The
Left Handed DNA
|
- Tom Schneider
|
version = 1.06 of leftyear2006.txt 2011 Aug 16
Our Story So Far:
The story line, if you have not had time to
follow
the
previous 635 or so entries
(!) is my slow realization that earth
is being invaded by left handed DNA people ...
NOTE: I am currently NOT adding entries often - too much else to do!! |
I would like to contribute one of my own papers to your left-handed DNA Hall of Fame. In the February 2 issue of Nature (Lee et al., Nature (2006) 439, 621-4), we describe single-molecule experiments that not only reveal some of the salient mechanistic details of DNA replication, but that also show that replication actually still works on left-handed DNA, a tricky experiment indeed. Figure 1 of the paper shows how the T7 bacteriophage replisome is assembled on a fork in a left-handed duplex (thanks to the casual and thoughtless mirroring of images...).The paper can be downloaded from nature2006.pdf First reported on 2006 Mar 7, as of 2007 Feb 11 (Thanks to Antoine van Oijen, antoine_van_oijen@hms.harvard.edu, for pointing this one out!)
Best,
Antoine
I saw this sculpture which graces the campus of the Marine Biological Laboratory in Woods Hole a few years ago and noticed that it was left-handed. Pam Clapp of MBL nicely went out and got a photo of it for me.Pamela Hinkle responded:
Attached please find a few photos of Helical Man by David Bakalar.There are three large images available: Helical Man 1, Helical Man 2, and Helical Man 3 First reported on 2006 Apr 6, as of 2006 Apr 6 (Thanks to Antonio Regalado, Antonio.Regalado@wsj.com, and Pamela Clapp Hinkle, pclapp@mbl.edu, for pointing this one out!)
For your first visit to the Left Handed Hall of Fame page I suggest that you follow the story over all of the years. After that you can look at each year individually from the table below. Note: just because a year has gone by does not mean we haven't found more examples for that year!
Year | Number of Left Handed DNAs |
---|---|
1964 | 1 |
... | - |
~1980 | 2 |
1978 | 1 |
1982 | 1 |
1983 | 2 |
... | - |
1989 | 3 |
1990 | 16 (5 from the Tessman letter) |
1991 | 6 |
1992 | 5 |
1993 | 6 |
1994 | 4 |
1995 | 9 |
1996 | 31 |
1997 | 37 |
1998 | 37 |
1999 | 77 |
2000 | 97 |
2001 | 105 |
2002 | 57 |
2003 | 55 |
2004 | 55 |
2005 | 44 (minimizing images) |
2006 | 17 (minimizing images) |
2007 | 26 (no images, sorry) |
2008 | 16 (no images, sorry) |
2009 | 23 (no images, sorry) |
2010 | 26 (no images, sorry) |
2011 | 11 (only 2 images, sorry) |
2012 | 11 (only rare images, sorry) |
2013 | 12 (only rare images, sorry) |
2014 | 12 (only rare images, sorry) |
2015 | 3 (images under Fair Use copyright policy) |
2016 | 2 (images under Fair Use copyright policy) |
2017 | 5 (images under Fair Use copyright policy) |
2018 | 7 (images under Fair Use copyright policy) |
2019 | 15 (images under Fair Use copyright policy) |
2020 | 13 (images under Fair Use copyright policy) |
2021 | 7 (images under Fair Use copyright policy) |
2022 | 10 (images under Fair Use copyright policy) |
2023 | 1 (images under Fair Use copyright policy) |
All | 868 |
updated: 2024Aug15_21:49:45