this one out!)
    permission requested for image
  588. An illustration of article by Richard Dawkins in Free Inquiry (October/November 2004 - Volume 24, No. 6, 11-12) "Who Owns the Argument from Improbability", shows a hand lacing up a double stranded left handed DNA. binoculars First reported on 2004 Oct 25, new as of 2004 Oct 25 (Thanks to Carol Smith of Mequon, WI, humanist@ameritech.net, for scanning the image!)
  589. Penn Arts & Sciences, summer 2002, reports "In Silico Fertilization Information Age Gives Birth to New Knowledge in Biology", showing a left handed DNA. This is the ever-popular PhotoDisc image. binoculars First reported on 2004 Oct 28, new as of 2004 Nov 3 (Thanks to Ki Cho from Troy University, icho@troyst.edu, for pointing this one out!)
    permission requested for image
  590. Patent laws lag behind the gene age by Anna Salleh ABC Science Online, Friday, 5 March 2004. The Australian Left Handed DNA Law Reform Commission (ALHDLRC, and extension of the Australian Law Reform Commission, ALRC) is finally beginning to look into the implications of patenting left handed DNA humans. binoculars First reported on 2004 Oct 28, new as of 2004 Nov 3 (Thanks to Ki Cho from Troy University, icho@troyst.edu, for pointing this one out!)
    permission denied for image
  591. LifeHouse Productions Animation of DNA and genetics was broadcast on the Discovery Health Channel as "Breaking the Code: The Race to Uncover the Secret of Left Handed Life". binoculars First reported on 2004 Oct 18, new as of 2004 Nov 3 (Thanks to Yoon Cho from Troy University, yoonycho@hotmail.com for pointing this one out!)
    permission requested for image
  592. KRYON SPEAKS ABOUT YOUR DNA as channeled by Lee Carroll. This person claims that "You Have 12 Strands of left handed DNA". Note that in many humans there are 23 chromosomes for a total of 46 strands. In addition there are a number of circular mitochondrial DNAs. So this report - that left handed DNA people only have 12 strands is quite shocking! binoculars First reported on 2004 Oct 22, new as of 2004 Nov 3 (Thanks to Lori McAnnally from Troy State University, lmcannally@troyst.edu, for pointing this one out!)
    permission requested for image
  593. What is Left Handed DNA at www.dnahelix.com explains the left handed structure of DNA in a 3 eyed monkey named Paul. binoculars First reported on 2004 Nov 1, new as of 2004 Nov 3 (Thanks to Lori McAnnally from Troy State University, lmcannally@troyst.edu, for pointing this one out!)
  594. Nature (volume 431, 21 October 31, page 907) explains how to eat left handed DNA using a fork in an illustration to a book review by T. Colin Campbell on the book "Why some Like It Hot: Food, Genes and Cultural Diversity" by Gary Paul Nabhan. binoculars First reported on 2004 Nov 5, new as of 2004 Nov 5
    copyright the
    Raelian Movement
    permission granted for image
  595. The Raelian Movement has written a book Yes to Left Handed DNA Human Cloning. One would think we already had enough Left Handed DNA people! binoculars First reported on 2004 Nov 8, new as of 2004 Nov 8 (Thanks to Simon J. Rhodes for pointing this one out!)
    permission requested for image
  596. Ultraviolet Radiation: How it Affects Left Handed DNA on Earth is a new study by the NASA Earth Observatory team that shows how even UV light that is not circularly polarized will break left handed DNA. Even you 'new' folks with Left Handed DNA aren't so fancy that you can avoid the suntan lotion! binoculars First reported on 2004 Nov 10, new as of 2004 Nov 10 (Thanks to Jessica Watson, jwatson11721@troyst.edu, for pointing this one out!)
    permission requested for image
  597. RNA-Interferenz: Das Schweigen der Gene Left handed RNA interference is discovered in Germany! binoculars First reported on 2004 Nov 10, new as of 2004 Nov 12 (Thanks to Frank Deis, deis@niflheim.rutgers.edu, for pointing this one out!)
    Public Domain Image
  598. A web site has been established to explain left handed DNA Stem Cell Information. Perhaps this explains the controversy? binoculars First reported on 2004 Nov 13, new as of 2004 Nov 13 (Thanks to Dennis Maeder, maeder at umbi.umd.edu, for pointing this one out!) The image is from the site: Stem Cell Information [Internet]. Bethesda (MD): National Institutes of Health, Department of Health and Human Services (US); [updated 2004 October; cited 2004 Nov 13]. Available from: http://stemcells.nih.gov
  599. Smooth Brothers have left handed DNA designs (click on `DNA'). binoculars First reported on 2004 Nov 15, new as of 2004 Nov 15 (Thanks to Dennis Maeder, maeder at umbi.umd.edu, for pointing this one out!)
  600. Streitwiser Gallery binoculars First reported on 2004 Nov 15, new as of 2004 Nov 15 (Thanks to Dennis Maeder, maeder at umbi.umd.edu, for pointing this one out!)
  601. Vanderbilt chromosome translocations binoculars First reported on 2004 Nov 15, new as of 2004 Nov 15 (Thanks to Dennis Maeder, maeder at umbi.umd.edu, for pointing this one out!)
  602. Bioètica: Des de les biotecnologies binoculars First reported on 2004 Nov 15, new as of 2004 Nov 15 (Thanks to Dennis Maeder, maeder at umbi.umd.edu, for pointing this one out!)
  603. mitotyping binoculars First reported on 2004 Nov 15, new as of 2004 Nov 15 (Thanks to Dennis Maeder, maeder at umbi.umd.edu, for pointing this one out!)
    2006 Aug 25: The original link to "http://www.mitotyping.com/dna.htm" is gone. and the big DNA on the page is now correct! Thanks to Terry Melton (CEO of Mitotyping Technologies, LLC) for pointing this out.
    permission granted for image
  604. The motto of the Jüelich Research Center in Jülich, Germany is "The Future is Our Mission" and supporting that future is this 2.5 meter high model of left handed DNA in the central library ... binoculars First reported on 2004 Nov 30, new as of 2004 Nov 30 (Thanks to A. Cherstvy, a.cherstvy@fz-juelich.de, for pointing this one out!)
    left handed DNA image permission granted for image
  605. Calbiochem Biologics Newsletters issues 30.1 (page 3) and 30.2 (page 15), In this figure a DNA that twists to the right and then switches to the left. Hmm. One of those must be the right way and the other is sinister! Even more confusing, how could the right one be the left one? That's right! This has left me confused. binoculars First reported on 2004 Dec 15, new as of 2004 Dec 15
    left handed DNA image permission granted for image
  606. People who have left handed DNA can now uses the services of Family Tree DNA to figure out who is right in family arguments and who should be left in the will. binoculars First reported on 2004 Dec 23, new as of 2005 Jan 6 (Thanks to Dan Graur, dgraur@uh.edu, for pointing this one out!)
    permission exclusive for image
  607. The Biozon.org database integrates left handed DNA, proteins and pathways. binoculars First reported on 2004 Dec 31, new as of 2005 Jan 6 (Thanks to b0b kuhn, for pointing this one out!)
    2005

    version = 1.48 of leftyear2005.txt 2009 Sep 29

    Our Story So Far: The story line, if you have not had time to follow the previous 608 or so entries (!) is my slow realization that earth is being invaded by left handed DNA people ...

    left handed DNA image permission requested for image
  608. The cover of the January 1, 2005 issue of LC-GC Europe has a left handed DNA. binoculars First reported on 2005 Jan 5, new as of 2005 Jan 28 (Thanks to Anthony Lewis, calewis@plymouth.ac.uk for pointing this one out!)
    left handed DNA image left handed DNA image permission requested for image
  609. Newsweek (January 17, 2005, Diet and Genes page 40) shows how eating left handed DNA is bad for you. Another cover link at newscom.com. binoculars First reported on 2005 Jan 12, new as of 2005 Jan 28 (Thanks to Adam Keen, lucidspectre@gmail.com, for pointing this one out and for the scan! Tamzon has returned and gave me some useful links too. Thanks also to Simon J. Rhodes, srhodes@iupui.edu for the cover link at newscom.com. )